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Biomedical subjects

J Craig

Publications and source records attributed to J Craig.

At least 127 records · Page 7Linked to original sources

Teaching modules.

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Adaptation, Psychological↗

A survey of anaesthetic misadventures.

Reports of anaesthetic misadventures were regularly collected in the Anaesthetic Department of a district general hospital, to identify recurring problems. Eighty-one misadventures, none of which had serious outcome, were reported during a 6-month period, in which 8312 anaesthetics were administered. Human error was more frequently responsible than equipment failure, and failure to perform a normal check was the factor most frequently associated. Local hazard warnings were circulated when necessary to members of the Department, and the reports formed the basis of departmental discussion and teaching.

Accidents↗

A monoclonal antibody detecting the Ly-9.2 (Lgp 100) cell-membrane alloantigen.

A mouse monoclonal cell line (20-1.5) was produced by the cell fusion method and the antibody secreted by this line defined the Ly-9.2 specificity--the reciprocal specificity to that previously identified as the Lgp 100 or the T100 molecule. Although most concentrated on lymph-node cells, the antigen is also found on thymocytes, spleen and bone-marrow cells as well as liver and brain tissue. The monoclonal antibody precipitates a 100,000 molecular moiety from thymocytes. The antigenic specificities appear to be highly immunogeneic and antibodies to these specificities contaminate many antisera. These sera are noncytotoxic as is the case with the monoclonal antibody even though it is of the IgG2a subclass. As with T100 or Lgp 100, the Ly-9 locus appears to be linked to the H-25 locus.

Animals↗

The contribution of specialists to the delivery of primary care.

Despite increased numbers of medical-school graduates and opportunities for "primary-care" specialty training since the mid-1960's, many believe that the shortage of physicians delivering generalist care will continue through the 1980's. Missing, however, is solid information on the role of physician specialists in providing such care. Two national studies have shown that one of every five Americans now receives continuing general medical care from a specialist physician. Our study suggests that, despite the current shortage of generalist-physician services, continuing specialist participation in primary care will lead to sufficient generalist medical services by the mid-1980's. Whether specialist participation is the most appropriate or cost-effective way to improve access to such care is unclear. However, until this question is resolved, more governmental regulation of graduate medical education may be unwise. Offering all physicains, regardless of specialty, more primary-care experience during residency training might better deal with this aspect of American medical practice.

California↗

SI for you and me.

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Blood Pressure↗

Microdetermination of naphthionic acid in serum and amniotic fluid.

A simple, rapid, sensitive, and reproducible microdetermination of naphthionic acid (NA) in serum and amniotic fluid is described. The detection limit of the method is 1 ng NA in 20 microL serum, and 3 ng NA in 50 microL amniotic fluid. The concentration of nonderivatized NA was measured by fluorescence spectrophotometry (excitation 328 nm, emission 420 nm) of the supernate, after precipitation of proteins with absolute ethanol and heating for 30 min at 75 degrees C. Standard deviations of determinations for 2, 10, and 50 ng NA in 20 microL serum were 10.1, 7.59, and 7.64%, respectively. An analyst can perform about 100 determinations daily; results are available within 2 hr of sampling. A modification of the procedure to permit quantitation of NA in urine is also described.

Amniotic Fluid↗

The urban fiscal crisis in the United States, national health insurance, and municipal hospitals.

The fiscal stress which many U.S. cities are currently experiencing, the persistent problems of large-city local government hospitals, the recent decisions for selected public hospital closings in New York City and Philadelphia, and the prospective enactment of a program of national health insurance collectively raise questions about the viability of the nation's major municipal hospitals. While the majority of the nation's 40 largest cities are in a state of economic and demographic decline, the diversity which characterizes their fiscal conditions and their responses to fiscal stress suggests caution in generalizing from the highly publicized New York City experience in asserting the ability of cities to continue to maintain public hospital activities. Indeed, there is considerable evidence to indicate that the staying power of municipal hospitals is quite substantial even in circumstances of severe fiscal stress. Further, analysis of the effect of Medicaid implementation on municipal hospital utilization and of the impact of prospective national health insurance programs on the demand for and supply of medical services suggests that municipal hospitals will continue to be important providers of health care services for many years to come.

Health Expenditures↗

Anecdotal records.

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Employee Performance Appraisal↗

Collision behavior of young drivers. Impact of the change in the age of majority.

A comparison of the number of collisions experienced by young male drivers in London, Ontario, before and after the reduction in the legal age for drinking and purchasing alcoholic beverages from 21 to 18, indicated that the change in the law led to an increase in the collision involvement of young drivers.

Accidents, Traffic↗