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Biomedical subjects

J G Lane

Publications and source records attributed to J G Lane.

At least 37 records · Page 2Linked to original sources

Is dentition an accurate indication of the age of a horse?

It is widely accepted that the age of a horse can be determined from an examination of its teeth, but there is no evidence that the accuracy of the systems of ageing used has been validated. A dental record was made of 80 horses of known age. There was a good correlation between the actual and apparent age of the horses up to five years, but older horses showed much greater variability and accuracy declined markedly after 11 years of age. The disappearance of the 'cup', but not the 'mark', proved to be one of the more reliable features. The average age at which the dental star appeared was one to two years earlier than usually stated. The occlusal angle of the incisors and Galvayne's groove were useful indicators of age, but the caudal upper incisor hook was observed in horses of practically any age over six years.

Age Determination by Teeth↗

The ligamentization process: a 4 year case study following ACL reconstruction with a semitendinosis graft.

This study evaluates the histological and biochemical changes that occurred in a semitendinosis autograft 4 years after intraarticular placement as an anterior cruciate ligament (ACL) substitute in a human patient. The graft was harvested during total knee replacement. Comparison to harvested ACL and hamstring tendon was made. Changes in collagen crimp pattern, cell type, glycosaminoglycan composition, and collagen crosslinking were present between the ACL autograft and the hamstring tendon. The appearance and biochemical properties of the semitendinosis autograft and the native ACL were similar 4 years following intraarticular placement. These observed phenomena could be attributed to functional adaptation, supporting the concept of ligamentization.

Adaptation, Physiological↗

Arthroscopic staple capsulorrhaphy: a long-term follow-up.

Fifty-four shoulders with recurrent anterior shoulder instability were evaluated following arthroscopic staple capsulorrhaphy. Average follow-up for those with only the index surgery was 39 months. Eighteen patients (33%) experienced at least one episode of postoperative instability. Ten underwent an open reconstructive procedure. Routine radiographs at time of follow-up demonstrated loose staples in 15% of asymptomatic patients. Range of motion was preserved following surgery. There was no loss of forward elevation. An average of 5 degrees of external rotation and one spinal segment in internal rotation were lost following surgery. Forty-three percent of overhead athletes were able to return to their preinjury level of activity. Caution should be taken when considering arthroscopic staple capsulorrhaphy as recurrence rates are higher than those following open reconstruction. However, range of motion and functional level are well-maintained. When capsulorrhaphy is performed, consideration should be given to routine staple removal following adequate capsular healing.

Adult↗

Evaluation of some prophylactic therapies for the idiopathic headshaker syndrome.

Eighteen horses affected by the idiopathic headshaker syndrome were studied in an owner assessed trial to test the efficacy of some prophylactic therapies. Riding the affected animal with a veil over the nostrils gave varying degrees of temporary relief in three of 10 horses. Local (intra-nasal) corticosteroid therapy was reported to be slightly effective in three of nine horses, but treatment with sodium cromoglycate, systemic corticosteroid, flunixin meglumine and an antihistamine were generally ineffective. Bilateral infraorbital neurectomy provided sustained relief in three of seven horses, but in one of these cases, a reaction at the neurectomy site necessitated another surgical procedure after six months. A fourth horse was reported to be slightly improved after neurectomy. A period of nasal irritation resulting in self-inflicted trauma was a common complication of this surgery.

Administration, Inhalation↗

Inflammatory middle ear disease of the dog: the clinical and pathological features of cholesteatoma, a complication of otitis media.

During a study of inflammatory middle ear disease in the dog cholesteatoma was found to accompany otitis media in seven of the 62 ears examined (11 per cent). The clinical, radiological and pathological findings in these animals imply that cholesteatoma in the dog is an aggressive lesion which must be differentiated from uncomplicated otitis media.

Animals↗

Inflammatory middle ear disease of the dog: the pathology of otitis media.

Inflammation within the middle ear cavity was recognised in 62 of the ears of 42 dogs with chronic otitis externa and otitis media, after biopsy or necropsy of the middle ear. The pathological changes in the middle ear resembled those reported in other species or after the experimental induction of otitis media in dogs. Perforations in the tympanic membrane were rarely found; on the contrary, the membrane was often thickened. However, the question of whether a perforation in the tympanic membrane must occur before otitis externa can extend to otitis media was not resolved.

Animals↗

Tracheal obstructions in two horses and a donkey.

The clinical signs associated with intramural tracheal obstructions in two horses and a donkey were respiratory distress and coughing, which were aggravated by exercise and excitement. The obstructions were at the level of the thoracic inlet and consisted either of flattening of the cartilage rings in the dorsoventral plane or of cartilage rings having a scroll-like conformation. They appeared to be developmental in origin and to have been present for a considerable time before the onset of clinical signs. Endoscopy and radiography were helpful in the diagnosis of the condition.

Airway Obstruction↗

Pyarthrosis of the knee. Treatment considerations.

Patients with pyarthrosis of the knee can be effectively managed by several different methods. A retrospective review of patients with the diagnosis of septic arthritis of the knee was undertaken to determine the efficacy of two different treatment programs. Multiple-needle arthrocentesis was contrasted with formal arthrotomy drainage. In this series, patients with a longer than three-day history of a knee pyarthrosis and those with Staphylococcus aureus or enteric gram-negative organisms on culture benefited from open drainage procedures in lieu of repeated aspiration techniques.

Adolescent↗

Developmental cysts in the upper neck of Anglo-Nubian goats.

Five young Anglo-Nubian goats were found to have developed a fluid-filled cyst in the upper neck. In each case the cyst was unilateral and after excision was found to be lined in most sites by non-ciliated, pseudostratified columnar epithelium, containing goblet cells. This epithelium closely resembled that of normal parotid salivary gland ducts. The lesions did not recur in any of the four goats followed-up after surgery.

Animals↗

Neoplasia involving the middle ear cavity of dogs.

Eleven cases of neoplasia which involved the middle ear cavity of dogs are recorded. Eight of the tumours originated in the external ear canal and comprised four adnexal tumours, one squamous papilloma and three adenocarcinomas of the ceruminous glands. Papillary adenomas were recognised within the middle ear cavity of two dogs. In one animal the precise origin of an anaplastic carcinoma involving the middle ear could not be determined. Only five of the tumours were amendable to surgical excision and four dogs survived for more than eight months after surgery.

Adenocarcinoma↗

An evaluation of tympanometry, otoscopy and palpation for assessment of the canine tympanic membrane.

Three techniques for the assessment of the integrity of the canine tympanic membrane were evaluated experimentally. Tympanometry, an objective technique, was shown to be very accurate for the evaluation of the integrity of the ear drum. Otoscopic examination by experienced personnel was shown to be moderately accurate under controlled conditions when the external ear canal was not inflammed. However, under field conditions when otitis externa was present, visual inspection of the tympanic membrane was seldom possible even after lavage of the ear. Palpation of the tympanic membrane with a blunt probe was shown to be very inaccurate and led to rupture of the tympanic membrane in a high proportion of cases. These results imply that two widely used techniques for the examination of the canine tympanic membrane are unsatisfactory. Furthermore, they suggest that previous reports of the prevalence of ear drum perforations in dogs may need reappraisal. Tympanometry is a non-invasive, objective and practical technique for the assessment of ear drum integrity which is worthy of further evaluation.

Acoustic Impedance Tests↗

Pneumonia, lung abscesses and pleuritis in adult horses: a review of 51 cases.

Case records are reviewed of 51 adult horses in which a diagnosis of pneumonia, pulmonary abscess or pleuritis had been made. Forty-five horses were afflicted with pneumonia and/or pulmonary abscesses; in 11 of these the infection was primary, whereas in 34 it was secondary to another disease process (inhalation of food or saliva, thoracic trauma, generalised infection, airway disease, neoplasia or thromboembolism). Of the 11 horses with primary pulmonary infections, 10 appeared to be associated with a previous episode of stress; this took the form of long distance travel in eight cases. There was a statistically significant association between primary pneumonia and/or lung abscesses and the use of the horses, with the highest incidence in showjumpers. Eighteen horses had pleuritis, of which 12 were secondary to pneumonia or pulmonary abscesses, two to thoracic trauma and one to generalised avian tuberculosis. Three cases of primary pleuritis were identified.

Animals↗