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Biomedical subjects

J Cooper

Publications and source records attributed to J Cooper.

At least 505 records · Page 28Linked to original sources
PubMed1980

The role of periurethral colonization in the aetiology of recurrent urinary infection in women.

Periurethral bacterial colonization was studied in two groups of women by taking samples with a polystyrene sponge. Just over half (56 per cent) of 81 sexually-active women attending a family planning clinic were not colonized in the periurethral area; subjects who were colonized usually showed large numbers of a single bacterial species. On the other hand, all 38 patients who were attending a clinic because of recurrent urinary infections were colonized in the periurethral area; most of these yielded a heavy growth, and more than one bacterial species was usually isolated. Gram-positive cocci predominated as the colonizing flora in both groups, a finding which is in marked contrast to the predominant aetiological agents in urinary infections, namely Gram-negative bacilli. We therefore conclude that colonization of the periurethral area is not the decisive event in the initiation of a urinary infection.

Adolescent↗
PubMed1980

Rapid assessment of stereopsis in pre-verbal children using operant techniques: a preliminary study.

A new operant conditioning program, based upon principles of errorless discrimination learning, was used to assess stereopsis in 24-35 months old children. Results indicated that this program was more successful in generating responding to stereograms than standard contour or random dot tests of stereopsis. It was concluded that the most effective procedure for evaluating subjective visual findings in pre-verbal patients is one that recognizes the importance of programmed discrimination learning and operant motivational techniques.

Age Factors↗
PubMed1979

Panoramic viewing, visual acuity of the deviating eye, and anomalous retinal correspondence in the intermittent exotrope of the divergence excess type.

Monocular visual acuities in a binocular field of view, field of view under binocular conditions, and retinal correspondence were investigated in five intermittent exotropes of the divergence excess type. Results indicated that all five intermittent exotropes demonstrated (1) normal visual acuity in the deviating eye without suppressing the fixating eye, (2) a lateral extension of the temporal field of view (panoramic viewing), (3) anomalous retinal correspondence.

Adolescent↗
PubMed1979

Effect of dicarboxylic acids on normal human melanocytes in dispersed tissue culture.

Since dicarboxylic acids are competitive inhibitors of tyrosinase, and effective in treatment of hyperpigmentary disorders, such as chloasma and lentigo maligna, probably due to a cytotoxic effect on abnormal melanocytes, it is of interest to examine their effect on normal melanocytes in tissue culture. Azelaic or dodecandioic acids were added (150-200 micrograms/ml) to dispersed cultures of epidermal cells, and melanocytes were examined by electron microscopy after 7, 10, 15, 20 and 30 days. Apart from a stimulation of melanogenesis, the presence of dicarboxylic acids in the culture medium caused no detectable damage to melanocytes, nor did they prevent growth of a second generation of cells.

Culture Techniques↗
PubMed1979

A double-blind trial of single-dose chemoprophylaxis with co-trimoxazole during vaginal hysterectomy and repair.

Twenty-five patients received 10 ml co-trimoxazole (800 mg sulphamethoxazole and 160 mg trimethoprim) and 25 a placebo by intravenous infusion during one hour from the commencement of surgery for vaginal hysterectomy with anterior colporrhaphy and posterior colpo-perineorrhaphy. Single-dose chemoprophylaxis with co-trimoxazole was shown to be effective in reducing the incidence of postoperative febrile morbidity and urinary tract infection, especially that caused by Proteus species.

Aged↗
PubMed1979

C- and G-banding patterns and chromosomal morphology of some breeds of Australian cattle.

A cytogenetical study using metaphase chromosomes from cultured lymphocytes, was made of 2 Banteng (Bibos banteng) steers and 218 bulls representing 13 purebreeds (Bos taurus type, Bos indicus type and Sanga) and 7 cross-breeds. Studies were made of photographic karyotypes of Giemsa stained and C-banded chromosomes of bulls of each breed and of B-banded chromosomes from 3 breeds of Bos indicus and one cross-breed Australian Friesian Sahiwal) cattle. The relative lengths of chromosomes of Bos taurus and Bos indicus bulls were compared and significant difference in relative lengths of the X chromosomes were noted between these two species. There was a differences in morphology of the Y chromosomes; Sanga, Banteng and Bos taurus type breeds had a small submetacentric Y chromosome, except for the Jersey which had a metacentric Y chromosome. All Bos indicus type bulls had an acrocentric Y chromosome but the Droughtmaster breed had two forms of the Y chromosome (submetacentric and acrocentric). The C-banding patterns of the autosomes and X chromosomes were similar for all breeds while those of the Y chromosomes of Bos indicus type cattle allowed their accurate identification. G-banding patterns of Bos indicus resembled those of Bos taurus and enabled pairing of homologous chromosomes. Centromeres of the autosomes were unstained but those of the sex chromosomes were darkly stained.

Animals↗
PubMed1979

Clinical stereopsis testing: contour and random dot stereograms.

Stereopsis testing has received renewed interest because of its relationship to strabismus and amblyopia. This paper discusses clinical implications of stereo responses on traditional line stereograms and on newly developed random dot stereograms in normals, strabismics and amblyopes. Random dot stereograms are computer generated which when binocularly fused give rise to stereoscopic depth.

Age Factors↗
PubMed1979

Advanced diagnostic procedures for evaluating the visual status of the child.

Single cell studies of cats and monkeys, recent behavioral testing methods, and improved sophisticated electrodiagnostic procedures have resulted in a new awareness of and concern for the development of the visual system. This paper will review select relevant research and highlight some of the new diagnostic vision tests presently available for the clinical assessment of infants and young children.

Amblyopia↗
PubMed1979

Assessing the Frisby Stereo Test under monocular viewing conditions.

A new random dot stereoscopic test, the Frisby Stereo Test, was evaluated to determine whether monocular information may be used in making correct responses. The performance of 34 optometry students was assessed under both monocular and binocular viewing conditions. Results indicated that one student was able to pass the test upon the initial monocular presentation. Two additional students were able to pass the test monocularly following binocular exposure. It was concluded that the Frisby Stereo test is about as effective as any other commercially available RDS test when used with adults. However, it may have potential deficiencies when used with children.

Adult↗
PubMed1979

Comparing stereoscopic performance of children using the Titmus, TNO, and Randot stereo tests.

The stereo acuities of 112 children between 3 and 11 years of age were assessed using the Titmus, TNO, and Randot stereo acuity tests. Results indicated that stereo acuity test scores improved with age and that performance variability decreased with age. Normal adult findings were achieved by age 7. Generally the Randot Stereo test yielded the best stereo acuity performances. It was concluded that the Randot stereo test is a better clinical test for use with children than either the Titmus or TNO stereo tests.

Age Factors↗