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Biomedical subjects

J Erben

Publications and source records attributed to J Erben.

At least 91 records · Page 5Linked to original sources
PubMed1980

[Investigation of magnesium and calcium in ischemic changes in the human myocardium].

The results are presented of tests for magnesium and calcium and their ratio in the human myocardium affected by ischemia in correlation with macroreaction to dehydrogenases. The cases were examined in the shortest possible time after death, observing strict criteria. Even some of the relatively early postmortem changes were found to block the practical diagnostic uses of the changes of magnestium and calcium metabolism in postmortem material.

Calcium↗
PubMed1979

Serum and ultradiafiltrate middle molecules in hemodialysed patients.

The gel filtration technique was used for the fractionation of middle molecular substances (MMS) in plasma from conservatively treated patients, from dialysed patients with renal failure and in the ultradiafiltrate from dialysed ones. The following observations were made: 1. MMS accumulate in the plasma of conservatively treated patients in chronic renal failure. 2. The accumulation of MMS in dialysed patients is even higher. 3. The elimination of the most important MMS in the ultradiafiltrate is excellent. 4. It is concluded that hemofiltration and ultradiafiltration are indicated also for the removal of MMS, namely in the case of clinical complications which cause a further accumulation of MMS.

Humans↗
PubMed1979

Long-term experience with the technique of subclavian and femoral vein cannulation in hemodialysis.

Large vein cannulation for hemodialysis was used in 1164 patients undergoing dialysis treatment and in an acute dialysis program. Subclavian vein cannulation was utilized in 2494 dialyses, and femoral vein cannulation was used in 2368 dialyses. No significant differences with regard to clinical complications were encountered in either type of cannulation. The mortality rate due to subclavian vein cannulation was 0.12%, while that due to femoral vein cannulation was 0.04%. The main risk of subclavian vein cannulation was arterial bleeding, due to trauma to an artery, and pneumothorax, more likely occurring in asthenic patients or in patients with emphysema. Single-needle hemodialysis using subclavian or femoral vein cannulation gave the same results as the arteriovenous Cimino fistula. Intermittent or combined use of both types of large vein cannulation is advantageous in long-term regular dialysis patients that are waiting for a new fistula.

Catheterization↗
PubMed1979

[Tuberculosis in patients deceased of renal insufficiency in a long-term hemodialysis program].

Eight cases of tuberculosis were seen in a series of patients dying of renal insufficiency after having been subjected to a long-term haemodialysis. In 5 cases Mycobacterium tuberculosis was successfully cultivated (4 were typed as human, 1 as bovine). In 5 cases the disease affected mainly the lymph nodes, not the lungs. In 3 of these a prevalence of abscessing specific granulomas with the presence of leucocytes was noted on microscopical examination. The findings have been regarded as possibly related to an impairment of cellular (lymphocytic) immunity, presumably caused by chronic uraemia or long-term haemodialysis.

Adult↗
PubMed1979

Serum levels of IgM, IgD, IgA and IgG before and during rejection of renal allotransplants.

In recipients of renal allotransplants the relationship of IgM, IgA and IgG serum levels to 26 rejections was investigated, as well as the relationship of IgD and 22 rejection. For IgM and IgG a significant decline was found in the whole group (p less than 0.05) and in the sub-group of rejections after a period longer than one month following transplantation (p less than 0.05 in IgM and p less than 0.02 in IgD). As compared with values before rejection, a decline of IgM occurred in 11 rejections which amounted to more than 20% and a decline of IgD in 10 rejections by more than 50%. Changes of the serum levels of IgA and IgG were not statistically significant (p greater than 0.05). In recipients of renal allotransplants serum immunoglobulin (Ig) levels of the main classes were investigated for two reasons: (1) as part of a check-up of the condition of the graft and screening of rejection and (2) to detect possible deficiencies of humoral immunity with increased liability to infections. As regards monitoring of the risk of the rejection crisis, hitherto assembled experience did not provide an unequivocal answer in which class of Ig the greatest change may be expected, whether a rise or fall, and it is not even clear whether investigations of serum Ig levels will be a positive contribution. There is only agreement on the point that IgA levels are not related to rejection; according to some authors this applies also to IgM and IgG (8, 11). Other authors (1, 15, 17) appreciate in conjunction with rejections the importance of high IgM and IgG levels, while other workers observed a significant decline of IgM (13, 16, 19). IgD levels were investigated in our previous work on the relationship of renal functions and serum Ig levels in recipients of renal allotransplants (7); we found no reports on the relationship between IgD and rejection.

Adolescent↗