Classification: revising DSM-III and ICD-9.
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Biomedical subjects
Publications and source records attributed to J E Cooper.
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In baboons ABH antigens are found on vascular endothelium but not on red blood cells. This newly observed pattern of distribution is intermediate between that of lower mammals (in which ABH antigens are not found on endothelia or on red cells) and that of humans (in whom ABH antigens are present on both). In both types of cells the expression of these ABH antigens was expected to be under the same H-h genetic control, but the dissociation between the expression of ABH on red cells and on vascular endothelium shows that some other factor must by involved. The ABH antigens of exocrine secretions were expected to be under control of the Se-se system. However, some epithelial structures express ABH antigens in nonsecretor baboons (e.g., striated ducts), some cells express only H without A or B (e.g. biliary ducts and acinar cells of salivary glands), and some cells express only the H antigen at early stages of differentiation and the A or B antigens at later stages of differentiation (e.g. epidermis). ABH antigens were also found in the nervous system, a previously unreported site. All of these observations necessitate a reappraisal of current theory of the genetic control of tissue expression of ABH antigens.
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A proliferative lesion in a Hermann's tortoise (Testudo hermanni) was identified as a neurilemmal sarcoma: it was successfully treated by excision and cryosurgery.
Experimental infections of canaries with an avian trypanosome, Trypanosoma bouffardi, isolated from West Africa demonstrated that these infections can cause pathological changes in tissues. Enlargement of the spleen coincided with peak parasitaemia but no other gross changes were observed. Histopathological examination of infected and control birds revealed focal myocarditis and lymphoid hyperplasia, in infected birds, which are consistent with trypanosome infection. Avian trypanosome infections are not usually regarded as pathogenic but our results suggest that pathological changes occur which are similar to those observed in mammals infected with salivarian trypanosomes.
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The Hunterian Museum contains 14 specimens from birds of prey. Four of these are in the Pathological Series and comprise 3 healed fractures and 1 skeletal lesion of doubtful aetiology. Hunter made useful, if limited, contributions to this branch of avian pathology and his role is evaluated.
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There are legal implications in deciding when a sick or injured bird or prey is able to be released. Important considerations are the health of the bird, its relationship with man and the locality in which it is to be released. Recommendations are made in order to help veterinary surgeons tackle this problem. Criteria for assessing health are outlined and discussed.