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Biomedical subjects

J Erben

Publications and source records attributed to J Erben.

At least 109 records · Page 6Linked to original sources
PubMed1978

[Goodpasture's syndrome].

1. The paper summarizes the clinical course, histopathological examinations and immunohistological examinations of 4 personal cases [2 males aged 20 and 26 years, 2 females aged 65 and 18 years] of Goodpasture's pulmorenal syndrome. 2. The characteristic histopathological findings included pulmonary haemorrhage with a focal acute alveolitis and renal lesions that were classed as acute or subacute glomerulonephritis with the finding of scarce multinucleated cells. Such cells are regarded as being of diagnostic value and they are thought to indicate interaction of antibodies with the basement membranes. 3. Immunohistologically, all the cases showed a linear fluorescence following the basement membrane of the interalveolar septa. In 3 of the cases there was linear fluorescence in the glomerular capillary walls. In one case [observation No. 2] who had been hypertensive before death and had had necrotizing arteriitis at postmortem, there was fluorescence of granular type in the kidney believed to indicate the participation of immune complexes in the development of the pathological condition.

Adolescent↗
PubMed1977

[Dialysis technic for regulation of the internal milieu in acute poisoning].

In 72 patients with acute poisoning (15 patients without unconsciousness with 80% of acute renal and hepatic failure, and 57 patients with unconciousness with 10.5% of acute renal and hepatic failure) the significance of the continuous prolonged haemodialysis lasting on an average 12 hours, respectively 18 hours, with the maximum of 33 and 82 hour, respectively. The duration of the haemodialysis was in close correlation with the pH-value of the blood and the duration of the unconciousness. One half of the unconscious patients suffered from dehydration (of them up to 40.3%), which was valuated by the height of the central venous blood pressure. It was also referred to the necessity of the correction of the potassiaemia and glycaemia.

Acute Disease↗
PubMed1977

[IgA nephropathy].

A series of 150 samples of renal tissue obtained by needle biopsy from patients with haematuria were examined immunohistologically. In 15 cases mesangial deposits of IgA were demonstrated. In most cases they were young patients in whom no hypertension, oedema or laboratory findings indicating renal damage could be detected one year later during a follow-up examination. Electron microscopical examination was carried out in the renal tissue of 7 such cases, and showed dense mesangial deposits and a marked subendothelial rarefaction within the basement membrane. The light microscopical findings were variable. Three cases showed minimal lesions, 5 mesangial proliferative glomerulonephritis and 7 mesangial proliferative glomerulonephritis with focal segmental sclerotic alterations within the glomeruli.

Adolescent↗
PubMed1977

[Importance of residual diuresis in patients with chronic pyelonephritis under constant dialysis treatment].

In 55% of 100 patients (54 with glomerulonephritis and 46 with pyelonephritis) who had been dialysed in the permanent dialysis treatment for more than one year the tactics of a dialysis per week was estabished at the beginining of the permanent dialysis treatment: in the diuresis of more than 1 litre a day with the residual glomerular filtration about 5 ml/min, in stabilised body-weight, in controllable hypertension and in the compensated clinical picture of renal insufficiency. The residual glomerular filtration can be presumed only in the optimally hydrated patients. The canulation of the subclavian vein has proved significant for the evaluation of optimum hydration.

Chronic Disease↗