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Biomedical subjects

J Guillaume

Publications and source records attributed to J Guillaume.

At least 37 records · Page 2Linked to original sources
PubMed1980

Lipid and energy metabolism in chicks affected by dwarfism (dw) and Naked-neck (Na).

In two experiments, sister pairs of chicks, one dwarf (dw) and one nondwarf (Dw+), were reared in individual cages to 5 weeks of age. Chicks carrying the sex-linked recessive dw gene were identified at hatching by the closely linked fast feathering gene (k). The dwarf chicks showed a 27% reduction in weight gain, a reduced body temperature, increased carcass content of lipid, and increased lipid 14C activity from injected 14C-labeled acetate. The augmented accumulation of carcass lipid in the dwarf chicks was shown to be a result of increased lipogenesis and decreased energy expenditure. An autosomal dominant gene for naked-neck (Na), present in half of the pairs of chicks, also caused increased lipogenesis. Naked-neck birds showed increased energy expenditure in a cool environment and perhaps a greater flexibility of body temperature regulation. An interaction between the dw and Na genes was apparent under cool environmental conditions and may have been due to a suppression by the dw gene of the Na gene's effect on thermoregulation, possibly by slowing down lipid degradation.

Animals↗
PubMed1978

[Dorsal medullary compression in vertebral hyperostosis].

The authors present two observations of dorsal medullary compression by intraspinal benign osseous proliferations developing in subjects who present with anterior vertebral hyperostosis. In the second observation operative intervention confirmed the site and nature of the lesion. The authors have researched the same radiological findings in other cases of vertebral hyperostosis. They describe the lesions which are of considerable practical importance as they are able to injure the spinal cord and the nerve roots, resulting in a hyperostotic dorsal myelopathy. All unexplained paraplegias should be investigated for such lesions by meticulous tomographic studies.

Adult↗
PubMed1978

[Pseudo-tumoral softening of the cerebellum].

The author establish an onerall picture of cerebellar infarction with brain stem compression after reviewing 63 cases published in the literature and 4 personal observations. The frequency of this affection can be compared with that of cerebellar hematomas. Diagnosis is based on its predominance in males, the early age at which it appears, its rapid and typical onset, and the delayed signs of brain stem compression. Conventional neuroradiological procedures show an expanded cerebellar volume, and the scanner can specify the ischaemic nature of the lesion. As soon as changes in consciousness occur surgical decompression is necessary, first by external drainage of C.S.F. and later, if necessary, by direct access to the postdrior fossa.

Adult↗
PubMed1977

[Benign intracranial hypertension due to thrombosis of a transverse sinus. Diagnosis by scintigraphy using bleomycin labelled with cobalt 57 (author's transl)].

In a case of benign intracranial hypertension with no apparent aetiology, cerebral scintigraphy demonstrated abnormal uptake in the left transverse sinus 24 hours after injection of the isotope. This sinus was seen to be thrombosed by cerebral angiography. On the basis of this case, the role of cerebral venous thrombosis in cases of "pseudo-tumor cerebri" is discussed.

Adult↗
PubMed1977

Experimental embolization with inflatable and releasable balloons in dogs.

Experimental arterial occlusion was performed on eight dogs by means of inflatable and releasable balloons, in five of which a reliable and long lasting arterial occlusion was obtained. Three accidents occurred. One dog died when the liquid latex was emptied spontaneously from the balloon and the territory was embolized causing a severe general reaction. In two other dogs the emptying of the balloon, inflated with iodine, was followed by distal embolization of the empty latex balloon. The possibility of such accidents would be too great a risk for human application, but it now seems possible with the new glue, isobutyl-2-cyanoacrylate, to embolize vascular territories more accurately and more safely by means of inflatable and releasable balloons.

Animals↗
PubMed1976

Congenital spondylolysis of cervical vertebrae with spondylolisthesis anf frontal narrowing of the spinal canal. Report of two cases.

Two cases of cervical spondylolisthesis, due to a congenital defect in the pars interarticularis of C6, associated with spina bifida and elongation of the contralateral pars interarticularis, are reported. Tomography showed an abnormal direction of the articular facets of C6 and demonstrated a narrow frontal diameter of the cervical spinal canal at the level of the malformation. Gas myelography showed a slight compression of the cord. Unlike previously reported cases the patients had neurological findings which, in one case at least, were certainly referable to the spinal cord.

Adult↗
PubMed1975

Studies of the energy and protein requirements of the growing guinea-fowl.

1. Guinea-fowl of both sexes and female chickens were fed from 1 to 12 weeks on diets the energy concentration of which was constant at either 2-6, 2-9 or 3-2 Mcal/kg (10-8, 12-1 or 13-4 MJ/kg) while the calorie to protein ratios were changed, for some groups, from 124 to 157 or 200 at 4 and 8 weeks. 2. Guinea-fowl, but not chickens, were unable to overconsume when the protein concentration was low with the result that the body fat content was not reduced when the protein concentration was increased. 3. In the second trial the ME level of the diets was fixed at 12-6 MJ/kg while the protein content was varied, from 21 to 28% in the diets fed to 6 weeks of age and from 15 to 24% in those fed from 6 to 12 weeks. 4. It is concluded that for the growing guinea-fowl the diet should contain 12-6 MJ ME/kg, the protein concentration reducing from 24 to 26% in the period 0 to 4 weeks to 19 to 20% in the period 4 to 8 weeks and to 16% or less in the period 8 to 12 weeks.

Animal Feed↗