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Biomedical subjects

J Feit

Publications and source records attributed to J Feit.

At least 37 records · Page 2Linked to original sources

Effect of cyclophosphamide on the course of cutaneous wound healing.

The healing process of cutaneous wounds has been followed with the aid of mechanical tests, autoradiographic investigation of fibroblastic reaction in the wound and method of electron microscopy. Cyclophosphamide has been found not to have any substantial effect on the favorable course of healing of the surgical wound, hence, surgical intervention combined with postoperative administration of Cyclophosphamide does not jeopardize the healing process.

Animals↗

Localization of alpha-fetoprotein in liver tissue of rats during postnatal development: comparison of the immunofluorescent and autoradiographic methods.

Localization of alpha-fetoprotein has been followed in the liver of rats of the Wistar strain from birth up to 37th day of life, and its presence was detected by means of the immunofluorescent and the autoradiographic methods. The former has shown alpha-fetoprotein to be localized in hepatocytes and the number of positive hepatocytes to decline proportionally with that of alpha-fetoprotein concentration in the serum. In newborn rats almost all the hepatocytes were found to be positive. During the course of the subsequent development of the liver tissue the number of positive hepatocytes decreases and at the time of the formation of the lobular structure only certain groups of lobes remain positive. The number of positive cells, gradually diminishes from the periphery towards the vena centralis. The autoradiographic method revealed only small groups of individual cells to be alpha-fetoprotein positive, without any specific localization.

Animals↗

Diffusion through the vessel wall of transmitter released by sympathetic stimulation. A fluorescence and Autoradiography study.

The disposition of sympathetic transmitter within the wall of rat femoral and rabbit saphenous arteries has been studied during sympathetic stimulation. Using a histochemical fluorescence technique, sharply delineated bead-like fluorescent spots representing sympathetic nerve terminals were found at the adventitio-medial junction. In specimens excised during sympathetic nerve stimulation, the entire media was veiled by fluorescent material representing noradrenaline which had diffused into that layer after release. The localization of the nerve terminals in controls as well as diffusion of transmitter during stimulation in the rat femoral artery was corroborated by autoradiography of tritiated noradrenaline.

Animals↗