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Biomedical subjects

J Grellet

Publications and source records attributed to J Grellet.

151 records · Page 9Linked to original sources
PubMedDate not supplied

[Ureteral manifestations of collagen diseases (author's transl)].

Ureteral lesions are rarely observed during the course of collagen diseases, and when they do occur, are specific localizations of these disorders. Diagnosis is made by intravenous urography. This usually demonstrates uni- or bi-lateral segmentary stenoses that may be calcified, with the lesions being most frequently present in the lumbar region. In rare cases there is dilatation of the "necklace of pearls" type. The stenosis usually increases in severity, especially when corticotherapy is reduced, and resection of the affected ureteral segments may be necessary.

Adolescent↗
PubMedDate not supplied

[Pelvic lymph node groups in computed tomography. Topographic atlas].

This atlas was prepared to facilitate the diagnosis of lymph mode enlargement in the pelvic region and to improve topographic diagnosis. Fifty computed tomographies were performed after lymphography using centimetric pelvic slices in order to select eight levels for reference. A statistical analysis was conducted to establish a diagram of the mean number of lymph nodes on the right and left side for each level. A table was established indicating the mean number and standard deviation for each group of nodes for the 8 different levels. In addition, a control slice (chosen among 50) accounts for the morphology of the iliac vessels, of the lymph nodes and psoas muscle most frequently encountered at each level. The distribution of the groups of nodes shows why interpretation can be difficult, particularly at vessel bifucations and confluents. Precise morphology based on effective opacification, especially in the pelvic area, is required for positive and especially topographic diagnosis. Finally, the description of the medial border of the psoas muscle and its close relations with certain groups of lymph nodes can cause some problems because of the similar densities. The atlas is of great help here.

Anatomy, Regional↗
PubMedDate not supplied

[Pharmacokinetic and clinical evaluation of rectal hydrophilic gel of methohexital in pediatric surgery].

The purpose of the study was to develop and to test a new form of rectal systemic gel for methohexitone administration in children undergoing minor surgery. Pharmacokinetics of methohexitone were determined in children following intravenous or intrarectal administration either at low or therapeutic dosage. Anaesthesic efficacy of this gel was performed in 11 patients receiving a therapeutic dosage (25 mg/kg). Pharmacokinetics of methohexitone appears independent of both dosage and route of administration in children. The bioavailability of the rectal gel appears sufficient to provide efficient clinical plasmatic concentrations. As a consequence of the rapid and good resorption of methohexitone from rectal lumen and of the low variability of plasmatic concentrations, a rapid and reliable sedation was observed in all patients. The clinical anaesthesic efficacy of the rectal hydrophilic gel associated with the absence of an apparent local intolerance and important side effects, make this new form suitable for methohexitone administration in children.

Administration, Rectal↗
PubMedDate not supplied

[Ambulatory preparation for double contrast enema. Retrospective study involving 100 nonhospitalised patients (author's transl)].

The authors present a technique of preparation for double contrast barium enema, using the oral route only. It was used in 100 consecutive, suitable non-hospitalised patients with the following results: colonic empyting was perfect in 64% of cases, satisfactory in 25% and inadequate in 11%. Tolerance was deemed to be good. The authors do not suggest that the technique should be used in hospitalised patients, often proving inadequate under such circumstances.

Barium Sulfate↗