Search PubMed⌕ Search

Biomedical subjects

J Franke

Publications and source records attributed to J Franke.

At least 199 records · Page 11Linked to original sources
PubMed1976

Physical properties of fluorosis bone.

The bones of two patients, one with a moderate and one with a severe chronic industrial fluorosis (stage I-II and stage III), and the bones of three control persons were examined. The following parameters were determined: the fracture load, the fracture load/unit area (resistance to pressure) of the body of the first lumbar vertebra, the bending strength of the neck of the femur and of the lower third of the femur, the fracture load/unit area and the modulus of elasticity of femoral slices 2 cm thick and of precisely defined cylinders from the femoral cortex. The microhardness according to Vickers on the cross section of the femur was also determined. The results obtained are discussed with regard to fluoride therapy of osteoporosis.

Bone and Bones↗
PubMed1976

[Scan microscopic investigation of human industrial fluorosis (author's transl)].

We examined the bones of 3 people in various stages of industrial fluorosis. Scan microscopic studies were conducted on the periosteal surface and the fracture surfaces of ribs, tibia and vault of the cranium. In the mild form of fluorosis, we found slight swelling and impregnation with globular and crystalline material in the periosteal collagenous fibers. The impregnation and swelling increases and, in severe cases of fluorosis, an irregular orientation of abnormal fine fibers and thick deposits on the bone surfaces occurs. The radiating fibers of muscle and tendon insertions were apparently mineralized first. Atypia of the bone collegan was found which involved the collagenous fibers, the basic substance and their mineralization as well as the ossification process itself. The scan microscopic findings were compared with the normal histology for fluorosis and discussed.

Aged↗