Search PubMed⌕ Search

Biomedical subjects

J Haller

Publications and source records attributed to J Haller.

At least 163 records · Page 9Linked to original sources

[Real-time sonography of the skull in the newborn].

The results of 293 examinations of the skull by sonography in 170 newborn are presented. In 73 patients the results could be compared with the findings on CT or at post mortem. In 48%, abnormal sonograms of the skull were obtained, due to congenital abnormalities, hydrocephalus or intracerebral bleeds. High accuracy and wide application make real time sonography the diagnostic procedure of first choice for the examination of the brain of the newborn. An attempt has been made to determine the optimum time for the examination and suitable intervals for follow-up.

Agenesis of Corpus Callosum↗

[Mirizzi syndrome: a sonographic diagnosis?].

The ultrasound appearances of 11 patients with operatively confirmed Mirizzi syndrome have been analysed. The trio 'dilated intrahepatic bile ducts, concretions in the neighbourhood of the dilated common hepatic duct with a normal distal duct' permit the diagnosis of the Mirizzi syndrome with considerable certainty. In five patients these features were found by sonography and no other diagnostic procedure was necessary. In six patients, ERC was carried out in order to evaluate the distal common bile duct. In one case PTC was carried out, since the liver hilum could not be seen on sonography.

Bile Ducts, Intrahepatic↗

Testicular hormones and intermale aggressive behaviour in the presence of a female rat.

A hypothesis was examined that increased levels of available testicular hormones are responsible for the increased aggressiveness of males in the presence of a female. In the first of two experiments intact male rats were injected with the androgen antagonist flutamide before exposure to oestrous, dioestrous or no females. Consistent with the hypothesis, flutamide-injected males were less aggressive than the respective control males which had been injected with oil alone. Yet the antiandrogen did not fully block the increased aggressiveness between males exposed to an oestrous female. In experiment 2 the aggressive behaviours of male rats in the presence of an oestrous female were observed after castration and restoration therapy with different amounts of testosterone propionate (TP). Neither a physiological amount (200 micrograms) nor an unusually large amount (800 micrograms) to TP could adequately mimic the effects of a gonadally intact male exposed to a sexually receptive female. These data suggest that differences in androgens available to target tissues influence aggressiveness among males exposed to a female. However, there are other factors involved, presumably the chronic morphological-physiological-behavioural changes that are provoked by copulatory experience.

Aggression↗

Imaging techniques and renal infections.

Newer techniques have supplanted the urogram as the preferred procedure for evaluation of several renal infections. When imaging is indicated in acute pyelonephritis, sonography should be performed first. In focal pyelonephritis, sonography and/or computed tomography are preferred. These techniques are also generally required for elucidation of renal abscess and pyonephrosis.

Abscess↗

[Primary aspergillosis of the lung in leukoses].

The course, radiological features and pathological changes of primary aspergillosis in four patients with acute lymphatic leukaemia are described. Two patients died despite antimycotic therapy. Breakdown of the infiltrate could not be established radiologically, nor pathologically. In a further two patients, a 'primary aspergilloma' developed during the course of several days. Both patients survived. The radiological demonstration of a fungus ball and of an air crescent in a typical aspergilloma can be regarded as a good prognostic sign.

Adult↗

Sexual experience, androgens and female choice of a mate in laboratory rats.

Sexual experience produces long-lasting changes in both the behaviour and reproductive system of a male rat. The response of the female rat to an area that had recently housed a previously mated male was investigated in three experiments. In experiments 1 and 2 females preferentially urine marked in an area vacated by a sexually experienced (SE) male relative to areas vacated by a sexually inexperienced (SI) or castrated (C) male. The density of female marks were ranked SE greater than SI greater than C greater than empty area. In experiment 3 female preference of an SE male with varied and multiple mating experiences was magnified when compared with an SI male. There was the suggestion that the multiple SE male was even preferred to a male with only a single mating experience. A fourth experiment demonstrated an acute increase in circulating testosterone in multiple SE males exposed to oestrous or non-oestrous females, and the increase was observable for up to 7 days after exposure to an oestrous female. The conclusion is that chronic changes in androgen-dependent urinary by-products released by the SE male mediate the discrimination and choice of a mate by the female rat.

Animals↗

Female rats prefer an area vacated by a high testosterone male.

In each of 4 experiments, female rats were observed as they moved freely about an apparatus that had recently housed 2 males. The androgen levels of the males were manipulated with castrations and exogenous injections of testosterone propionate (TP). For the most part, female exploration times in the areas vacated by the 2 males did not differ. The urinary markings over the urine from the males, however, did differ. The female exhibited a decided marking preference for the area that had housed the male with higher titers of androgens. The preferences were for intact vis-a-vis castrated males, though injections of TP restored the castrates' attractiveness to the females. When both males possessed reproductive levels of TP, the females preferred to mark over the urine of the male with the higher levels of the androgen. The reproductive advantage for the female may be the choice of a mate with more viable sperm, because androgens are intimately involved in spermatogenesis.

Animals↗

[Pulmonary complications in hepatic coma].

Incidence and extent of pulmonary complications were evaluated retrospectively in 101 patients with hepatic coma (34 patients with acute liver failure, 57 patients with hepatic encephalopathy and 10 patients with mixed forms). 76 patients (73.3%) had pulmonary complications (pulmonary edema 57 cases, pneumonia 20 cases, tracheobronchitis 30 cases). Lethality of the group with pulmonary complications was 97% as compared to 16% in the group without pulmonary complications. Pathogenesis of pulmonary complications is not completely clear; different mechanisms are being discussed like central mechanisms, vascular lesions caused by metabolic or toxic factors, cardiac failure, and increased susceptibility to infection. In 9 out of 59 cases (15.3%) with respiratory failure no morphological changes could be observed in the lungs; in these cases intrapulmonary shunts might have been the cause for the pulmonary complications. The incidence of pulmonary complications increased by a factor of 2.4 during intensive care unit treatment of the patients; this increase shows, that intensive care unit treatment still has to be improved.

Adult↗

Intracranial pressure monitoring in Reye's syndrome.

The neurologic damage caused by rapidly rising intracranial pressure can be halted or reversed only if specific therapy is instituted early. The key to such successful management is continuous monitoring by either subarachnoid bolt or ventricular cannula. Indications and techniques for monitoring are outlined, as is a ventricular cannula. Indications and techniques for monitoring are outlined, as is a step-by-step approach to management of intracranial hypertension as it develops.

Brain Edema↗

Renal anomalies in fetal alcohol syndrome.

Six patients with fetal alcohol syndrome were found to have developmental abnormalities of the kidney. In only one patient was investigation for renal pathology made in the absence of clinical indication. Two had palpable masses in the left upper quadrant, one had pyelonephritis, one had painless hematuria, and the fifth patient had symptomatology suggestive of renal failure. Although the renal pathology was not of the same type in all cases, it is of interest that four patients had either unilateral or bilateral renal hypoplasia.

Abnormalities, Multiple↗

[The diagnostic value of mammography during pregnancy and lactation (the radiological features of the breast during pregnancy) (author's transl)].

During early and late pregnancy and lactation, there is an increase in the size of the breasts, with increased density of their structure. The moderately dense parenchyma in young women is characterised by a) wavy contours of the subcutaneous zone and b) linear or oval translucencies in the central parenchyma. Our investigations indicate that it usually takes three months after delivery before the breast structure returns to normal and one is able to interpret the mammogram satisfactorily. For this reason mammography should be avoided during these three months and if there is a suspicion of disease in the breast, a biopsy should be carried out immediately.

Adolescent↗