Out of 77 thyrotoxic patients treated with Carbimazole (30-15 mg/day) in combination with 1-triiodothyronine (75 micron/day) for 5-48 months applying 20-min 131I-thyroid uptake test at the end of treatment as a parameter for thyroid suppressibility, 39 cases (51%) have maintained euthyroid state for more than 4 years, while 20 (26%) relapsed within 3 months and the remaining 18 (23%) recurred within 6 years after antithyroid-drug (ATD) therapy. The predictable value of 20-min 131I-thyroid uptake was useful for distinguishing relapses from others, but there was no statiscally significant difference between recurrent cases and remittent ones. Since the negative correlation between the 20-min 131I-thyroid uptake and the recurrent phase was noted, the continuation of ATD therapy until the uptake reaches below 8% postpones this phase of recurrence.

Adult↗

PubMedDate not supplied

[Prognostic evolution of Graves' disease treated by synthetic antithyroid (author's transl)].

A follow-up of at least 4 years after withdrawal of a medical treatment of 77 patients with Graves' disease is presented. The treatment consisted in Carbimazole (15-30 mg/d), LT3 (75 ug/d), Propranolol (30-60 mg/d), Hydroxyzine (75 mg/d). A normal thyroid suppressibility (20 mm 99m Tc uptake test) is obtained in patients without goiter faster than in those with goiter. A normal early uptake at the sixth month therapy is a good index for cure. Despite this result the authors recommend a treatment of 12 to 18 months duration because of the probable immunodepressive effect of the antithyroid drugs.

Antithyroid Agents↗

PubMedDate not supplied

[A case of intestinal invagination in Burkitt's lymphoma. Echographic and x-ray computed tomographic aspects].

The case of a young girl with cervical and abdominal lymphoma associated with small bowel intussusception is reported. The ultrasonographic and computed tomographic patterns of the intussusception and their physiopathologic agreements are reminded. Semeiologic elements which have not been already described are reported. This case also points out the difficulty in the diagnosis of intussusception when abdominal tumors are present.

Adolescent↗

PubMedDate not supplied

[Metastatic calcifications in Burkitt's lymphoma].

During the evaluation of a Burkitt lymphoma, a diffuse uptake of 99mTC MDP in the lungs and gastric mucosa, discovered by bone scintigram, allows the detection of metastatic calcifications. Bone scintigram appears to be an useful tool for the diagnosis and follow-up of these calcifications. The echographic pattern of the gastric involvement with both thick wall and mucosal calcifications, is reported.

Burkitt Lymphoma↗

PubMedDate not supplied

[Regressive pseudotumoural encephalopathy and hyperthyroidism. One case (author's transl)].

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Female↗