Search PubMed⌕ Search

Biomedical subjects

J Friberg

Publications and source records attributed to J Friberg.

At least 55 records · Page 3Linked to original sources
PubMed1986

Intrauterine inseminations with washed human spermatozoa.

The success of intrauterine inseminations with washed human spermatozoa was evaluated in four groups of patients. The first two groups were couples in whom either the man or the woman had detectable circulating sperm-agglutinating antibodies. The third group included couples where the woman exhibited hostile or absent cervical mucus, whereas the fourth group represented couples with oligozoospermic males. The couples underwent 3.7 +/- 2.1 insemination cycles, with a 30% overall pregnancy rate for all four groups. Intrauterine inseminations of women with hostile cervical mucus yielded a 68% conception rate. Couples with either male or female serum sperm-agglutinating antibodies showed 25% and 40% pregnancy rates, respectively. However, none of the couples with oligozoospermic males achieved pregnancy. Intrauterine inseminations with washed human spermatozoa thus represent a satisfactory method of achieving pregnancy in women with hostile cervical mucus and in couples with circulating sperm agglutinating antibodies. Couples in whom oligozoospermia has been identified as the principal cause of infertility do not seem to benefit from this therapy.

Adult↗
PubMed1986

Transcervical balloon tuboplasty.

TBT is a new technique that by use of a balloon catheter technique in a fashion similar to that of balloon angioplasty allows reestablishment of tubal patency in selected cases of tubal occlusion. The case presented here describes the first transcervical dilatation and recanalization of a proximally occluded fallopian tube in a patient with infertility.

Adult↗
PubMed1986

A new stirrable catheter for gamete intrafallopian tube transfer (GIFT).

Cannulation of the fimbriated end of the fallopian tube during gamete intrafallopian tube transfer (GIFT) may be at times extremely difficult and even require minilaparotomy. An ideal laparoscopic GIFT catheter should be flexible and stirrable, have a small diameter, and yet be sturdy enough to enable its manipulation. Such a catheter was developed in collaboration with Cook Ob/Gyne, a Division of Cook Inc., Indiana, with primary emphasis on easy laparoscopic manipulation. Its use in eight attempts of GIFT resulted in three pregnancies (37%).

Catheterization↗
PubMed1985

IgM gammopathy and the lupus anticoagulant syndrome in habitual aborters.

Recent reports strongly suggest an association between a laboratory picture of autoimmunity in the absence of clinical signs and symptoms and the recurrence of spontaneous pregnancy loss. This association seems particularly strong when circulating lupus anticoagulant is present and has therefore been called the circulating lupus anticoagulant syndrome. We present four patients with this syndrome who in addition to the asymptomatic autoimmune laboratory picture were also found to exhibit a distinct IgM gammopathy. In view of earlier reports that implicated IgM in poor pregnancy outcome, particularly in association with systemic lupus erythematosus, it is suggested that all patients with circulating lupus anticoagulant syndrome be evaluated for an IgM gammopathy. A fraction of IgM may be detrimental to development and growth of the normal fetal placental unit and may thus be implicated in repeated early pregnancy loss.

Abortion, Habitual↗
PubMed1985

High-dose human menopausal gonadotropin therapy for successful ovulation induction for in vitro fertilization in perimenopausal women.

Five women with elevated gonadotropin levels were treated with high doses of human menopausal gonadotropin (hMG) in order to induce an ovulatory response. Three of the five patients did not show any increase in circulating estradiol levels nor any change in the size of follicles (as observed by ultrasound), even after prolonged stimulation with up to 1200 IU of hMG. Two patients achieved an ovulatory response, however. They underwent laparoscopy with successful oocyte retrieval and fertilization. Both patients had evidence of pregnancy: one showed a transient hCG rise (chemical pregnancy), while the other continued to 12 weeks' gestational age when fetal demise was diagnosed.

Adult↗
PubMed1985

Nonspecific urethritis in men.

The epidemiology, diagnostic criteria, and etiology of nonspecific urethritis in men are discussed. Microbiological examinations have indicated that in the vast majority of these patients Chlamydia trachomatis and Ureaplasma urealyticum are the main causes for the disease. Treatment of the disorder has centered on the use of tetracyclinelike drugs, and with proper treatment cure can be obtained in the majority of patients.

Chlamydia Infections↗
PubMed1985

Sonographic imaging of intrauterine adhesions.

Hysterosalpingography and hysteroscopy are the diagnostic modalities most commonly used to evaluate and follow intrauterine adhesions (Asherman syndrome). Three patients with intrauterine adhesions are presented. These adhesions were visualized with sonography and appeared as dense intrauterine lines. These lines disappeared after hysteroscopic lysis of the adhesions. The present results indicate that sonography may alert the clinician to the presence of intrauterine adhesions.

Adult↗
PubMed1985

Diagnosis of genital Mycoplasma and Ureaplasma infections.

Genital Mycoplasma and Ureaplasma have been implicated in pelvic inflammatory disease, puerperal infections, septic abortions, low birth weight, nongonococcal urethritis and prostatitis as well as spontaneous abortion and infertility. An unequivocal diagnosis of infection with these organisms can be made only after properly obtained specimens have been evaluated with the use of selective cultures.

Female↗
PubMed1984

Inhibition of the human tissue plasminogen activator in plasma from different species.

The rate and extent of complex formation between protease inhibitors present in plasma from different species and a human plasminogen activator purified to homogeneity from the supernatant of a human melanoma cell line was studied in vitro. The fibrinolytic activity of the one-chain plasminogen activator disappeared form human, cat and rabbit plasma with a half-life of 100 minutes. By means of antibodies directed against purified protease inhibitors the main inhibitor in human, cat, dog and rabbit plasma was identified as alpha 2-antiplasmin. Alpha 2-macroglobulin and C1-esterase-inhibitor functioned as inhibitors to a lesser extent. The main inhibitor in rat plasma was alpha 2-macroglobulin. The plasma half-life was 3 (rabbit and human) to 10 (dog and rat) times shorter for the two-chain form than for the one-chain form of the plasminogen activator molecule. It is also concluded that, with respect to plasma elimination of the fibrinolytic activity, among the common laboratory animals, the rabbit is the most suitable animal available for the study of fibrinolysis.

Animals↗
PubMed1984

Lymphocyte subsets in endometriosis.

Recent investigations suggested a possible immunologic etiology for endometriosis. To determine whether cellular immunity may be affected in patients with endometriosis, peripheral lymphocyte populations were investigated in 31 confirmed endometriosis patients and 22 control patients. No statistical differences in OKT3, OKT4, OKT8, OKM1, and OKTa1 cells could be observed. Total lymphocyte numbers were within normal ranges for both groups. Helper/suppressor ratios were not statistically different and were in a normal range for both groups. It is concluded that numeric differences in lymphocyte subpopulations represent only a very unlikely contributing factor in a potential immunologic etiology of endometriosis.

Antibodies, Monoclonal↗