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Biomedical subjects

J Jensen

Publications and source records attributed to J Jensen.

At least 397 records · Page 22Linked to original sources

An attempt to operationalize reactive delusional psychosis.

Reactive psychosis is a diagnostic concept widely used in Scandinavia but it is still a subject of discussion and controversy internationally. Inside Scandinavia the diagnosis is used according to varying criteria, which is one of the reasons for high diagnostic instability and a threat to the validity and reliability of the concept. This article presents an attempt to operationalize reactive delusional psychosis, to test its clinical utility in a pilot study, and to test the reliability of the individual items. More clinical studies based on operationalization, demarcation of the concept, and interrater reliability are needed to convince psychiatrists outside Scandinavia of the existence of reactive psychosis as a useful nosological concept in patients with good prognosis and who mainly need psychotherapy.

Adolescent↗

Socket loosening in arthroplasty for congenital dislocation of the hip.

Mechanical risk factors in loosening of the socket were radiographically analyzed in 123 Charnley arthroplasties performed during the period 1969-1982 for coxarthrosis secondary to congenital dislocation. The socket was placed as near the true acetabulum as possible without extensive soft-tissue release and without reinforcement of the acetabular roof by bone grafting. The rate of socket loosening was 19 percent using progression of a radiolucent line at the bone-cement interface to a width of greater than 1 mm as the criterion for loosening. Different predictors of loosening were analyzed by stepwise logistic regression analysis. Lack of lateral bony support for the socket was the prime predictor. The next most important predictors were the preoperative degree of hip dislocation and the position of the socket in relation to the true acetabulum.

Acetabulum↗

Forty-six patients with primary sclerosing cholangitis: radiological bile duct changes in relationship to clinical course and concomitant inflammatory bowel disease.

The clinical features of primary sclerosing cholangitis were studied in 46 consecutive patients. Jaundice was the most common symptom (57%), followed by pruritus (28%), pain (24%), and fever (15%). Thirty-three per cent of the patients had no symptoms, merely laboratory changes. No significant relationship was observed between a numerical score of radiological bile duct changes at diagnosis and the clinical picture, or the clinical course during follow-up. If clinical deterioration occurred, this seemed to happen within the first eight years after the clinical presentation. Patients with only intra-hepatic bile duct changes (n = 10) did not differ clinically from those with extrahepatic changes as well. Forty-three out of 44 patients examined had inflammatory bowel disease, usually ulcerative colitis, with total colitis in 84%. Radiological bile duct changes had a significantly higher score in patients who had to be treated with a combination of sulfasalazine and steroids, suggesting a weak relationship between severity of bowel disease and bile duct disease.

Adult↗

Charnley arthroplasty in osteoarthritis secondary to congenital dislocation or subluxation of the hip.

A follow-up study was made on 129 consecutive Charnley arthroplasties in osteoarthritis secondary to congenital dislocation of the hip. The acetabular component was placed as far distal as possible using a standard technique. Bone grafting was not performed. The survival of the prostheses was assessed by the survivorship method. The cumulative survival rate of the prostheses was 93% after five years, 89% after ten years, and 80% after 15 years. In 77% of the cases the acetabular component had been placed in the true acetabulum or levels the rate of mechanical loosening of the acetabular levels the rate of mechanical loosening of the acetabular component (revisions and acetabular components showing a radiolucent line of increasing width) was 13% compared with 42% in the group where the acetabular component was placed proximal to the roof of the true acetabulum (p less than 0.005).

Adult↗

Diagnostic reliability of combined physical examination, mammography, and fine-needle puncture ("triple-test") in breast tumors. A prospective study.

A prospective study of 622 consecutively registered patients with 650 breast tumors was performed to appraise the reliability of combined physical examination, mammography, and fine-needle puncture (triple test) in the preoperative diagnosis of such tumors. All malignant as well as benign test results were confirmed by subsequent histologic examination. The diagnostic accuracy of the triple test at benign changes is comparable to that of histologic examination, but participation of experienced radiologists and cytologists as well as persons skilled in fine-needle puncture is required. Twenty-eight percent of the planned excisional biopsies were made superfluous by the fine-needle puncture, which immediately revealed the tumor as a cyst, abscess, or hematoma. For this reason, too, fine-needle puncture is recommended as a routine procedure.

Biopsy, Needle↗