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Biomedical subjects

J J Merland

Publications and source records attributed to J J Merland.

At least 181 records · Page 10Linked to original sources

[Superficial cervicocerebral angiomas. Should complementary tests be required?].

A computer-assisted study of 772 patients with haemangiomas and vascular malformations was conducted during a 2-year period with special attention to complications and associated anomalies, such as laryngeal, meningeal or cerebral vascular malformations. We report here the data obtained from 397 of these patients totalling 401 superficial haemangiomas and vascular malformations of the head and neck. We classified the lesions into immature angiomas, growing and subsiding during childhood, and mature vascular malformations with a life-long development, themselves divided into arteriovenous, capillary and venous malformations. We found that each group had its own specific complications. Severe complications, notably vascular brain lesions, were eventually observed in patients with superficial arteriovenous malformations of the head. Extensive complementary investigations, including CT scans and arteriography, are therefore not justified in every case. Guidelines are offered to evaluate the risk according to the clinical diagnosis.

Brain Neoplasms↗

[Diagnostic and therapeutic angiography in the evaluation and treatment of glomus jugulare tumors. Apropos of 32 cases].

This report is based on 32 cases of jugular paraganglioma treated by embolization, of which 7 had cervical and/or intrajugular extensions, five a giant extension involving mainly the carotid canal and one excretory activity. Aims and methods of diagnostic and therapeutic angiography are envisaged as well as results in the three angiographic types encountered: tumors vascularized by the external carotid artery only, those supplied by the internal (and external) carotid arteries and those fed by the vertebral artery or even the three arterial axes.

Angiography↗

Facial port-wine stains and Sturge-Weber syndrome.

A retrospective study was made of 106 cases of facial port-wine stains. It was concluded that only patients with lesions located in the ophthalmic (or V1 trigeminal) cutaneous area are at risk for associated neuro-ocular symptoms. It is proposed that Sturge-Weber syndrome results from a dysmorphogenesis of cephalic neuroectoderm.

Adolescent↗

[Tumors and vascular malformations of the larynx. Angiographic aspects and therapeutic indications].

Satisfactory results were obtained in a case of laryngeal paraganglioma following surgery preceded by angiography and embolization. Clinical, arteriographic and histologic features of vascular malformations of the larynx are discussed, localized and isolated laryngeal angiomas being distinguished from those classified among cervicofacial angiodysplasias. Laryngeal vascular malformations are all capillarovenous angiomas. Treatment has been facilitated by the availability of arteriography and embolization methods, and consists of injections of a sclerosing agent (such as "ethybloc") together with surgery in some cases.

Adult↗

The treatment of capillary-venous malformations using a new fibrosing agent.

We present our early experience in the treatment of cutaneous capillary-venous malformations using a new fibrosing agent called Ethibloc. Superselective angiography was used to delineate the vascular anomaly and effect temporary occlusion. Whenever possible, compression of venous outflow also was used, while the sclerosing agent was injected directly into the malformation by percutaneous puncture. Sixteen patients with capillary-venous malformations have been treated with this agent since 1979. A mild local inflammatory reaction was noted in some cases; there were no instances of skin necrosis. In 10 patients, the fibrosed vascular malformation was excised, and in 6 patients, the area of vascular anomaly decompressed to such a degree that resection was unnecessary.

Adolescent↗