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Biomedical subjects

J Flament

Publications and source records attributed to J Flament.

At least 91 records · Page 5Linked to original sources

[Evaluation of macular functional capacity by helium-neon laser interferometry].

We describe the principles of the measure of visual acuity by using the laser interference retinometer. Interference fringes are projected on the retina, with variation of direction and thickness varied, to study the functional capacity of the macula. This method is particularly useful in patients with cataracts, because it is much less influenced by the clarity of the media than Snellen chart listing. We give the results of a series of 122 eyes with cataract, comparing pre-operative laser acuity and post-operative Snellen visual acuity. The pre-operative interfermometric measure is possible in 77% of the cases, but in most cases of mature cataract or dense posterior subcapsular opacities, the patients do not discern any interference fringes. In immature cataracts according to other results of the literature, post-operative Snellen visual acuity reaches preoperative laser acuity in 60% of the cases, and is better in 29% of the cases. Clinical conditions such as macular degeneration, cystoid macular oedema, amblyopia, visual field cuts through fixation or myopic choroïdopathy, may make the interferometer test unreliable.

Cataract↗

Ultrastructural demonstration of retrovirus antigens with immuno-gold staining in prodromal acquired immune deficiency syndrome.

The peripheral lymphocytes of a patient with prodromal acquired immune deficiency syndrome contained giant multivesicular bodies. These were specifically stained by immuno-gold labelled polyclonal antibodies against the major core protein p24 of bovine leukaemia virus and human T cell leukaemia virus I. Moreover, the patient's serum was positive for bovine leukaemia virus by the ELISA method.

Acquired Immunodeficiency Syndrome↗

[Urrets-Zavalia syndrome and glaucomatous cataract. Etiopathogenic and nosologic discussion].

After penetrating keratoplasties for different congenital or acquired corneal diseases, the presence of characteristic cataracta glaucomatosa lens opacities was noted in 9 cases of fixed, dilated pupil iris atrophy of Urrets-Zavalia. This association--rarely mentioned in the literature--is an opportunity to study again the different physiopathological theories on this syndrome (pupillary block by mydriasis with hypertony, upsetting of iris neurovegetative balance, particular sensitivity of ocular tissues to the surgical aggression in keratoconus), to analyze their arguments, and the preventive measures that proceed from them. The almost complete extinction of this type of complication of the corneal graft surgery, since the routine use of these preventive measures, proves the multifactorial origin of this syndrome.

Adolescent↗

[The annular scotoma and jack-in-the-box phenomenon in aphakia corrected with eyeglasses. Experimental approach].

An experimental study of "annular scotoma" was conducted. Variations in prismatic effects at the boundary of the lens with respect to incidence were evaluated with the aid of a laser beam. The use of an arc-perimeter and an artificial aphakic eye allowed reconstruction of light beam paths from the outside to the inside of the eye. The results obtained enabled a more rigorous analysis of this optical phenomenon. A straightforward formula obtained from the experiment (tan theta = b/a) provided better understanding of the variations generated by certain parameters. This same formula can be applied to the mechanism of the "Jack-in-the-box" phenomenon.

Aphakia, Postcataract↗

[Remanent efficiency of timolol in ocular hypertension (author's transl)].

In four ocular hypertensive patients (seven eyes) the lowering of intraocular pressure to a normal level persisted over a period of several months after gradual cessation of topical Timolol therapy. This remanent efficiency ("after-effect") could be used in treating ocular hypertension in order to prevent glaucoma damage.

Adult↗