Biomedical subjects

J Larralde

Publications and source records attributed to J Larralde.

At least 91 records · Page 5Linked to original sources

PubMed1980

Electrochemical potential of calcium as index of intestinal permeability in rat and chicken.

The electrochemical potential of calcium between the serosal and the mucosal sides of the small intestine in both rat and chicken have been studied in vitro. Techniques to measure the Transmural Potential Difference and the Short-circuit Current Intensity have been used. Our results indicate that the permeability coefficient of calcium in rat intestine towards the serosal is sixfold over that towards the mucosal. In chicken intestine it is approximately of the same order on either side. The permeability coefficient is defined as the ratio delta Eexp/ delta Etheor, where delta Eexp stands for the difference, experimentally measured, of the electrochemical potential under two distinct conditions of calcium in the medium, and delta Etheor stands for its expected value under conditions of zero permeability.

Animals↗

PubMed1979

Effect of raw field bean (Vicia faba) on amino-acid-degrading enzymes in rats and chicks.

The effects of Vicia faba diet on urinary nitrogenous compounds and on enzyme activities of pathways directly associated with amino acid metabolism were studied in rats and chicks. The urea and creatinine excretion of rats fed on V. faba was approximately 90% more than that of control rats. The V.-faba-fed rats had increased activities of liver arginase (EC 3.5.3.1), argininosuccinate synthetase (EC 6.3.4.5) and alanine aminotransferase (EC 2.6.1.2). The chicks fed on V. faba also showed increased activity of xanthine dehydrogenase (EC 1.2.3.2). The possible nature of these altered amino-acid-degrading enzyme activities is discussed.

Alanine Transaminase↗

PubMed1977

Response of chicken intestine to calcium omission on electrical potential and short-circuit.

A comparison of the endogenous PD and ISC, galactose transfer PD and ISC, and leucine transfer PD and ISC by rat and chicken intestine in a buffer with and without calcium, was made. The electrical activity in presence or absence of actively transported substrates was altered in the chicken intestine when a calcium-free buffer was used. No significant differences were observed with rat intestine.

Animals↗

PubMed1975

Interaction between sugars and amino acids in intestinal absorption by rat, in vivo.

The inhibitory action of L-leucine on the intestinal absorption of D-glucose and D-galactose, as well as the inhibitory action of D-galactose on the absorption of L-leucine at various concentrations by rat small intestine has been studied. The further effect was more clearly evidenced when the medium was perfunded through the intestine in a closed circuit system using a peristaltic pump.

Animals↗

PubMed1975

Effect of coumarin and some coumarin derivatives on active transport and passive diffusion of sugars by chicken and rat intestine, in vitro.

The effect of coumarin, 4-hydroxycoumarin, coumarin-3-carboxylic acid and acenocoumarol on the active transport of D-galactose and the passive diffusion of arabinose by intestinal sacs was studied. All these substances, when added to the mucosal medium of incubation at concentrations from 10(-4) to 10(-3) M, inhibit the active transport of D-galactose and increase the diffusion of arabinose. Oxygen uptake by the intestinal tissue is only inhibited by coumarin-3-carboxylic acid. The results suggest that the effects obtained are probably due to an alteration in intestinal permeability, to inhibition of cell metabolism and to molecular size.

Acenocoumarol↗

PubMed1975

Specific response of chicken intestine to calcium influence on D-galactose absorption.

A comparison was made of the D-galactose uptake by rat, hamster and chicken intestine utilizing calcium-containing or calcium-free incubation fluid. The Wilson-Wiseman technique was employed. Qualitative differences were found in the response of the different intestines to calcium requirements as regards sugar active transport. No significant differences were observed in oxygen consumption.

Animals↗

PubMed1975

[Effect of various coumarins on the intestinal absorption of galactose in vivo (author's transl)].

The effect of various coumarins on the active transport of galactose by small intestine in chick and rat was studied, using the in vivo technique of sucessive absorptions. A 10(-4) M concentration of the different coumarins inhibits the absorption of galactose in the chick. This effect persists in successive absorptions without coumarin. In rat, inhibition of galactose active transport by coumarins was observed at 10(-3) M concentration.

Animals↗

PubMed1974