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Biomedical subjects

J Heinrich

Publications and source records attributed to J Heinrich.

At least 199 records · Page 11Linked to original sources

[Breast asymmetry--differential diagnosis and surgical correction].

The problems of asymmetry of the female breast have been exemplified on four cases. Changes in a single breast due to anatomical defects or as a result of an accident, as well as changes due to a large fibroadenoma have been presented. Surgical correction was made after an individual evaluation of each case and included reduction mammoplasty, breast augmentation, lifting and nipple transplantation or reconstruction.

Adolescent↗

[Chronic pollution with environmental toxins: formaldehyde].

Formaline is a colourless, strongly odoriferous gas. It is a very important basic component in chemical industry. It has become well known as a poison in residential areas due to its appearance in chipboard panels. Formaline causes a variety of acute and chronic toxic stress symptoms. In many cases the relation of formaline exposition and symptoms is difficult to demonstrate. The main keys to diagnosis are a very careful anamnesis and the cumulated appearance of symptoms. We intend to show several possible sources of stress symptoms caused by formaline, as well as diagnostic possibilities. This includes several methods of diagnostic assessing formaline concentration in the air, and several suggestions for the reduction of formaline emission.

Air Pollution, Indoor↗

[Differential diagnosis of papillomas in the area of the genitals].

Infection of the genital organs by human papillomavirus (HPV) is the most commonly diagnosed sexually transmitted disease. Papillomaviruses lead to a contact infection of the epithelium and present with different clinical and histological signs. With the exception of the best known clinical manifestation Condylomata acuminata, subclinical infections can be only diagnosed from a stepwise examination. Physiological results from both men and women may be falsely explained as being caused by viruses, and can lead to an incorrect therapy. Genital papilla (Papillae coronae vulvae et glandis) present as atavistic cutaneous papilla a normal situation but with functional significance. Differences in clinical symptoms as well as the possibilities of further differentiation can be obtained by means of pictures taken during colposcopy.

Condylomata Acuminata↗

A potentialgradient-conductivity-scanner for the investigation of effects leading to buoyancy-driven convection on continuous-flow-electrophoresis.

Continuous flow electrophoresis (CFE) is a mild and high-resolving method for the separation of sensitive biomolecules like peptides and proteins. The resolution is decreased by several effects, of which density gradients are important since they lead to buoyancy-driven convection. A tool for the measurement of physical quantities that cause the separation process, a potentialgradient/conductivity-scanner has been developed. With this PC-scanner consecutive potential- and concentration profiles can be measured inside the CFE-chamber. Local current densities and local joule heat yielding density gradients are calculated from the measurement data. With the PC-scanner the influence of gravity on separations by CFE can be evaluated more easily by the knowledge of the thermal and electrical conditions inside the separation slit.

Biotechnology↗

[Immunotherapy of urinary tract infections].

In the discussion on prevention of urinary tract infection, interest is now centered on virulence factors of microorganisms and immunological defense mechanisms of the host organism. In this article current research results and the clinical aspects of an immunological treatment method for urinary tract infection are summarized and discussed.

Animals↗

[Tooth health and periodontal condition in adults with and without root caries].

In a population sample of 2261 men and women aged between 35 and 74 years the prevalence of root caries increased for both sexes consistently with age and ranged between 49 and 73%. In the mean 1.8 to 2.9 teeth were affected. Subjects with root caries had fewer teeth, more teeth with untreated coronal caries, and more teeth which needed conservative treatments. The number of extractions required was the same in subjects affected by root caries. In the age older than 65 years subjects affected by root caries had more teeth in the average of 2 teeth and significantly more fillings in their teeth. If a DMF/T-index of 15 to 19 was recorded nearly half of all subjects were affected by root caries. In individuals with root caries lesions aged between 35 and 54 years significant severe periodontal disease were seen.

Adult↗

Relationship of lipoprotein(a) to variables of coagulation and fibrinolysis in a healthy population.

In the Prospective Cardiovascular Münster (PROCAM) study, serum lipoprotein(a) [Lp(a)] and its relationship to pro- and anticoagulatory as well as fibrinolytic indices were determined in a large group of employees: 864 men (m) and 373 women (f), ages 16-65 years. Univariate statistical analysis showed Lp(a) concentration to be associated with fibrinogen concentrations in both sexes (m: r = 0.08, P less than 0.05; f: r = 0.20, P less than 0.001), but not with euglobulin fibrinolysis activity, tissue-type plasminogen activator, plasminogen activator inhibitor type 1 (PAI-1), or the split products of cross-linked fibrin (d-dimer). In women only, Lp(a) was significantly correlated with antithrombin III (r = 0.15, P less than 0.01) and Protein C (r = 0.17, P less than 0.01). Further sex-related differences were seen in the relationship between Lp(a) and age (m: r = 0.05; f: r = 0.23, P less than 0.001) and body mass index (m: r = 0.01; f: r = 0.19, P less than 0.001), primarily as a consequence of remarkable differences of Lp(a) concentrations between postmenopausal (mean = 79.4 mg/L) and premenopausal women (mean = 51.5 mg/L, P = 0.001). Multiple-regression analysis demonstrated a significant negative correlation of Lp(a) to PAI-1 (m: beta = -0.12, P less than 0.01; f: beta = -0.14, P less than 0.05) and a positive correlation to cholesterol (m: beta = 0.18, P less than 0.001; f: beta = 0.17, P less than 0.01) and systolic blood pressure (m: beta = 0.08, P less than 0.05; f: beta = 0.11, P less than 0.05).

Adolescent↗

[Will root caries become a treatment problem of the future?].

Based upon the present prevalence of root caries an attempt is taken to evaluate the future importance of this carious type. A population sample of 2,261 men and women aged 35 to 74 years were examined. The participation rate was 81%. Root caries was recorded when the lesion was obviously soft and located on cementum. The prevalence of root caries increased for both sexes almost consistently with age and ranged between 49 and 73%. In the mean 1.8 to 2.9 teeth were affected. Root caries was found more often among men than women. Over the sixth decades the reduction of the relative frequency of root caries was stated. Up to this age the rates of tooth extraction were higher than the rates of incidence. If it succeeded that in the future aged people will retain more teeth than nowadays a increase of root caries can be expected.

Adult↗

[Kininase II (SACE) and renin in sarcoidosis patients and healthy probands in exercise testing].

Over a period of three years, we investigated the behaviour of renin and kininase II in 26 patients with active, histologically confirmed sarcoidosis in comparison with healthy test subjects, during ergometer exercise. Renin activity was determined radioimmunologically, and kininase II by means of spectral photometry (Cushman-Lieberman method). In both groups, a significant increase in renin and kininase II during the course of exercise on the ergometer was observed, which, however, was more marked in the sarcoidosis group of patients. Furthermore, the activities of both enzymes were highly significantly elevated as compared with the group of healthy subjects in each individual phase of exercise. In addition--if we consider the average values of the two enzymes in each of the individual subjects--it would seem possible in most cases to correctly ascribe the person involved to the group healthy subjects or patients, in particular when the average values of renin and kininase II obtained as described above, are multiplied together.

Exercise Test↗

[Mullerian adenosarcoma].

The Müllerian adenosarcoma is an extremely rare entity of tumours of the group of the Müllerian and mesodermal mixed tumours. This tumour seems to be a malignant transformation of the uterine papillary cystadenofibroma. The periglandular malignant transformation of the stromal component and the benign glandular structures are typical signs of the Müllerian adenosarcoma. In accordance with references the prognosis of the adenosarcoma is better than those of other Müllerian mixed tumours. The demonstrated cases warn against undervalue.

Aged↗