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Biomedical subjects

J G Marks

Publications and source records attributed to J G Marks.

At least 73 records · Page 4Linked to original sources
PubMed1980

Contact urticaria and allergic contact dermatitis to benzocaine gel.

A 39-year-ole man developed edema and vesiculation of the oral mucosa following the application of benzocaine (Hurricaine) gel. Open testing demonstrated an immediate urticarial reaction. Closed patch tests were positive after 48 hours. The contact dermatitis was consistent with a delayed-type hypersensitivity. It appears, however, that a nonimmunologic mechanism caused the contact urticaria since passive transfer was negative.

Adult↗
PubMed1980

Linear nevus sebaceus syndrome.

The linear nevus sebaceus syndrome, a neurocutaneous disorder, is characterized by anomalies of ectodermal and mesenchymal structures. We briefly describe the diagnostic features and management of this condition in a 2-year-old child.

Child Development↗
PubMed1980

Treatment of tinea nigra palmaris with miconazole.

A patient with tinea nigra palmaris was successfully treated with 2% miconazole nitrate cream. In vitro studies demonstrated sensitivity of the causative agent, Exophiala werneckii, to this antifungal agent.

Adolescent↗
PubMed1980

Granuloma fissuratum masquerading as a skin tumor.

Granuloma fissuratum is a reactive process of the skin usually caused by chronic trauma from ill-fitting eyeglass frames. Its clinical resemblance to malignant tumors makes it important to recognize this benign condition. This case report discuses the diagnosis and management of granuloma fissuratum.

Diagnosis, Differential↗
PubMed1978

Atopic dermatitis, eczema herpeticum, infectious mononucleosis, and depressed cell-mediated immunity.

An immunologic investigation was undertaken in a patient with atopic dermatitis and infectious mononucleosis complicated by eczema herpeticum. Humoral immunity was normal. The cell-mediated immune (CMI) response was temporarily depressed during the acute phase of the illness as measured by in vivo skin tests, and in vitro tests using T-lymphocyte population, macrophage inhibition factor, and lymphocyte transformation. It is postulated that the depression of CMI caused by infectious mononucleosis precipitated the development of eczema herpeticum in this patient.

Adult↗
PubMed1978

Darier's disease: an immunologic study.

Darier's disease is frequently complicated by bacterial skin infections and occasionally by Kaposi's varicelliform eruption. Postulating that defective host immunologic competence might explain these infections, humoral and cell-mediated immunity (CMI) were evaluated in four patients. Humoral immunity was normal as demonstrated by quantitative immunoglobulins, isohemagglutinins, direct skin immunofluorescence, and B-cell counts. The CMI was evaluated by standard delayed type hypersensitivity skin tests, T-cell counts, lymphocyte transformation assays, macrophage inhibition factor (MIF) assays, and skin windows. Blunted lymphocyte blastogenesis, MIF, and skin window response indicated depressed CMI. Polymorphonuclear leukocyte chemotaxis and phagocytosis were normal.

Adolescent↗
PubMed1978

March cellulitis.

Explore the source record for details and available documents.

Cellulitis↗
PubMedDate not supplied

Changes in lymphocyte and Langerhans cell populations in allergic and irritant contact dermatitis.

We observed in situ changes in lymphocyte subpopulations and Langerhans cells during allergic and irritant contact dermatitis using immunohistochemical staining methods with monoclonal antibodies to cell surface antigens. In both types of contact dermatitis, there was a perivascular infiltrate of T lymphocytes, with helper/inducer T cells predominating. B cells were absent, and natural killer cells were absent or sparse. During the course of allergic contact dermatitis, Langerhans cells showed a striking sequential change in location, with the cells first in the epidermis, then perivascularly in the dermis (days 1-14), and returning to the epidermis (days 14-21). In irritant contact dermatitis, the Langerhans cells were initially identified in the epidermis and then appeared diffusely in the dermis (days 1-2). The numbers in the dermis then decreased abruptly (day 4). They were again identified in normal numbers in the epidermis (day 21). The response of Langerhans cells appears to be different between allergic and irritant contact dermatitis.

Antigens, Surface↗
PubMedDate not supplied

Occupational skin disease in hairdressers.

Irritant or allergic contact dermatitis of the hands is the main occupational hazard for hairdressers. The shampoos, dyes, and waving solutions that must be applied by hairdressers are the agents involved. There is a significant association between the development of occupationally induced hand dermatitis and a history of atopy, particularly atopic dermatitis.

Beauty Culture↗