Different periods of fasting have no effect on oral glucose tolerance.
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Biomedical subjects
Publications and source records attributed to J F Fielding.
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Perforation of the large bowel can occur as a complication of sigmoidoscopy, rectal or sigmoid biopsy, and even of a simple cleansing enema. If the perforation is extraperitoneal there may be no early symptoms and consequently there may be delay in diagnosis. The risk of perforation during these procedures is small but it should not be ignored. The performance of a barium enema shortly after a rectal or sigmoid biopsy may slightly increase the risk by converting a partial perforation into a complete one. Precautions can be taken to minimize the hazard.
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One hundred and ten patients presented with Crohn's disease confined to the terminal ileum, and indications for their surgical treatment are reviewed. Treatment was either by ileo-transverse side-to-side bypass (21 patients) or primary excision and end-to-end ileo-colic anastomosis (89 patients). In a long follow up (mean 13.8 years) the date and indications for the second major operative intervention are recorded. The cumulative risk of recurrence recorded each year after the primary operation shows that after bypass compared with excision there is approximately twice the risk of requiring a further major operation. After bypass the indication for the second operation is usually a local complication of the still active disease and after excision it is usually a juxta-anastomotic recurrence with stenosis.
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