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Biomedical subjects

J Hein

Publications and source records attributed to J Hein.

At least 109 records · Page 6Linked to original sources
PubMed1977

[Comparative radiological and morphological study of the human pancreas. 2. Morphometrical investigation of the human pancreatic duct system (author's transl)].

The diameter and the thickness of all the side ducts were measured in 27 normal or nearly normal human pancreata. The obtained data (about 5,000 pairs of Figures) were evaluated statistically. The relative thickness of the walls increases with growing distance from the papilla as well as with the reduction of the diameter of the side ductes. Beyond the age of fifty the diameter of the ducts is 10--13% higher than in younger age. In a logarithmical system there is a strong correlation between the diameter and the thickness of the side ducts, slightly diminished with aging. The regression coefficient is slightly diminished with aging. But the variance of the wall thickness in respect to the diameter of the ducts shows such a rise with aging, that the number of ducts with relatively thick and small walls increase with aging. By reason of the logarithmic system the positive variance has a higher weight. Therefore periductal fibrosis increases with aging.

Adolescent↗
PubMed1976

[Changes of the pancreatic duct system associated with aging: their relations to parenchyma (author's transl)].

A postmortem study by ductography and histology was carried out in 50 macroscopically normal human pancreata. The alterations of the pancreatic duct system, their relations to the parenchyma, and their changes depending on age were studied. The most frequent changes of the ducts are epithelial hyperplasia (88%) and periductal fibrosis (74%). In the ducts they produce cystic widening (62%) and intraluminal protein precipitates (40%), within the parenchyma an intralobular fibrosis up to total fibrosis of lobules (88%). All these alterations increase with aging both in frequency and intensity. But they are already visible before the age of 50 and sometimes before the age of 30. The pathogenetic connexions between the changes of the duct system and the alterations of parenchyma were studied by serial sections and ceroplasty. This investigation revealed that the small branches of the larger ducts, which drain small periductally situated lobules, play an important role in the development of the parenchymal alterations. No connections were found between the pancreatic alterations and diseases of the bile duct system.

Adult↗
PubMed1975

[Inhalations with L-arginine in the treatment of cystic fibrosis (author's transl)].

12 patients were treated with L-arginine hydrochloride 1-3 times per day for a period of 4 till 8 weeks. All children had been in control in our hospital longer than one-year. The patients received beside administration of digestant enzymes and vibration massages, inhalations with N-acetylcystein (Mucosolvin). The frequency of the daily inhalations was not changed. We compared the results of clinical, x-rays scintigraphic and laboratory investigations during the period of N-acetylcysteine treatment and after the administration of L-arginine. The mucolytic effect by L-arginine is much less than by N-acetylcystein.

Adolescent↗
PubMed1972

[Not Available].

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Anatomy↗