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Biomedical subjects

J Koller

Publications and source records attributed to J Koller.

At least 91 records · Page 5Linked to original sources

[The contribution of x-ray computed tomography in acute pancreatitis].

In acute pancreatitis. CT realize the best morphological examination not only for pancreas but also for extrapancreatic spread. However, ultrasonography is necessary for biliary lithiasis detection. Prognostic value of CT findings remains controversial and further studies are needed to clarify this problem. CT also permits to survey evolution and to detect eventual complications. Interventional CT, consisting in single-step needle aspiration or catheter drainage, allows in selected cases to avoid an unnecessary surgery.

Acute Disease↗

[Viability of pancreatic transplants].

28 consecutive organ donors were divided in 5 groups according to age (6 to 40, 40 to 65) shock and history of medication requiring hypertension. Electronmicroscopy, histology and immunohistochemistry of the exocrine and endocrine pancreatic tissue, of the ductal and vascular system revealed no abnormalities accept for donors with known hypertension. On the basis of these findings in the future we will remove pancreas from donors up to the age of 65 and from those having been in shock in order to meet the increasing demand for pancreas transplants.

Adolescent↗

Monitoring immunocompetent cells in the peripheral blood of stomach cancer patients after splenectomy and gastrectomy.

The status of lymphocyte subpopulations in splenectomized (Sx) stomach cancer patients (SCa-patients), assessed by monoclonal antibodies, has not been evaluated so far. Therefore subsets of peripheral white blood cells were monitored prior to and following surgical treatment in gastrectomized (Gx) and Sx (n = 64) as well as in non-Sx patients (n = 39). Postoperative surgical complications were more frequent in the Sx group. However, the 2-year survival rate of this group was higher than in non-Sx patients. Lymphocytes were significantly decreased in both groups of patients during the early postoperative period. Monocytes and polymorphonuclear cells (PMN) increased correspondingly. A significant loss of lymphocytes and their subsets in Sx patients was observed during the 1st-3rd postoperative days as compared to the Gx only patients. The OKT4/OKT8 ratios did not differ in either group of patients, whereas the OKT3+anti-B-Ly2 ratio was significantly increased in Sx patients 1 to 3 days postoperatively.

Antibodies, Monoclonal↗