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Biomedical subjects

J Leonardelli

Publications and source records attributed to J Leonardelli.

At least 37 records · Page 2Linked to original sources
PubMed1977

Multiple clear-cell acanthoma (Degos): histochemical and ultrastructural study of two cases.

Two patients with clear-cell acanthoma with multiple lesions are reported; histologic and histochemical findings are similar to previous descriptions. The ultrastructural study confirms the overload of glycogen in keratinocytes, associated with an increase of mitochondria and nuclear deformations. The abundance of Langerhans' cells is emphasized. Extrusion of glycogen by keratinocytes and its phagocytosis by Langerhans' cells is suggested.

Aged↗
PubMed1976

[Effects of atropine sulfate on the hypothalamic LH-RH cells of the guinea-pig].

A single 30 mg/kg., s.c. injection of atropine sulfate into male guinea pigs produces a storage of LH-RH immunoreactive material in hypothalamic neurons. In diestrus female there is no increase of immunoreactive LH-RH substance in neuron and in eminential terminals; the rate of LH-RH synthesis may be still slight. The LH-RH immunoreactive neuronal increase, in male may be related to an atropine blockade of LH-RH portal cession, perhaps via infundibular dopaminergic neurons.

Animals↗
PubMed1975

[Hypothalamic mechanism of the antiovulatory action of sulpiride].

The antiovulatory effect of sulpiride is mediated via inhibition of the LH-RH release: when given during 10 days in guinea pigs, sulpiride is able to promote an increase of LH-RH immunoreactive substance in anterior hypothalamic and suprachiasmatic neurons. This storage probably related with inhibition of LH-RH release, is permitted by catecholamines, since metatyrosine administration prevent this sulpiride effect. On the other hand, when administered to hamsters sulpiride is able to promote stimulation of hypothalamic catecholaminergic neurons of tubero infundibular and anterior periventricularis nuclei. The hypothalamic aminergic action upon sulpiride antiovulatory effect is discussed.

Animals↗