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J Doucet

Publications and source records attributed to J Doucet.

At least 109 records · Page 6Linked to original sources
PubMed1989

[An aid to the electrophysiological diagnosis of diabetic peripheral neuropathy].

The electrophysiological diagnosis of peripheral neuropathy in diabetics becomes increasingly difficult with the increase in number of parameters measured. We have examined 102 subjects: 60 diabetics, 32 control subjects and 10 with impaired glucose tolerance. From the 37 recorded parameters during 8 examinations, a linear discriminant analysis allowed us to separate the 19 diabetics with clinical neuropathy and the control subjects with only 5 parameters, with a good concordance (96%): the motor conduction velocities (MCV) of the peroneal and median nerves, the amplitude of the action potential (AP) of the sural nerve, the Hmax/Mmax ratio and the M latency of the Hoffman reflex. These parameters, weighted with a coefficient, constitute a score of discrimination. This score has been tested by the Jackknife method on the same sample (94% of well-classified patients), then validated on the other patients. Thus we propose a method to aid the diagnosis of diabetic peripheral neuropathy, without the arbitrary character of the classical single parameter method, and allowing easy repetition.

Adult↗
PubMed1989

Carbimazole-induced acute cholestatic hepatitis.

A case of carbimazole-induced cholestatic hepatitis is presented. A woman received carbimazole for hyperthyroidism for 3 months. Five months later, she had prompt recurrence of cholestasis parameters after rechallenge (2 days of treatment). Histologic examination showed predominantly centrilobular cholestasis. Only 5 other cases have been published in the literature. An idiosyncratic mechanism seems likely.

Acute Disease↗
PubMed1989

[Congenital ventricular septal defect with late detection. Apropos of a case in an adult].

The authors report the case of a congenital interventricular communication discovered in a 75 year-old female patient. The shunt was identified on the cardiac Doppler and confirmed by catheterization. It was a type IIa interventricular communication which decompensated in the course of a pulmonary embolism. This case points out how rare is the diagnosis of congenital interventricular communication made during adulthood, and emphasizes the advantage of the Doppler in the diagnosis of ventricular shunts.

Age Factors↗
PubMed1988

[Not Available].

Explore the source record for details and available documents.

Botany↗
PubMed1986

Localized fibrous tumour of serosal surfaces. Immunohistochemical and ultrastructural evidence for a type of mesothelioma.

It is uncertain whether localized lesions of serosal membranes have a kinship to mesotheliomas or are truly fibromatous in nature. Ultrastructural and immunohistochemical investigations were carried out on 12 localized benign and malignant pleural and peritoneal tumours from 10 patients. Electron microscopic findings, including the consistent and non-fibroblastic cellular organization of localized neoplasms, the presence of some form of intercellular junctions in 7 of 10 cases, basal lamina deposition in 3 cases, and polarized microvilli in one case indicated a form of mesothelial differentiation. Using monoclonal and polyclonal antibodies, positive immunostaining of tumour cells for cytokeratin peptides was detected in one case, while antibody to vimentin stained four cases. Light microscopic, ultrastructural and immunohistochemical features of one benign localized serosal tumour, with a unique blend of epithelial and spindle cells, provided further evidence for a histogenic link between localized serosal tumours and diffuse epithelial mesotheliomas. On the basis of the current findings and reports in the literature, it would appear that the majority of localized tumours of serosal membranes are a subset of mesothelioma, while a minority are fibromas.

Adult↗
PubMed1983

[Education of a hospitalized diabetic population].

During the second semester of 1981, all the diabetic patients who were hospitalized in the department (142 IDD and 75 NIDD) followed an educational program. Approximately half the patients were unable to follow the entire course, owing to visual, motor, intellectual or linguistic impairment. Few patients refused the course (8 cases). Evaluation of the theoretical knowledge at discharge showed poor results in 47% of IDD and 64% of NIDD, with patients in the latter group appearing to be less motivated. Advanced age, unemployment and alcoholism are detrimental factors. In contrast, among 71 IDD who followed only part of the course because of a handicap, 25 nevertheless acquired satisfactory knowledge, justifying an educational program with limited objectives. At follow-up at the outpatient clinic, insulin dependent patients exhibited better metabolic control, self-monitoring and acceptance of their disease; however, the patients who are seen at follow-up examinations are those who have the best theoretical knowledge. A comparative study of hospitalizations shows that admissions for hypoglycemia have decreased between 1978 and 1981, but education is not the only factor. The shortcomings and possible improvements are discussed.

Diabetes Mellitus↗
PubMed1983

Estimation of human susceptibility to the high-pressure nervous syndrome.

Twenty-four professional divers were put through a series of electroencephalographic (EEG) and psychometric tests at the surface and at 180 m after a fast compression (15 min) in an attempt to determine their susceptibility to high-pressure nervous syndrome (HPNS). The subjects were classified according to the EEG changes between the surface and 180 m: group 0, less than 10% increase in theta-band activity in the anterior region of the scalp; group 1, between 10 and 100% increase in theta-activity; group 2, theta-activity increase above 100%. Eight subjects were selected to make a dive to 450 m to verify the quality of our classification (3 from group 0, 3 from group 1, 2 from group 2). The results showed that, for the psychometric tests, the large individual variability between the surface and 180 m does not allow us to prejudge the behavior of each subject at 450 m, but the classification established from absolute values is stable from the surface to 450 m. For the EEG activities, intensity of the modifications at 450 m can be predicted at group level by a 180-m dive, performed with fast compression and similar breathing mixtures.

Disease Susceptibility↗