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Biomedical subjects

J K Stanghelle

Publications and source records attributed to J K Stanghelle.

72 records · Page 4Linked to original sources
PubMed1986

Pulmonary function and oxygen uptake during exercise in 11-year-old patients with cystic fibrosis.

Ten patients with cystic fibrosis (CF), 5 girls and 5 boys, 11 years of age, underwent pulmonary function and bicycle exercise testing. The material includes all but 2 CF patients in this age group in southern and eastern Norway. The CF children had a moderately reduced pulmonary function, the girls more pronounced than the boys. The mean maximal oxygen uptake (max VO2) in the CF boys was 55 ml/kg/min (94% of age predicted value; range 79-105%), and the CF girls 42 ml/kg/min (79% of age predicted value; range 67-89%). The mean maximal peak heart rate was 195 beats/min. Only one CF girl showed apparent pulmonary limitation during exercise. Increased ventilatory equivalent for oxygen was found during both rest and exercise for the CF girls, but only during rest for the CF boys. Max VO2 was fairly well related to the habitudinal physical activity of the children (r = 0.79).

Child↗
PubMed1984

Pulmonary function and oxygen uptake during exercise in 16 year old boys with cystic fibrosis.

Eight of altogether 9 Norwegian boys with cystic fibrosis (CF), aged 15-17 years, and 8 healthy boys of the same age underwent pulmonary function and bicycle exercise testing. Although the CF boys showed large individual variations, the two groups showed great differences in mean body height and weight, pulmonary function variables and maximum oxygen uptake. The maximum oxygen uptake for the CF boys ranged from 40 to 125% (mean 79%) of predicted values. Increased ventilatory equivalent for oxygen was a characteristic finding during rest and exercise for the CF boys, and their oxygen uptake was higher during rest and corresponding work loads compared with the controls. As physical training is beneficial in cystic fibrosis, such exercise tests are of value for prescribing individual training programs and in evaluating their effects.

Adolescent↗
PubMed1983

The successful completion of the Oslo Marathon by a patient with cystic fibrosis.

Metabolic consequences of prolonged, severe exercise were investigated in a well trained 16-year-old boy with cystic fibrosis (CF) who completed the Oslo Marathon (42 195 m). His CF was diagnosed 6 years earlier. He had minimal radiological lung changes and a maximal oxygen uptake of 63.0 ml/kg/min. Several blood, urine and lung function parameters as well as body weight, fluid intake and rectal temperature were measured. None of the findings differed from those reported in healthy marathoners. Interestingly, no changes were found in the serum concentrations of electrolytes.

Adolescent↗
PubMed1983

Angina pectoris and cold.

Ten patients with angina pectoris and a history of cold intolerance performed symptom limited work tests at +18 degrees C and at -17 degrees C. At -17 degrees C the work capacity was found to be 20% lower than at +18 degrees C. In nine of the patients the work load necessary to elicit anginal pain was lower in the cold. Nitroglycerine given before cycling increased the work capacity in the cold to levels obtained in room temperature, mainly due to a decrease in the systolic blood pressure.

Adult↗
PubMed1983

Cardiovascular responses to static-dynamic work in young men, middle-aged athletes, and coronary patients.

The cardiovascular responses to combined static-dynamic work were measured in three groups of subjects: young men, middle-aged athletes, and coronary patients. The highest work capacity was found in the middle-aged athletes and the lowest in the coronary patients. In all instances the highest values of the rate pressure products were found in the coronary patients and the lowest in the middle-aged athletes. This study indicates that systolic blood pressure response to static-dynamic work increases with age and that lifelong endurance training and being a non-smoker does not seem to alter this.

Adult↗
PubMed1983

Cross-country skiing in coronary patients.

Since 1979, 33 coronary patients have participated altogether 52 times in the Ridderrenn, a 22 km cross-country ski race for handicapped persons. No complications occurred during the races. The authors conclude that cross-country skiing as a recreational activity can be enjoyed by many coronary patients, provided that extremes of cold and high-intensity exercise are avoided.

Adult↗
PubMedDate not supplied

Cognitive performance in multiple trauma patients 3 years after injury.

OBJECTIVES: Patients with sequelae from multiple trauma commonly display cognitive disturbances, specifically in the areas of attention and memory. This study was designed to assess cognitive functioning 3 years after severe multiple trauma and to investigate how cognitive performance is related to head injury severity and psychological distress respectively. METHODS: Sixty-eight multiple trauma patients were tested with a screening battery consisting of six neuropsychological tasks 3 years after injury. A measure of psychological distress (20-item General Health Questionnaire, or GHQ-20) was also administered. RESULTS: Patients who neither showed signs of reduced consciousness on admission to the hospital nor reported significant psychological distress at follow-up tended to have normal test performance. In five of the six tasks, cognitive impairment was related to the severity of the traumatic brain injury as measured by the Glasgow Coma Scale (GCS). In both attention span tasks, patients designated as cases by the GHQ had significantly lower scores than noncase patients. These bivariate relationships were upheld in multiple regression analyses, in which age, sex, and GCS and GHQ scores were entered as independent variables. When patients with severe head injuries were excluded from the analyses, GCS scores still contributed to the variance in tests of verbal attention span and delayed recall, but performance on attentional tasks was more strongly related to psychological distress than to GCS scores. CONCLUSIONS: Cognitive deficits in multiple trauma patients were related both to the severity of the traumatic brain injury and to the degree of psychological distress. The strength of the association between brain injury as indicated by GCS scores and cognitive performance differed between different tasks. Neuropsychological testing may assist in differentiating primary organic from secondary psychogenic impairments.

Adolescent↗
PubMedDate not supplied

Eight-year follow-up of pulmonary function and oxygen uptake during exercise in 16-year-old males with cystic fibrosis.

Eight of nine Norwegian 16-year-old males with cystic fibrosis, and six age-matched, physically active controls were included in an eight-year follow-up study, involving pulmonary and bicycle exercise testing. The individual's level of regular physical exercise was registered, and we investigated whether or not this could be correlated to changes in clinical status, lung function and maximal oxygen uptake. Four males with cystic fibrosis trained regularly for 4-7 h weekly, while the other four patients did no regular exercise. Three of the latter died during the study, and the fourth male in the non-training group deteriorated significantly during the study period of eight years. The four males in the training group showed improvement in lung function parameters and maximal oxygen uptake, but two of them had more marked obstructive lung disease after the age of 24 years. Even though the sample was small, and several other factors may influence the results, the study indicates that regular physical exercise has beneficial long-term effects on clinical status, lung function and physical fitness in adolescent cystic fibrosis males.

Adolescent↗