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Biomedical subjects

J Dry

Publications and source records attributed to J Dry.

At least 109 records · Page 6Linked to original sources
PubMed1983

[Human basophil degranulation test and double diffusion in pulmonary hydatidosis].

A slide human basophil degranulation test (HBDT) and a double-diffusion test were done in 37 patients with suspected pulmonary hydatid disease. Among the 31 patients in whom a diagnosis was firmly established, 22 had a pulmonary hydatid cyst and 9 did not (controls). The HBDT was at least 35% in 17 of the 22 patients with hydatid disease; 16 of these exhibited a precipitation arc. Among the 9 controls, none had a HBDT above 30% and three had a precipitation arc. In this localization of hydatid disease, compared to the double-diffusion technique, the HBDT has similar sensitivity (0.77 versus 0.73 but higher specificity (1 versus 0.67).

Basophils↗
PubMed1983

Total IgE, specific IgE and prick-tests against foods in common migraine--a prospective study.

A prospective study of total IgE, specific IgE against 12 common foods, and prick-tests with 11 common food allergens was performed on 50 consecutive migraine sufferers. Total IgE levels were found above 100 kU/l for seven patients, but five of them were atopic. Prick-tests and RAST were positive for four and six patients (class 1), respectively. Food challenge on these six patients did not cause any migraine attacks. This study thus indicates a very low frequency of allergic dietary migraine to common foods.

Adolescent↗
PubMed1982

[Hypereosinophilia in cancer and cirrhosis : utility of total eosinophil count (author's transl)].

A total eosinophil count (TEC) and a white blood cell count (WBCC) were performed simultaneously in 213 patients. Discrepancies were found between TEC and WBCC. WBCC did not allow detection of hypereosinophilia (TEC exceeding 300 eosinophils/microliter) in 45 patients. Patients were classified in three groups : controls (n = 27), benign disease (n = 65), and apparently cured cancer (n = 36). There was no significant difference between total eosinophil counts for these three groups (Wilcoxon non-parametric test). The incidence of hypereosinophilia (TEC exceeding 300) was similar in the three groups (11%, 14% and 6%). Average TEC levels were determined in 20 patients with decompensated hepatic cirrhosis, in 31 patients with active cancer, and in 14 patients with infection. These levels were significantly different from those found in each of the three previous groups. (Wilcoxon test). The incidence of hypereosinophilia (greater than 300/microliter) was significantly higher among patients with cirrhosis (50%) or active cancer (58%). The possible mechanisms of this hypereosinophilia and it's eventual prognostic utility are considered.

Adolescent↗
PubMed1982

Platelet serotonin uptake and migraine.

Platelet serotonin uptake characteristics (Km, Vmax, y) were determined in platelet-rich plasma for 11 common migraineurs and 15 health volunteers. All three parameters were decreased only for the three patients having a migraine attack during blood collection, Migrainous platelets isolated on dextran or resuspended in control plasma exhibited normal serotonin uptake. This finding suggests that plasmatic factor(s) may be responsible for the decrease of platelet serotonin uptake observed during migraine attacks.

Blood Platelets↗
PubMed1982

[Refsum's disease: 10 years of a diet low in phytanic acid and phytol].

The authors report the evolution of two cases of Refsum's disease, treated with a specific phytol and phytanic acid diet for ten years. This treatment is effective leading to a rapid and stable fall of phytanemia, and a progressive improvement of the peripheral neuropathy and cerebellous symptoms, then prevent from quite new aggravation. Any symptom in favour of a cardiac, pulmonary or renal disease was observed during the past ten years. On the other hand, the sight and hearing disorders remained unchanged and are responsible to a major discomfort in this long-dated evolution. The strict liquid diet is quickly abandoned on account of a bad tolerance (diarrhea), but the ordinary diet is better endured, and is sufficient to keep a low phytanemia; this need a permanent continuation.

Adult↗
PubMed1982

[Pharmacokinetics of theophylline and circadian rhythm].

In the purpose to evaluate the circadian changes of theophylline pharmacokinetic, 8 healthy subjects (age range 22-39 y, weight 54-91 kg) were given a single oral dose of 4,5 mg/kg theophylline solution. Administration was made randomly at 9 a.m. after 12 hours fasting and at 9 p.m. After evening administration the subjects remained awake during the night and a standardized meal was served 4 h and 9 h after theophylline intake. Plasma theophylline concentrations were measured by a high performance liquid chromatography. Absorption is significantly faster in the morning than in the evening but C max values were identical. Plasma elimination half-life is significantly different (8,01 +/- 1,95 h in the morning, 6,23 +/- 1,75 h in the evening). No significant modifications were observed of the area under the curve, the body clearance, the apparent volume of distribution. There were no differences in the total body clearance, the area under the concentration-time curve, the apparent volume of distribution.

Adult↗
PubMed1982

[Acquired B antigen: a new case].

A 86 year old woman, in good health but "Escherichia coli" urinary infection, was found to have an abnormality in blood group determination. 3 years ago, blood group of this patient was group A and now, precise determination shows the existence of an acquired B antigen. Disappearance of this acquired B Ag was obtained in 3 months after the urinary infection's treatment. The most cases of acquired B Ag result from neoplasic diseases or infection with enterobacteriacea. Physiopathology of acquired B Ag is secondary to the action of a deacetylase enzyme produced by enterobacteriacea, on group A1 erythrocytes.

ABO Blood-Group System↗
PubMed1982

[Pain sensitivity in obese individuals].

Using the measure of the nociceptive threshold by saphenobicipital reflex method in 30 obese women (30 p. cent or more above ideal weight) and 20 controls, the authors observe that in the obese group the threshold of the nociceptive flexion reflex is significantly lower than in controls (6.57 +/- 3.52 mA in obese; 9.42 +/- 1.90 mA in controls). There is a significant reverse correlation between degree of overweight and the threshold of the nociceptive reflex. The authors suggest the hypothesis of an abnormality of the endogenous morphine-like system or of its control in human obesity.

Adult↗