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Biomedical subjects

J Hoff

Publications and source records attributed to J Hoff.

At least 73 records · Page 4Linked to original sources

[Rupture of the left diaphragmatic cupola with pericardiac rupture complicated by heart luxation. Apropos of 2 new cases].

Pericardiac rupture associated with a rupture of the left diaphragmatic cupola is a seldom possibility. This possibility is principally observed during important thoracic and abdominal traumatism. Heart luxation through the pericardiac break is a complication which can involve brutal death, stay unknown or be an operative discovery. Two new cases of left diaphragmatic cupola rupture are related. The authors analyse ways of this pericardiac luxation, definite diagnostic components and the therapeutic methods. Prognosis stays serious because of the importance of the associated lesions.

Adult↗

[Shoulder movements after mammectomy with conservation of muscle. Report of 100 cases].

One hundred patients were treated by a Patey type conservative radical mammectomy with or without associated radiotherapy. Objective numerically rated comparison of the frequency and degree of limitation of the different shoulder movements after surgical treatment alone showed that abduction was the movement most markedly and frequently limited. This was followed, in decreasing order of frequency and degree, by limitation of amplitude, anterior flexion, external rotation, posterior flexion, and internal rotation. In cases with associated radiotherapy, highest percentages of maximal imitation for each movement occurred in those undergoing pre-operative cobalt therapy, and particularly involved abduction, posterior flexion, and external rotation. Patey type mammectomy provides improved functional results when compared with the classical Halsted's operation, but its technique has still to be perfected, a useful basis for this being a detailed analysis of its possible sequelae.

Adult↗

[Osteosis deformans of thyroid origin. Radiological, histomorphometric and pathophysiological study (author's transl)].

A 73-year-old woman with severe, old standing thyrotoxicosis developed osteosis with deformities of the lower limbs and spine resembling osteomalacia. All the well-known radiological, and histomorphometric features of thyroid osteosis were caricaturally present in this patient who, in addition, exhibited curvatures of the lower limbs that are exceptionally described in hyperthyroidism. A study of standard phosphorus/calcium values, 25 OH D values, circulating parathyroid hormone levels and fractional absorption of 47Ca before and after thyroidectomy enables the authors to discuss the current pathophysiological concepts concerning phosphorus/calcium and bone metabolism in hyperthyroid conditions. A possible action of thyroid hormones on vitamin D metabolism or peripheral effects is envisaged.

Aged↗

[Ultrastructural morphometric changes in spiral ganglion cells of the rat after broad band noise (author's transl)].

The comparison of ultrastructural and ultrastructural-morphometric findings in spiral ganglion cells subsequent to broad noise with 105 dB SPL over a period of 40 min demonstrates that there are morphometric changes of the cytoarchitecture of granular ganglion cells even without evident ultrastructural changes. Morphometric analyses shows a significant extension of the volume proportion of mitochondria per unit volume cytoplasm. The volume and the surface of the rough endoplasmic reticulum, the volume of the free ribosomes and the average single volume of the nucleoli increase per granular ganglion cell. The physiologic significance of these changes is discussed. The results show that changes of the cytoarchitecture of granular spiral ganglion cells are earlier detected by morphometry than by ultrastructural description.

Acoustic Stimulation↗

[Recurrent infectious parotiditis in the child (author's transl)].

On the basis of 18 cases of recurrent parotiditis in the child, the authors offer the current review of this condition: clinical features, radiological features, bacteriological features, course. They emphasize the importance of precise technique during sialography, which must include straight and lateral films. The progress of this condition is characterised by recurrences. These may be avoided by prolonged and appropriate antibiotic therapy. The improvement which takes place at puberty is of etiopathogenic significance. Bucco-dental septis, constantly present, is one of the causes favourising infectious parotiditis in child.

Bacterial Infections↗

Spontaneous spinal epidural haemorrhage: good results after early treatment.

Extravasation of blood in the spinal epidural space is an uncommon but often disastrous problem. Severe trauma, anticoagulants, bleeding diatheses, and intraspinal vascular malformations have been associated with such haemorrhage, but occasionally it occurs without apparent cause. It may then be confused with transverse myelopathy or vascular occlusion. Early diagnosis by myelography and treatment by surgery can result in good recovery, as illustrated by two cases.

Adolescent↗

Clinical, arteriographic, and cisternographic observations after removal of acute subdural hematoma.

The authors review 47 patients with closed-head injuries requiring treatment for acute subdural hematoma and report that 21 (45%) survived for 5 days or more. Follow-up study of these 21 survivors led to the following observations: that clinical evaluation of these patients is the most reliable index of their postoperative progress; that the diagnostic usefulness of postoperative cerebral arteriograms is limited because immediate postoperative changes tend to persist; that craniotomy is preferable to burr holes for removal of an acute hematoma; and that the value of cisternography, unless done serially, is limited since posttraumatic hydrocephalus develops rapidly and may persist indefinitely.

Acute Disease↗