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Biomedical subjects

J F Muir

Publications and source records attributed to J F Muir.

142 records · Page 8Linked to original sources
PubMed1977

[Variations in gas exchange and hemodynamic effects of various means of oxygen administration (spontaneous ventilation, controlled ventilation and under I.P.P.B.) in 19 severely obstructed pulmonary hypertension patients].

In 19 cases of severe chronic respiratory insufficiency by obstruction, the authors studied the haemogasometry and haemodynamic incidence of inhaling a mixture with FiO2 by various ways and in respiratory reeducation. Controled ventilation with or without manual abdominal pressure, instrumental kinesitherapy under pressure relaxor and simple oxygen inhalation. The pressure relaxor seems particularly suited to patients suffering above all from hypercapnia and obstruction because of its limited haemodynamic repercussions.

Adult↗
PubMed1977

[Rehabilitation of chronic pulmonary patients. Critical study of objectives and methods. Current state of the problem].

Having given a definition of chronic pulmonary patients and of readaptation by reference to the W.H.O. and to the results of an international survey and the study group of the special Unit of the European Society of respiratory Physiopathology, the authors report a critical study of the conception and the present aims of readaptation. They successively present the therapeutical, medico-social and psychological aspects of readaptation, the different techniques used today, and summarize the present functioning of Europeans centres of readaptation. Finally they draw the main lines of a program of readaptation with the public health scheme and envisage the problems of organization and functioning.

Chronic Disease↗
PubMed1977

[Elements to be taken into consideration in the establishment and supervision of respiratory rehabilitation programs].

For a good respiratory re-education, the handicap must be analyzed together with its causes and mechanisms, in relation with the patient's social environment, his age and profession. The handicapping factors should be analyzed in a medico-social (pollution, weather) and medical context by detecting the affection involved and the functional analysis. The latter is deduced from the clinical signs and measurements defining the functional syndrome justifying an appropriate treatment. The importance of the handicap is drawn out of the clinical measures of maximum effort studied by ergometry. There are 2 levels of handicap (without alteration of blood gases at rest) and of respiratory insufficiency: simple or complicated by decompensation bouts enabling the choice of re-adapatation methods correlated with age an environment. Clinical and functional supervision as well as the study of the integration in the environment, form the basis of the analysis of results obtained in 2 comparable groups or in one homogeneous group subjected first to a simple medical treatment, then to re-adaptation.

Humans↗
PubMed1976

[CT 1341 in continuous administration in 75 cases of prolonged general anesthesia in odontostomatology (constant flow assured by a double-lumen venous catheter and electric perfuser)].

The authors used during 75 prolonged general anaesthesia in maxillo-facial surgery CT. 1341 (Alfatesine) administered pure at constant flow rate through a double lumen venous cannula and electric perfuser. Four series of patients were thus distinguished depending on their use or not of N2O as the only analgesic and of gallamine. We do not agree with the classical assertion that CT. 1341 has a cumulative effect on some EEG results. The technique is quite inocuous and the authors propose a technique using CT. 1341 at a dose of 0.1 ml/kg for induction of anaesthesia with, later, 1 mg/kg of gallamine. Under a mixture of oxygen and nitrous oxide at 60 p. 100, the maintenance dose advised in 6.17 microliters per kilo, per minute of CT. 1341.

Adult↗
PubMedDate not supplied

[Immediate effects and conditions of effectiveness of a session of mechanical assisted ventilation (M.A.V.) in severe respiratory insufficiency (PaCO2 greater than 50 mmHg) out of intensive care conditions (author's transl)].

Effectiveness and haemodynamic tolerance of M.A.V. in conscious patients with a severe respiratory insufficiency is mainly due to the proper adaptation to ventilator with low frequency and adequate V.T. Thus M.A.V. is an eventual complement to directed ventilation exercises which in addition reduce the "rebound" of hypoxia and hypercapnia after a M.A.V. session. A proper adaptation ensures haemodynamic tolerance. Expiratory time should be sufficient in such obstructive patients. A post inspiratory pause can improve V.C.O2. Nevertheless, it should not shorten inspiratory time to less than one second and for each patient the best ventilatory profile should be properly established taking into account blood gases, circulatory, expired CO2 and clinical monitoring.

Carbon Dioxide↗
PubMedDate not supplied

[Long-term results of intermittent ventilatory assistance for 74 severe obstructive chronic respiratory insufficient patients (PaCO2 greater than 50 Torr) ventilated for more than a year (author's transl)].

From 1967 to 1978, home assisted ventilation (HAD) was applied to 74 severe chronic respiratory insufficient patients (67 COPD-7 restrictive). These patients used volume generators through mouth piece, except 3 of them who had a tracheostomy. The main results of this study are a highly statistically significant decrement (P less than 0,001) of the hospitalization durations and of the frequency of ARF, as well as an improvement of the survival duration in front of a non-tested group, and a significant decrease of haematocrit (less than 0,05) and P.V.R. (P less than 0,01). But blood gases and functional tests are not statistically different. Age (greater than 55 years) and delay after first ARF (greater than 2 years) when starting HAD are considered as pejorative factors.

Blood Gas Analysis↗