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Biomedical subjects

J E Mitchell

Publications and source records attributed to J E Mitchell.

At least 163 records · Page 9Linked to original sources
PubMed1982

Antipsychotic drug therapy and sexual dysfunction in men.

The authors review the literature on male sexual dysfunction associated with antipsychotic drug treatment. Erectile and ejaculatory disturbances have been most frequently reported. Changes in libido have also been reported, but the effects of these drugs on sexual drive have apparently not been systematically studied. Fortunately, most types of sexual dysfunction associated with antipsychotic drugs appear to be medically benign and reversible with drug discontinuation. An exception is priapism, which necessitates prompt urological consultation and may require surgical intervention.

Antipsychotic Agents↗
PubMed1982

Thyroidectomy: is Lugol's iodine necessary?

In a randomised controlled clinical trial of Lugol's iodine against placebo in 44 patients undergoing thyroidectomy we have failed to show any benefit in terms of reduced bleeding or operative facility after using iodide solution.

Adult↗
PubMed1982

Cardiac effects of lithium therapy in man: a review.

The literature concerning possible cardiotoxic effects of lithium therapy in man is reviewed. Reports indicate a high frequency of electrocardiographic T wave morphology changes with lithium therapy. Therapeutic and toxic levels of lithium have infrequently been associated with serious cardiac dysfunction. Of particular concern are cases of sinus mode dysfunction or sinoatrial block and the appearance or aggravation of ventricular irritability. The incidence of cardiac complications may increase with age. The necessity or cardiac screening and monitoring of patients receiving lithium is discussed.

Arrhythmias, Cardiac↗
PubMed1982

Autoimmune hemolytic anemia in children.

Autoimmune hemolytic anemia may represent an acute medical emergency. The anemia is normocytic normochromic and is usually associated with an elevated reticulocyte count. The diagnosis is confirmed by positive direct and indirect Coombs tests. Treatment consists of blood transfusion if the anemia is life-threatening. Steroids promote a decrease in the serum immunoglobulin level and block binding of antibody to the red blood cell. Splenectomy is reserved for those patients who fail to respond to steroids.

Anemia, Hemolytic, Autoimmune↗
PubMed1981

Requesting previous psychiatric records. Do they come and are they worth obtaining?

This study examines the response rate to requests for previous records on adult psychiatric outpatients and the usefulness of the records received. Usable records were received in response to only 64.6 per cent of requests. In 40.9 per cent of the records examined, previous records revealed important information which had not been gathered at the time of outpatient evaluation. Possible reasons for the rate of response are discussed. The authors conclude that important information can be missed during the process of evaluation and that previous records may significantly add to the available data base on which to make diagnostic and treatment decisions. However, not infrequently requests for previous records are not answered.

Adult↗
PubMed1981

Bulimia: a report of 34 cases.

A series of 34 patients with Bulimia is presented. The patients were young females who usually experienced the onset of eating problems by early adulthood. Most had binge eating episodes on a daily basis, frequently followed by vomiting. Although the majority had never had active anorexia nervosa, all of these patients demonstrated characteristics often described in anorectic patients including a preoccupation with food and an exaggerated fear of becoming obese. Many appeared to be clinically depressed. The association between stealing behavior, chemical abuse and bulimia suggests problems with impulse control in this population.

Adolescent↗
PubMed1980

The colon influences ileal resection diarrhea.

Fecal mass and electrolyte concentrations from 25 ileectomy and/or colectomy patients on known diets were used to assess those factors most responsible for their diarrhea. In 18 ileectomy patients the severity of diarrhea, expressed as a fecal weight, was a function of both percent of colon and centimeters of ileum removed. Linear regression analysis, however, showed that the extent of missing colon had three times the effect of missing ileum on fecal weight. Patients who lost the ileocecal valve and part of the right colon had more diarrhea than those who lost comparable lengths of ileum but had this area preserved. Fecal ion concentrations seemed independent of diet but were related to fecal weight and the amount of colon and ileum removed. Potassium concentration was strongly dependent on the amount of colon lost, while sodium concentration was more influenced by the length of resected ileum. Choloride was most dependent on fecal weight. As expected, fecal fat correlated strongly with the extent of ileum removed. Regresison equations were constructed from the electrolyte data which described and predicted the extent of lost ileum or colon. Our data were also used to separate patients with less than 100 cm of ileum removed from those with more extensive resections. The severity of diarrhea following ileal resection depends primarily on the amount of contiguous colon removed. Varying loss of ileum and colon produced predictable effects on fecal weight and electrolyte composition. Surgeons should preserve the maximum amount of colon possible to reduce the severity of diarrhea in these patients.

Adult↗
PubMed1975

Undiagnosed bacterial meningitis in Vermont children.

Community-acquired bacterial meningitis in Vermont children under 5 years of age was recognized less frequently in 1967-1970 in those towns with low total hospitalization rates than in towns with hospitalization rates above 15 admissions per 100 population. Using the towns with high hospitalization rates as a norm, it was found that towns with fewer recognized meningitis cases than expected had significantly greater rates of death from obscure causes in children 1-59 months of age in 1967-1970. It is suggested that about 17 deaths in 1967-1970 in Vermont children 1-59 months of age were associated with the failure to recognize bacterial meningitis in children from towns with low rates of medical care utilization.

Bacterial Infections↗