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Biomedical subjects

J Jensen

Publications and source records attributed to J Jensen.

At least 577 records · Page 32Linked to original sources
PubMed1978

CT whole-body scanning in pediatric radiology.

In an 8 month period 57 scans in 28 children have been performed using an EMI-CT 5005 General Purpose Scanner. Thirteen primary malignant tumours were evaluated, and scanning was of great value in localizing and delineating the lesion, and hence predicting the operability. Furthermore, secondary spread of malignant tumours was easily detected. In the continuing evaluation of treated malignant tumours CT has been used to estimate regression and relapse.

Abdominal Neoplasms↗
PubMed1978

The effect of prednisone on serum thyrotropin, thyroxine and triiodothyronine concentrations in hypothyroid patients.

The effect of exogenous prednisone on serum thyrotropin (TSH), thyroxine (T4), and triiodothyronine (T3) concentrations was investigated in four patients with non-functioning thyroid glands receiving T4 replacement therapy. Orally administered prednisone, in a dose of 20 mg each day for nine days, resulted in a significant decrease in mean serum TSH levels (p less than 0.01) without significant changes in levels of serum T4, T3, and thyroxine binding globulin (TBG). These findings suggest an inhibitory action of relatively low pharmacologic doses of prednisone on TSH release without changes in circulating thyroid hormone concentrations or inhibition of the peripheral conversion of T4 to T3.

Adult↗
PubMed1978

Lymph node identification in carcinoma of the colon and rectum. Value of tissue specimen radiography.

A method for identifying lymph nodes in tissue specimens from patients with carcinoma of the colon and rectum by soft X-rays is described and assessed. The method seems superior to more time-consuming and possibly tissue-damaging procedures, and it affords a possibility of identifying lymph nodes down to a size 1--2 mm in formalin-fixed as well as in non-fixed tissue specimens.

Carcinoma↗
PubMed1977

Inner ear malformations with oto-liquorrhea. Tomographic findings in three cases with a mixed hearing impairment.

The paper deals with three boys suffering from a mixed hearing loss. They were all referred to tomography of the temporal bones in order to find some middle ear malformation amenable to surgery. The tomograms revealed identical malformations of the inner ear; the lumen of the labyrinth are found irregularly dilated and the internal acoustic meatus is widened. Its course in the lateral end is abnormal with a downwards turn towards the basal coil of the cochlea. Explorative tympanotomy in one of the patients revealed a severe otoliquorrhea during an attempt to perform a stapedectomy, and this may serve as a warning against operation in patients presenting the mentioned tomographic changes which, once seen, are easily recognized.

Adolescent↗
PubMed1977

Complement studies in adipose patients treated with intestinal bypass.

Seventeen consecutive patients subjected to jejunoileostomy for obesity have been investigated for complement abnormalities and cryoglobulinaemia. The study took place 1-9 1/2 years after the operation. A concomitant clinical examination revealed recurrent arthritis in 6 (30%) of the patients. In 6 of the patients complement abnormalities were found, as activation of the classical pathway in 3 and activation of the alternative pathway in another 3 could be suspected from immunochemical data. One patient showed activation of both the classical and the alternative pathway. Two of the patients with arthritic symptoms belonged to the group showing activation of the alternative pathway. It is suggested that deficient inactivation of bacterial products from intestinal bacteria (lipopolysaccharides) have a role in the complement abnormalities found. No patient exhibited the cryoprotein complexes found earlier in this type of patients.

Arthritis↗
PubMed1977

Low dose heparin in major surgery: clinical relevance of plasma heparin concentrations.

56 patients undergoing elective major surgery received low dose heparin prophylaxis, 5,000 IU 2 h before surgery and every 8 h for 7 days. The patients were tested by the 125I-fibrinogen uptake test, which, if positive, was controlled by venography. The heparin concentrations were measured by the method of DENSON and BONNAR and by the chromogenic method of TEIEN et al. in blood samples drained immediately before and after surgery and on the 1st and 5th postoperative day 2 and 4h after the injection of heparin. The values were found higher when estimated by the method of DENSON and BONNAR than by the chromogenic method. Deep vein thrombosis (DVT) developed in 11 patients, and in 10 of them within the first 48 after the operative procedure, in 1 after 4 days. The preoperative values were not lower in the patients who developed DVT, and the heparin concentrations found on the 1st and 5th postoperative day were at the same level as in those who did not develop DVT.

Adult↗
PubMed1976

Adenosine diphosphate binding to sodium-plus-potassium ion-dependent adenosine triphosphatase. The role of lipid in the nucleotide-potassium ion interplay.

Delipidated dogfish rectal-gland Na++K+-ATPase (Na++K+-dependent adenosine triphosphatase), almost devoid of hydrolytic activity, is able to bind about 2nmol of ADP/mg of protein. The "affinity" of delipidated enzyme for ADP is not affected by K+ in concentrations that greatly decrease the "affinity" of native Na++K+-ATPase. The K+-sensitivity of the ADP binding is in part restored by relipidation with dioleoyl phosphatidylcholine.

Adenosine Diphosphate↗