[Spinal puncture in the bacteriological diagnosis of bacterial spondylitis. Experience in the rheumatology departments of Reims, Clermont-Ferrand and Rouen].
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Biomedical subjects
Publications and source records attributed to J Gougeon.
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In three cases of rheumatic spondylitis, fracture across the disc of an ankylosed spinal segment (C5-C6, D7-D8, and D12-L1 respectively) resulted in rapid development of a discopathy with destruction of the adjacent vertebral bodies. In one of these cases, surgical exposure of the focus permitted anatomical study of the lesion; the changes that had developed after the fracture were inflammatory in appearance, which at first suggested infection by non-specific micro-organisms, an assumption that was rapidly abandoned. This misleading histological appearance largely explains why these destructive discopathies in spondylitis have long been regarded as a consequence of the rheumatic process itself. A review is presented of the arguments which suggest that they have, in fact, a mechanical pathogenesis, often determined by a fracture. From this it may be concluded that the treatment of choice is temporary immobilization in moderate cases and surgery with transplantation in complicated or unstable cases.
The authors report 3 new cases of femoral nerve paralysis complicating anticoagulant treatment. The first sign was pain, the neurological signs occurred later and the patient usually recovered but recovery was sometimes incomplete. The pathogenesis is not clear : a muscle hematoma, ischemia of the nerve trunk, and intraneural hemorrhage are the commonest theories.
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Although the number of synthetic anti-inflammatory agents is ever increasing, it is apparent that most of these drugs have been administered orally or rectally. Because it can be given parenterally, ketoprofen is of additional interest. Furthermore, tolerance of the product by the intramuscular route is adequate even in patients likely to suffer side-effects when the drug is given orally.
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Lesions of the middle and lower part of the cervical spine during rheumatoid arthritis are less frequent than those of the cervico-occipital joint. They concern the discs on the one hand, the posterior inter-apophyseal joints, on the other hand. The authors report a case of rheumatic spondylodiscitis of C5-C6 with dislocation, complicated by quadriplegia, and review other published cases of rheumatoid lesions of the middle and lower cervical spine with neurological complications. The mechanisms of these lesions and their complications are then discussed.
Clinical, laboratory, and radiological data do not make possible a certain diagnosis of infectious spondylitis: errors are thus possible, even frequent, and are harmful to the patient. In order to ensure a certain diagnosis and to avoid exploratory surgery as far as possible, the authors propose systematic needle puncture of the inververtebral disk--a technique that is simple and inoffensive to carry out in all disks below T4, and that, in a series of 18 cases, gave a success rate of 2 out of 3 (11 positive results). The technique, the results and the factors essential for success are described and analysed.
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