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Biomedical subjects

J Horiuchi

Publications and source records attributed to J Horiuchi.

At least 127 records · Page 7Linked to original sources
PubMed1984

[Prognosis of long-term survivors of oral cancer treated with radiation].

The prognosis after long-term survival was analyzed for 645 patients with oral squamous cell carcinoma treated primarily with radiotherapy. In contrast to the fact that the main cause of death within five years was related to the primary disease (92%), the estimated causes of death after five years were related to the primary disease in 22% and to other malignant tumors in 15%; this was particularly so in the middle age group (29%). As for the patients who showed local recurrence after long periods the possibility of radiation-induced cancer might be considered; however, it was difficult to distinguish radiation-induced cancer from late recurrence.

Adult↗
PubMed1983

Relation between extension of non-Hodgkin's lymphoma and lymphographic findings.

The relationship between the degree of lymph node foaminess observed in bipedal lymphadenograms and absolute peripheral lymphocyte counts in non-Hodgkin's lymphoma was analyzed with regard to the initial location, clinical stage, histologic subtype, and bulkiness of the disease. In the nodal type of disease with supra-diaphragmatic presentation, an inverse relation was often found between the peripheral lymphocyte count and the foaminess score. However, if the disease originated in the infra-diaphragmatic regions no such relation was found. The implications of these observations are discussed.

Humans↗
PubMed1983

[Metachronous triple malignant lymphoma of the stomach].

A 72-year-old female who had undergone partial gastrectomy (Billroth I method) 8 years earlier because of a diagnosis of malignant carcinoma of the stomach (histopathological diagnosis: ML. Histiocytic, Diffuse--Rappaport--) visited our hospital because of dysphagia for the past three months. X-ray and fiberscopic examination revealed the same malignancy in the remnant stomach. Curative extirpation of the remnant stomach, resection of the lower esophagus and pancreatosplenectomy were performed. There were two lesions in the resected specimen. One was a large tumor of Borrmann 3 type (8 cm in diameter) at the EGJ; the other was a small IIc-like tumor (2 cm in diameter) at the surgical stump on the lessercurvature. These three metachronous malignant lymphomas returned the same pathological findings. Compared to carcinoma, malignant lymphoma of the stomach occurs more frequently in the fornix and the tendency for multiple occurrence is strong. When partial gastrectomy is performed for malignant lymphoma of the stomach, follow-up of the remnant stomach must be carried out carefully.

Aged↗
PubMed1982

Reappraisal of trimodal combination therapy for maxillary sinus carcinoma.

The introduction of trimodal combination therapy (surgery + radiation + intraarterial infusion) for maxillary carcinoma resulted in a change in the sites of recurrence and no satisfactory improvement in the local control rate. To examine the cause of these phenomena, external carotid angiography was performed on 51 patients prior to the start of the therapy and the results of the treatment were studied. Angiographic findings indicated that maxillary carcinoma is fed not only by the maxillary artery, but also by the internal carotid, facial, transverse facial and other arteries from the external carotid artery. The multiplicity of feeders causes irregular distribution of the intraarterially infused antimetabolites. Irregular and local low distribution of antimetabolites may well bring about the high rate of recurrence. The results of intraarterial transcatheter TC-99m-MAA injection were also in accord with the angiographic findings.

Adult↗
PubMed1982

Results of brachytherapy for cancer of the tongue with special emphasis on local prognosis.

One hundred and sixty-six patients with squamous cell carcinoma of the tongue were treated with radiation. Treatment modalities were mainly interstitial implant with or without external beam irradiation, except for early lesions, which were treated with intraoral electron beam therapy. Analysis was made on the local prognosis of the lesion to clarify the indications for interstitial therapy, especially the combined program with external beam therapy, and the time-dose relationship of the brachytherapy. Local recurrence-free rates (two years) were 94% in T1, 77% in T2 and 32% in T3 lesions, respectively. For T1 and superficial or exophytic T2 lesions, the local recurrence-free rate was excellent with the interstitial therapy alone using either permanent implants of gold grain or radium implants. Therefore, prior external beam therapy seemed to be unnecessary for these lesions. When the treated area was less than 10 cm2, subsequent complications were not likely even if the TDF (time-dose factor) value was high. Most of the patients who received combined external beam and interstitial therapy showed infiltrative T2 and a majority of the T3 lesions. In these patients, it was apparent that most of the total dose should be given from the interstitial implant after a small prior dose with external irradiation, because these lesions could not be cured even if the external dose was increased.

Adult↗
PubMed1982

Carcinomas of the esophagus with synchronous or metachronous primary carcinoma in other organs.

Twenty-eight patients with esophageal carcinoma and one or more separate primary carcinomas in other organs were treated from 1960 to 1980, representing 8.3 per cent of the 339 cases of esophageal carcinoma observed during this period. The most frequent sites of the additional tumors were the oral cavity and pharynx (11 patients) and the stomach (12 patients). Awareness of the frequent combination of esophageal carcinoma with other primary neoplasms in the sites mentioned may lead to the detection of small curable malignant tumors.

Aged↗
PubMed1982

Extranodal non-Hodgkin's lymphoma in the head and neck. Irradiation and clinical course.

A retrospective analysis was performed of localized extranodal non-Hodgkin's lymphomas in the head and neck region treated with irradiation. Histopathologic reevaluation revealed 94 per cent with a diffuse type. The lesions were as a rule locally cured with doses ranging from 30 to 50 Gy. Relapses in localized stage I and II patients were, however, not seldom observed in distant extranodal sites. Gastrointestinal relapse in cases with lesions originally located in Waldeyer's ring was thus frequently observed, and the probability of multiple or systemic involvement should be considered also when the disease is located in the oral cavity or sinus region. The value of systemic examination for staging purposes is discussed.

Adolescent↗