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Biomedical subjects

J Gaillard

Publications and source records attributed to J Gaillard.

At least 127 records · Page 7Linked to original sources
PubMed1980

Bone-forming cell line derived from embryonal carcinoma cells.

The use of established cell lines of various types has provided information on the properties of certain stem cells and on the conditions of their differentiation. No bone-forming cell line has so far been described. We report here the isolation, from in vitro differentiating teratocarcinoma cells, of a line which, on subcutaneous injection into syngeneic mice, gives rise to ossicles. The appearance of ossicles is preceded by the formation of a cartilaginous matrix, thus reproducing what has been described as endochondral differentiation. The ossicles obtained are rapidly colonized by host marrow, are non-malignant and stop growing 2 weeks after injection of the cells. In certain conditions, however, osteosarcomas, chondroosteosarcomas and fibrosarcomas can be obtained. From these tumours, cell lines have been isolated which retain in vitro the properties of the cells found in the tumour.

Animals↗
PubMed1980

[The surgical treatment of scar tissue stenosis of the crico-tracheal junction (author's transl)].

On the basis of 6 personal cases, the authors report the special conditions associated with surgery for stenosis of the crico-tracheal junation : proximity of the recurrent laryngeal nerves, difficulty of accurately matching the upper and lower ends, difficulty in passage of the suture materials. They nevertheless conclude that in the treatment of stenosis at this level of the respiratory tract, resection-anastomosis would appear to give better results than those obtained by Rethi's operation. Alongside major surgery, minor therapeutic techniques and, in particular, the laser used endoscopically also have a role to play : either in the treatment of moderate stenosis, or in the prevention and treatment of recurrent stenoses after resection-anastomosis.

Cicatrix↗
PubMed1980

[Interest of pleurectomy as a complement of emphysematous bullae resections (author's transl)].

Complementary pleurectomy following emphysematous bullae resection is justified only if it improves long-term results in comparison with surgical symphysis obtained by pleural irritation. This cannot be proved at this time. On the other hand, in spite of their limitations, experiments in man suggest that this pleurectomy does not cause any particular complications. In the animal, this parietal pleural resection causes cortical fibrous alveolitis which is not present after other symphysis processes. The authors suggest therefore the use of pleurectomy as a complement of bullae resections in acute and diffuse emphysema.

Acute Disease↗
PubMed1979

[Not Available].

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Contraception↗