[Secondary fibromyalgia. Differentiation of primary and secondary fibromyalgia is necessary for successful therapy].
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Diagnosis, Differential↗
Biomedical subjects
J Kelemen
Publications and source records attributed to J Kelemen.
Spinal factors in the generation of fibromyalgia syndrome.
In fibromyalgia as well as in low back pain we frequently find disturbances of the posture of vertebral column clinically and radiologically. Also, reduction in the mobility of whole spine and localized movement impairments in both conditions was present. It is likely that the disturbances are responsible for the first manifestations of fibromyalgia in a single localization, especially in lumbar and cervical regions.
Fibromyalgia↗
Orthostatic sympathetic derangement of baroreflex in patients with fibromyalgia.
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Adult↗
[Reliability and validity studies with the triflexometer, a new method for assessing form and flexibility of the spine].
Developed by Orthotronic Medizintechnik GmbH, the so-called Triflexometer, version 3.22 was tested for its reliability and validity in measuring spinal posture and mobility. Reliability studies on 20 healthy subjects have shown this measurement method to be reliable, yet intra- and inter-rater reliability analyses also revealed that even for this healthy population discrepancies in the various measures may occur, both due to differences in compliance as well as fatigue and learning effects, and due to difficulties in stabilization of the normal posture, to a lesser extent due to certain specifics of the measurement technique (placing the markers, guiding the sensor). In total spinal immobility (ankylosing spondylitis), practically identical measurements are found, as is the case in dummy studies. The validity study on 20 healthy subjects found good correlations between the measurements obtaining using the triflexometer and those for double inclinometer, respectively, and that only minor mean value differences occur for the two methods. Also, triflexometer measurements for total anteflexion were found to correlate with those determined with the fingertip-to-floor method, no correlation was present however between the Triflexometer values and the Schober test. Triflexometer measurements performed on 114 healthy subjects of various ages served to prove that the range of spinal movement in the directions measured (sagittal and frontal) will reduce with age. To a lesser extent, this also applies to hip movement. Overall, our findings prove the triflexometer an easy-to-handle system which possesses high reliability and is suitable for valid and objective noninvasive assessment of global and segmental spinal mobility. Triflexometer examinations are highly uncomplicated to implement, and print-outs of the results obtained permit lasting documentation of the present status.
Adult↗
[The diagnostic value of IgG galactosylation in rheumatoid arthritis].
Glycosylation is the main posttranslational modification of protein molecules. Human immunoglobulin G (IgG) is unique among serum glycoproteins because it is associated with at least 30 different biantennary oligosaccharide moieties. Elevated ratio of circulating IgG molecules lacking galactose from the oligosaccharides on the CH2 domain correlates with severity of the disease in a number of different autoimmune illnesses. Moreover, it may be helpful in differential diagnosis of rheumatoid arthritis (RA). By that we may try to predict outcome of RA. Its seems that agalactosyl IgG is distinctively connected with rheumatoid arthritis and may be involved in its immunopathogenesis.
Arthritis, Rheumatoid↗
[Systemic mastocytosis].
The systemic mastocytosis is a rare disorder, however, the authors recently diagnosed two cases causing diagnostic problems. The diagnosis was proved by bone marrow biopsy in both patients. The authors review the diagnostic pathway considering the pitfalls. According to their conclusion, the most important factor in the diagnosis of systemic mastocytosis is to think of the possibility of systemic mastocytosis.
Aged↗
Eco-grammar systems: a grammatical framework for studying lifelike interactions.
A formal framework for studying systems made up of a community of agents and their environment is proposed. The suggested model, technically based on the theory of formal grammars and called an eco-grammar system, captures some common features of ecological, economic, social, and collective robotic systems. The article contains an informal presentation as well as the formal definition of the model, presents some properties of variants of eco-grammar systems, and discusses the emergence of important lifelike features such as birth and death. Emphasis is put on results with relevance for artificial life. Some recent developments are also briefly reported.
Artificial Intelligence↗
Cytokine concentration in serum of lupus erythematosus patients: the effect on acute phase response.
In order to get a better insight into cytokine network regulation in systemic lupus erythematosus (SLE), we analyzed levels of interleukin-10 (IL-10), interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), and interferon-gamma (IFN-gamma) in the sera from 36 SLE patients. Moreover, C-reactive protein (CRP), alpha-1-acid-glycoprotein (AGP), and alpha-1-antichymotripsin (ACT) serum levels were evaluated. Serum levels of IL-10 and IL-6 were significantly increased when compared with healthy controls. TNF-alpha and IFN-gamma did not differ from normal values. We established the relationship between IL-10 and IL-6 as well as between IL-10 and TNF-alpha. None of the analyzed cytokines correlated with the acute phase protein levels. Based on the obtained data, we conclude that IL-10 may play the superior regulating role in SLE. A lack of correlation between the cytokines and acute phase proteins suggests their independence from cytokine regulation.
Acute-Phase Reaction↗
[The place of micro- and modern mini-laparotomy in the management of biliary calculi].
The authors treated 537 patients biliary stone disease between 1-st january 1991. and 1-st june 1994. With the conventional method of 20 cm of the subcostal incision, they operated 250 patients, among them 17 (6.8%) also had the common bile duct stone. There was no case of mortality and common bile duct injury. The postoperative morbidity was 12.8%. The average days of treatment was 9. With micro- and modern mini-laparotomy 287 cases were operated, 16 (5.5%) of them had common bile duct stones which were extracted during the process of cholecystectomy. In one case transduodenal sphincterectomy was performed. There was no case of mortality and injury of common bile duct. The postoperative morbidity was 10.4%. There was 6 cases of conversion (2.09%). The average period of treatment was 5 days. The treatment of biliary stone disease by micro- or modern minilaparotomy does not cause more danger to the patients than the conventional subcostal method. This approach is suitable for the surgical treatment of all kinds of biliary stone disease. This method is also suitable to extract a stone (stones) from the common bile duct discovered during cholecystectomy. This method has a pleasant cosmetical results.
Adolescent↗
Association of relative nocturnal hypertension and autonomic neuropathy in insulin-dependent diabetic children.
Twenty-four hour BP and heart rate measurements were carried out in fourteen newly diagnosed-, and in twenty-eight diabetics with 5-13 years of duration; and in eight healthy control children. Mean arterial BP rose at night in five-, fell slightly (less than 10%) in five- and fall markedly (more than 10%) in eighteen diabetics with longer duration of the disease. The diurnal-nocturnal difference of mean arterial pressure was significantly lower in the groups with nocturnal BP rise and slight nocturnal BP fall, compared to the control group (< 0.001; p < 0.01, respectively). The diurnal-nocturnal differences of heart rates were significantly lower in diabetics with relative "nocturnal hypertension" compared to the control group (p < 0.05). The presence of subclinical signs of diabetic autonomic neuropathy was significantly higher in patients with nocturnal BP rise and slight nocturnal BP fall compared to patients with marked nocturnal BP fall and newly diagnosed diabetics (chi squared p = 0.02 and p = 0.01, respectively). In conclusion, the prevalence of autonomic symptoms in diabetic children could be related to change in diurnal/nocturnal arterial BP, however longitudinal studies of ABPM are needed to define, whether patients with abnormal BP profiles are candidates for the development of diabetic vascular disease.
Adolescent↗
[Selenium supplementation with bread].
Bread produced with selenium-enriched yeast was given to ten volunteers. The daily dose contained approximately 100 micrograms of selenium. The subjects' mean baseline whole blood selenium concentration (52.2 +/- 16.7 micrograms/l) was indicative of a suboptimal selenium status. After two weeks of supplementation, the subjects' mean whole blood selenium level increased significantly (to 66.1 +/- 11.9 micrograms/l). Supplementation of selenium-enriched bread seems to be an easily implementable and promptly acting method of selenium status improvement.
Adult↗
Relative nocturnal hypertension in children with insulin-dependent diabetes mellitus.
Twenty-four-hour blood pressure and heart rate measurements were carried out in 14 newly diagnosed diabetics and in 28 diabetics with 5-13 years' duration of the disease; 8 healthy children were used as controls. Mean arterial blood pressure increased at night in 5, decreased slightly (less than 10%) in 5 and decreased markedly (more than 10%) in 18 diabetics with longer duration of the disease. The diurnal-nocturnal differences in heart rates were significantly lower in diabetics with relative "nocturnal hypertension" compared to the control group (p < 0.05). A significant negative correlation was found between maximal arterial blood pressure during physical exercise and the diurnal-nocturnal differences in mean arterial blood pressure in diabetics (r = -0.58; p < 0.02). In conclusion, we found elevated nocturnal blood pressure in a subgroup of children with longer duration of diabetes and without increased albumin excretion. However, longitudinal studies of blood pressure profiles are needed to identify the candidates for diabetic vasculopathy among diabetic children.
Adolescent↗
Selenium in the blood of patients with colorectal cancer and neoplastic polyp.
Samples of whole blood were obtained from 51 patients with newly diagnosed colorectal cancer as well as from 76 patients with neoplastic colorectal polyp, and from 30 healthy blood bank donors. Selenium was determined by the fluorimetric method. Significantly decreased selenium concentrations of blood samples from patients with colorectal cancer and villous adenoma were found. There was not any correlation between the blood selenium levels of patients with adenomatous polyp and the severity of dysplasia in removed polyps. The lowest mean selenium level in patients with villous adenoma indicates that selenium deficiency may be an important factor in the development of colorectal cancer arising from villous adenomas.
Adenoma↗
Prognostic data of the second follow-up in childhood wheezy bronchitis.
206 non-selected children who had wheezy bronchitis before two years of age were observed in the first follow-up (1985) about 9 years after their clinical wheezy episode. Among them 31 patients (15%) showed bronchial hyperreactivity (B.H.) after acetylcholine challenge and 9 children became asthmatic. In the second follow-up (1988) 28 children who had B.H. and randomly 17 children who did not have B.H. participated. The prognosis of wheezy bronchitis is good, there was no new asthmatic child at this time. The B.H. was found to diminish only in 7 cases. During the last 3 years wheezy episodes developed only in 5 asthmatic patients. The skin prick test (SPT) positivity did not change (26% versus 29%). The familial atopy in the group B.H. is higher (43%) than in the group non B.H. (23%) but the difference is not significant (X2 = 1.72). No significant correlation was found between the familial atopy and SPT positivity. The familial smoking is higher in the group B.H. (78% versus 64%) but no significant influence on the B.H. (X2 = 1.03) could be detected.
Bronchitis↗
Effect of parental smoking on wheezy bronchitis and bronchial hyperreactivity.
In the course of the follow-up of 206 previously obstructive bronchitis children, the effect of parental smoking upon the occurrence of respiratory diseases, the yearly frequency of wheezing episodes and the age until the obstructive episodes used to return have been investigated. Familial and maternal smoking was more frequent in this group compared to the control group. In spite of this, however, no correlation could be detected between familial smoking and frequency of respiratory diseases, as well as the above mentioned characteristics of obstructive bronchitis. The familial smoking did not seem to influence the bronchial hyperreactivity challenged with acetylcholine, although the prevalence was higher.
Adolescent↗
[Xerostomia as a side effect of drugs].
After a definition of xerostomia and a description of it's diagnostics and consequences the most important etiological factors are reviewed with special emphasis on drugs inducing xerostomia as an adverse effect. The most important drugs concerned are summarized in a table indicating generic names as well as proprietary names of preparations marketed in Hungary. Possible therapeutic approaches are also described.
Age Factors↗
The dynamics of personality. An East European view.
As the debates on fundamental issues of the human sciences have shown, actually two significant pictures of man are opposed to each other: the scientific-biological and the historicist conceptions. The second one is supported, for instance, by the Budapest School of Philosophy (with Lukács and his followers) and the Soviet School of Psychology (Vigotsky, Luria, Leontiev and their pupils). Summing up the doctrines of these two currents of thought the author argues in favour of the historicist conception and indicates, what is implied, in different fields of application (mind-body problem, linguistic theories, neuropsychic diseases, mental disorders), by the acceptance of this point of view. Moral issues, concerning psychiatric treatment, are discussed, too, and a Kantian solution of them is defended.
Cross-Cultural Comparison↗
[Etiology, clinical picture and forensic assessment of the battered child syndrome. II].
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Battered Child Syndrome↗