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Biomedical subjects

J Handa

Publications and source records attributed to J Handa.

At least 199 records · Page 11Linked to original sources
PubMed1982

[Spinal extradural haematoma--the cause of the bleeding (author's transl)].

A case of spontaneous spinal extradural haematoma is reported in an 18-year-old male patient. Neither hypertension nor haemorrhagic diathesis was found as a possible cause of bleeding. A conglomerate of abnormal vessels was removed at operation, and histological examination showed the appearance of venous racemose angioma. Reviewing the available literature, 85 cases of spontaneous spinal extradural haematoma have been reported. Twenty-five of them were 20 years of age or younger, and the histological confirmation of angioma as a cause of bleeding was obtained in only five. Nevertheless, an angioma should be seriously suspected as a possible cause of spontaneous spinal extradural haematoma, particularly in the young.

Adolescent↗
PubMed1982

[Total myelography with metrizamide through the lumbar route (author's transl)].

Total myelography with metrizamide at a concentration of 270 mgI/ml was carried out via lumbar puncture in 170 consecutive patients. Good opacification and/or diagnostic value was obtained in the lumbar, thoracic and cervical region at 88.8%, 77.6% and 72.4% respectively. Unsatisfactory results were mostly due to the poor technique of physicians and x-ray technicians. Also it was inadequate to perform this study in some lesions, such as ruptured arterio-venous malformation and occification of posterior longitudinal ligament. Several cases with previous oil myelography showed poor results, because the remaining of Myodil disturbed a good spreading of the newly injected media. It was requested to evacuate oily contrast media prior to metrizamide myelography. One of the most important clues to a successful myleography was to make dilusion of contrast media as little as possible, and the use of high concentration of metrizamide (250-270 mgI/ml) seemed to be tolerated. It was also important to avoid excessive movement of the patient and the rapid transit of the contrast media to the level of interest. It was recommended to study the entire spinal subarachnoid space as a whole. In sixty-three patients out of 170, one or more abnormal myelographical findings were detected at unexpected level. Immediately after the examination the patients were encouraged to drink a large quantity of diuretic beverages such as tee, juice or coffee for the purpose of reducing side effects. As Potts and coworkers and Eldevik and associates reported, it was recognized that the overhydration could reduce the severe side effects after the metrizamide myelography.

Adolescent↗
PubMed1981

Computed tomography of intracranial epidermoid tumours with special reference to atypical features.

Intracranial intradural epidermoid tumours have been known to show characteristic CT features consisting of non-enhancing lucent lesions with sharply defined margins that are often irregular and scalloped. Since the epidermoid tumours are benign, potentially curable lesions, it should be also noted that they may occasionally show atypical CT features such as dense lesion, definite marginal enhancement following contrast medium injection, or tumour associated with large, heavy calcifications. Four such atypical cases are reported, and the literature is reviewed.

Adult↗
PubMed1981

[Solitary spinal epidural angiomas-reports of three cases with special reference to spinal epidural hematoma (author's transl)].

Solitary spinal epidural angiomas are rare. Of 114 cases of spinal angiomas reported in a recent monograph of Pia and Djindjian, only twenty-nine were angiomas locating exclusively in the spinal epidural space. We have recently experienced such a spinal epidural angioma in 3 patients. One of them, aged 18, developed transverse spinal syndrome, and a venous angioma was found at operation as the cause of bleeding. Reviewing the available literature, we could find only 7 such cases with an angioma confirmed by histologic study as a source of spontaneous spinal epidural hematoma. All but one were young patients aged 19 or more. In patients with spinal epidural hematomas, particularly those in youth, vascular malformations should be seriously suspected as a cause of bleeding.

Adolescent↗
PubMed1981

[Giant neurofibroma of the occipital scalp associated with lambda defect-case report (author's transl)].

Calvarial bone defect associated with a hugh neurofibroma in the region of the lambdoid suture was reported in a 42-year-old man with v. Recklinghausen's neurofibromatosis. An enlarging occipital tumor was first noted at age 4 similar to or approximately 5, and an operation was performed at age 12. Lambda defect was noted at that time, but the operative diagnosis was, apparently, "meningocele". Available literature was reviewed, and the significance of calvarial bone defect in the region of the lambdoid suture as a manifestation of v. Recklinghausen's disease was stressed. Lambda defect witn no sclerosing margin, particularly if associated with hypoplasia of the ipsilateral mastoid cells, has been known to represent the primary nature of the bone defect due to mesodermal dysplasia. In the present case, plain radiographs of the skull revealed abnormal sclerotic change around the bone defect. It is suggested that such an osteoblastic change may well indicate the secondary nature of the bone defect due to the presence of overlying neurogenic tumor.

Adult↗
PubMed1980

Agenesis of an internal carotid artery: angiographic, tomographic and computed tomographic correlation.

Congenital absence of one internal carotid artery was found by angiography in a woman of 52 years who had subarachnoid hemorrhage. The absence of the bony carotid canal on the affected side substantiated the congenital nature of this rare vascular anomaly. We believe this to be the first report of absence of the bony carotid canal and the intracavernous portion of the internal carotid artery confirmed by computed tomography and cavernous sinography.

Carotid Artery, Internal↗
PubMed1980

Amenorrhea-galactorrhea syndrome with craniopharyngioma.

Two cases of craniopharyngioma presenting with amenorrhea-galactorrhea syndrome due to hyperprolactinemia are reported. After operation and irradiation, the tumor reduced markedly in size. Coincidental decrease in plasma prolactin level and restoration of menstruation seem to support the view that the hypothalamic prolactin inhibiting factor (PIF) had played an important role in hyperprolactinemia in these two patients.

Adult↗
PubMed1980

[Computed tomography in leptomeningeal and ventricular spread of primary brain tumors (author's transl)].

Of 8000 consecutive patients studied with computed tomography, 10 patients with primary intracranial tumors (germinoma, medulloblastoma, malignant teratoma and glioblastoma) showed ventricular or leptomeningeal spread of the tumor cells. In patients with leptomeningeal spread, computed tomography showed obliteration of basal cisterns and sulci with isodense or slightly hyperdense mass, which was markedly enhanced following administration of the contrast medium. In cases of ventricular spread, a narrow zone of high density was noted on the ependymal surface, and it was also markedly enhanced with the contrast medium. Similar CT scan appearance of contrast enhancement in the subarachnoid space or in the ventricular surface was, however, noted also in the infectious processes such as basal arachnoiditis or ependymitis, and the differentiation of the neoplastic process from the infectious lesions seemed impossible based on the CT scan appearance alone.

Adolescent↗
PubMed1980

[Multiple cerebral tuberculomata involving brainstem and cerebellum--report of a case (author's transl)].

A case of multiple cerebral tuberculomata involving the pons and cerebellum was presented. The lesions were demonstrated by CT as isodense to slightly dense foci. All four intra-axial lesions showed homogeneous enhancement following an intravenous injection of the contrast medium, and one of them was surrounded by a small area of low density, probably representing the perifocal edema. The patient responded well to chemotherapy with streptomycin, hydrazid and rifampicin : cranial nerve signs and long tract signs clearing rapidly and the enhancing lesions and mass effect on CT disappearing concomitantly. Although cerebral tuberculoma is nowadays very rare in Japan, still a high index of suspicion should always be entertained during the investigation of patients showing solitary or multiple enhancing lesions with no or slight degree of perifocal edema on CT, and a trial of antituberculous drugs should be given before the incurable malignancy is presumed or the lesion is explored surgically.

Brain Diseases↗