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Biomedical subjects

J Henderson

Publications and source records attributed to J Henderson.

At least 199 records · Page 11Linked to original sources
PubMed1986

Occupation-related male infertility: a review.

Male infertility is a significant health problem for which few aetiological factors have been identified. The role of occupational exposure is largely unknown but certain substances such as 1,2-dibromo-3-chloropropane, oestrogen, heat, lead and microwaves have been reported to impair spermatogenesis in workers. Other agents which interfere with reproductive performance in experimental animals such as cadmium, manganese, organophosphates and some solvents have not been studied sufficiently for their occupational risks to be fully known. Some occupational exposures, extensively studied, appear to convey little or no risk to male fertility including radiological exposure, anaesthetic gases and Agent Orange. It is clear that the range of substances potentially hazardous to male reproduction is great but the number of agents for which the evidence is unequivocal is very small.

Anesthetics↗
PubMed1986

Association between occupational group and sperm concentration in infertile men.

The association between infertility and occupational group was examined using information collected from 1695 male patients. Although lack of detail in the nine occupational classifications may have diluted effects, mean sperm concentrations were significantly different, being highest in administrative and professional groups and lowest in farming and transport groups. Reported exposures to heat and chemicals were also significantly different between occupations. Greater occupational exposure to toxins may contribute to lower sperm concentrations in some groups such as farmers. More detailed research is needed to elucidate the association between occupation and infertility in men.

Adult↗
PubMed1985

Analysis of historical variables, risk factors and the resting electrocardiogram as an aid in the clinical diagnosis of recurrent chest pain.

A prospective study on 184 consecutive patients presenting with the chief complaint of recurrent chest pain (RP) for diagnostic coronary arteriography (CA) was conducted utilizing a simple questionnaire of historical, physical and electrocardiographic variables. A linear logistic regression analysis yielded a final data set of 13 variables. Concurrently, staff cardiologists who obtained the questionnaire data through direct questioning rendered a clinical diagnosis of either angina (coronary artery disease [CAD]) or noncardiac chest pain. Utilization of the regression analysis increased diagnostic accuracy from 69 to 86% (p less than 0.0003); sensitivity from 83 to 88% (NS) and specificity from 49 to 84% (p less than 0.0001). The best predictive variables for the presence or absence of obstructive CAD documented by CA were in order of decreasing value: age, electrocardiogram, pain aggravated by sex, sex (gender), pain aggravated by movement, diabetes mellitus, pain described as prickling, pain described as burning, pain relieved by rest, pain with radiation to both arms, associated nausea, associated dyspnea, and a history of a lipid disorder. Four variables were predictive of normal coronary anatomy (NCA), pain aggravated by movement, prickling, nausea, and dyspnea. Although this set of predictor variables may not apply equally well to all populations of cardiac patients, the availability and relative simplicity of the program allow for adding or deleting variables and thus provide for considerable potential in the diagnostic assessment of RP. An inexpensive pocket computer can utilize the coefficients generated by the logistic regression program to calculate the probability of CAD as the cause of RP.

Angina Pectoris↗
PubMed1984

Instant age-sex register.

An age-sex register for use in general practice was obtained directly from the family practitioner committee computer by direct transfer of data to a microcomputer.

Age Factors↗
PubMed1984

Play in the psychotherapy of selfobject relating.

Current literature dealing with narcissistic character disorder attempts to differentiate between mature relating with consensually validated whole objects and immature, more primitive relating with mirroring and validating selfobjects. In the latter case the object is especially valued for its role in buttressing a damaged or fragile self. The persistence into adult life of this more primitive relating to selfobjects can be viewed as a restitutive attempt, a healing by second intent. Through such a mechanism, attempts are made to make good deficits left by perceived failures of the primary object. These attempts include the setting up of relationships with figures whose empathic capacity is in some way sensed to be corrective, and the setting up of relationships with selfobjects which are in part created by the subject to provide himself with the kind of validating selfobject which has been longed for, yet never experienced. Winnicott conceives of transitional experience as an intermediate area allowed to the infant between primary creativity and objective perception based on reality testing. Transitional relating usefully clarifies the concept of selfobjects in emphasizing its common features with the transitional object. Transitional objects and selfobjects both contain the idea that the psychic apparatus is equipped with self-healing capacities. They tell us something about the nature of those self-healing capacities. The mental apparatus, as the physical apparatus, can attempt to heal itself in the face of injury or disease.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1983

What should be done about occupational accidents and diseases?

This paper argues that the perspective of economics is valuable in assessing the desirability, purpose and effectiveness of public intervention to reduce occupational accidents and diseases and suggests that the concept of efficiency provides one (although not the only) important criterion by which to judge policy in this field. Despite the incentives to adopt preventive measures that risk premia on wages in hazardous occupations will give to firms, it is argued that, without public intervention, these will be insufficient to bring down occupational accident and disease rates to their optimal levels. The paper then analyses the various methods by which the state might intervene in order to reduce these rates, such as by providing information on risks and stipulating legally enforceable standards, and suggests that a tax on employers for accidents and diseases that arise at work may also have advantages.

Accidents, Occupational↗
PubMed1983

Is incest harmful?

Classically, incest has been considered from both a psychological and sociological point of view to have harmful consequences. Genetic research, though by no means lacking controversy of its own, generally supports the notion that inbreeding has untoward genetic consequences. The psychodynamics of all three parties to father-daughter incest seem to indicate that people who become involved in incestuous behaviour are often psychologically damaged before the fact, so that if they show subsequent evidence of psychological impairment the incestuous behaviour can be as plausibly viewed as a dysfunctional attempt at solving problems as it can a cause of subsequent psychopathology. Girls involved in the father-daughter incest present in one of half a dozen frequent clinical syndromes. The presentation is influenced by the degree to which the girl may have participated in ongoing incestuous behaviour as opposed to being the presumed victim of an older adult's coercive actions or her own temporary suspension of a behavioural taboo. Research is inconclusive as to the psychological harmfulness of incestuous behaviour, and evidence is reviewed on both sides of this complicated and controversial question. Quite apart from the general issue of the harmfulness of incest, a number of indicators can be derived from the nature of the incestuous episode and the early response to therapeutic assessment which aid in the clinical forecasting of probable outcome.

Adaptation, Psychological↗
PubMed1982

Acute pancreatitis in identical twins.

Identical twins, 34-years-old at the time, developed abdominal pain of similar character while at a holiday resort. Both had drunk a greater amount of alcohol than usual, approximately eight 200-mL glasses of beer. The symptoms in one twin forced him to present to hospital where his plasma amylase level was found to be 2300 u/L. The other had the same symptoms, but did not present to hospital; however, when the symptoms later recurred, he also was found to have pancreatitis. Acute pancreatitis occurring simultaneously in identical twins has been reported only on one previous occasion.

Acute Disease↗