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Biomedical subjects

J Grellet

Publications and source records attributed to J Grellet.

At least 109 records · Page 6Linked to original sources

[The preponderant role of the radiologist in the prevention of recto-colonic carcinoma by the detection of polyps (author's transl)].

The adenomatous polyp is considered to be the precursor of recto-colonic carcinoma. The detection of polyps would appear to be ensured with maximum effectiveness by double contrast barium enema and the authors recommend the routine use of this technique for this purpose. The aim of the radiologist should no longer be merely that of the diagnosis of carcinoma of the colon and rectum, but also its prevention by enabling colonoscopic excision of glandular polyps.

Colonic Neoplasms↗

[Lymphography in chronic lymphocytic leukemia (author's transl)].

Sixty-seven lymphangiograms were performed in 58 patients with chronic lymphocytic leukemia. These patients were classified according to a new anatomico-clinical staging system which has previously been shown to bear prognostic significance. The lymphangiograms were divided into four groups on the basis of lymph node size and each group was further divided into subgroups (12). Each subgroup corresponded to a different roentgenographic picture. A good correlation was observed between lymphangiographic and anatomico-clinical staging: lymphangiogram groups 3 and 4, anatomico-clinical stage III and IV (p less than 0.001). The absence of normal lymph nodes in all patients, the diversity of lymphangiographic appearance from one patient to another and even the diversity from one region to another in the same patient should be stressed.

Adult↗

[New cases of familial generalized cortical hyperostosis with dominant transmission (Worth's type) (author's transl)].

A case of two families with a total of 5 cases of generalized cortical hyperostosis of the cortex of the long bones is clinically latent. It is not accompanied by any osseous fragility and is usually discovered by chance. Mandibular hypertrophy can occur but is not constant. It must be differentiated from the recessive form described by Van Buchen, which is more severe and involves extensive and progressive osteocondensation which can lead to paralysis of the cranial nerves. The small number of cases published (23) leads one to suppose that its diagnosis is frequently missed, undoubtedly because it is mixed up with a minor form of osteopetrosis.

Adult↗

[Diagnosis at arteriography of parathyroid adenomas. 45 cases (author's transl)].

The authors report the results of parathyroid arteriography in 45 patients in whom diagnosis was certain, with surgical confirmation of the radiological findings in 44. In this group arteriography led to the exact localisation of the parathyroid adenoma in 21 out of 34 cases. The angiographic signs of parathyroid adenomas are not constant and a negative arteriogram under no circumstances eliminates the possibility of an adenoma being present. In addition, the angiographic signs do not all possess the same significance, some being merely suggestive without definitely indicating the presence of an adenoma. By contrast, when there were highly suggestive or definite signs at arteriography, an adenoma was found surgically at the expected site in 21 of 22 cases. Finally, the authors stress the importance of comparison of the results of arteriography and thyroid scan in order to eliminate thyroid adenomas, as well as the necessity of a photographic substraction involving the different phases of the arteriogram, since this may reveal adenomas invisible on standard arteriography films.

Adenoma↗