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J Hemet

Publications and source records attributed to J Hemet.

At least 91 records · Page 5Linked to original sources
PubMed1985

[Benign sub-periosteal osteoblastoma of the nasal cavity. histological and ultrastructural study of a case].

A case of periosteal benign osteoblastoma arising in the left nasal cavity is presented. The tumor develops on the surface of the middle turbinate without evidence of bone destruction. It has been locally excised and has not recurred in 3 1/2 years. The histological aspect is identical to that of the other cases of genuine osteoblastoma. The ultrastructure (the first of a periosteal osteoblastoma) is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular nuclei, abundance of well-developed rough-surfaced endoplasmic reticulum and numerous fine filaments. The osteocytes and osteoclasts basically resemble their normal counterparts. The final diagnosis of benign osteoblastoma rests at the light microscopy level. The differential diagnosis are reviewed. Distinguishing histologic and ultrastructural characteristics between this tumor and other benign osteoblastic tumors are discussed.

Cell Nucleus↗
PubMed1984

Cavitation of mesenteric lymph nodes, splenic atrophy, and a flat small intestinal mucosa. Report of six cases.

This study describes, in 6 patients with a flat small intestinal mucosa and splenic atrophy, a particular lesion of the mesenteric lymph nodes termed "cavitation." In 4 women and 2 men with abdominal mass, intestinal obstruction, or suspected celiac disease-associated lymphoma, unusual pseudocystic lymph node lesions were found in the jejunal or jejunoileal mesentery. These lesions consisted histologically of a large central cavity occupied by hyaline-type material and surrounded by fibrous tissue and remnants of lymph node structures. There was no histologic evidence of malignant lymphoma or mesenteric panniculitis. Diffuse subtotal villous atrophy involving at least the jejunum was found in each case, together with unequivocal biological and morphological evidence of splenic atrophy, severe malabsorption, and a history of chronic or childhood diarrhea. HLA B8 or DR3, or both, was present in 4 of 4 cases; dermatitis herpetiformis was present in 1 case. An unequivocal mucosal response to a gluten-free diet was observed in 2 cases. Four patients died of cachexia or hyposplenism-related infections. We conclude that cavitation of mesenteric lymph nodes is an original feature which may be associated with splenic atrophy and a flat small intestinal mucosa; some of these patients may have celiac disease. Pathogenesis is unknown.

Adult↗
PubMed1983

[Massive digestive hemorrhage in typhoid fever. A case report].

In a case of massive intestinal haemorrhage during typhoid fever the bleeding area was located by angiography to the superior mesenteric artery, and excision of the ileo-colonic junction was performed. Pathological study of the lesions showed necrosis of Peyer's plaques resulting in section of small submucosal arterioles. The necrosis itself was caused by initially endothelial lesions, later completed by thrombosis. The complication is exceptional. This case is reported in order to draw attention to the usefulness of mesenteric arteriography and the effectiveness of surgery in massive intestinal haemorrhages.

Colonic Diseases↗
PubMed1983

Comparative nephrotoxicity of four aminoglycosides: biochemical and ultrastructural modifications of lysosomes.

In 1982, aminoglycosides still are widely prescribed and considered indispensable for the treatment of severe gram-negative infections. All the aminoglycosides are nephrotoxic, but both experimental works and clinical investigations indicate that they do not all have the same nephrotoxic potential. Within the renal tubular cell in several animal species and in man, the initial and the most extensive changes are those that occur in the lysosomes. We compared the effects of gentamicin, tobramycin, netilmicin and, amikacin on (a) lysosomal structural latency, (b) the activity of several enzymes, either lysosomal or those contained in the proximal tubular cell brush border, and (c) the accumulation of myeloid bodies in the lysosomes. From our results, it appears that gentamicin is the aminoglycoside that induces the greatest number of lysosomal changes whereas amikacin induces the least, with the effects of netilmicin and tobramycin quite close to those of amikacin. Other works comparing the nephrotoxicity of aminoglycosides reveal the same high nephrotoxic potential of gentamicin.

Amikacin↗
PubMed1980

Sarcoidosis. Retroperitoneal fibrosis, renal arterial involvement, and unilateral focal glomerulosclerosis.

In one patient with pulmonary sarcoidosis, hypertension occurred during the course of the disease. Aortography showed extensive narrowing of the right renal artery. Surgical exploration disclosed extensive periaortic and perirenal fibrosis. This fibrosis encircled the right renal artery and caused extrinsic compression. Pathological examination disclosed a large amount of histiocyte epithelioid infiltration in various samples of the fibrosis and particularly in the adventitia of the renal artery, highly suggestive of sarcoidal angiitis. Surgical biopsy was performed on both kidneys. The right kidney, protected by arterial stenosis, was little altered, while the left kidney showed extensive interstitial, tubular, and glomerular lesions. The glomerular lesions were focal and segmental hyalinosis.

Adult↗
PubMed1979

[Neonatal segmental small intestine dilatation. Unusual form of necrotizing enteritis?].

The authors report two new cases of segmental dilatation of the small bowel at birth. In the pathological intestinal areas, they describe inflammatory alterations similar to neonatal necrotizing enteritis, and some particular lesions of the myenteric plexus with a deterioration of the ganglionic cells. It is suggested that such lesions might have a certain responsibility in the etiology of chronic idiopathic pseudo-obstruction syndrome.

Dilatation, Pathologic↗
PubMed1978

[Anatomopathological introduction to the study of chondrocalcinosis].

Although the macroscopic aspects of chondrocalcinosis easily permit diagnosis, the morphological analysis of the basic lesion--the crystalline microgeode--raises the problem of the relationship between chondrocalcinosis and the chondrocyte lodge and arthrotic lesions. According to studies with the optical and electron microscope, the crystalline precipitate of calcium pyrophosphate in the basic cartilaginous substance always appears distinct from the chondrocytes, but in its vicinity the chondrocytes are often altered by degenerative lesions. There appears to be no relationship between arthrosis and chondrocalcinosis of frequency alone is considered.

Chondrocalcinosis↗
PubMed1977

[Respiratory function disorders during hepatopathies with immunity involvement].

A respiratory functional test was done systematically on 24 patients with chronic hepatitis and was found normal in only 2 cases. It showed an alteration of the transfer in 14 patients and a syndrom of hyperinflation in 8 others. Despite the histopathological proof it seems that the transfer alteration could be attributed to diffuse interstitial pulmonary lesions. They have already been noted in chronic hepatitis by several authors. The pathogeny of this interstitial involvement probably implied immunity phenomenons including the participation of the antigen Australia or others. As for the hyperinflation syndrome observed in 4 patients in the absence of any bronchopulmonary history, it could reveal an emphysema, which, so far, had not been seen associated to chronic hepatitis.

Adult↗