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Biomedical subjects

J Civatte

Publications and source records attributed to J Civatte.

At least 163 records · Page 9Linked to original sources

[MacCune-Albright syndrome. Apropos of a case].

The MacCune-Albright's syndrome as described by these authors in 1936 and 1937 is extremely rare if one considers the complete form consisting in the triad: café-au-lait spots, fibro-osseous dysplasia, endocrine disturbances. We report an additional case in a 5 year old girl with an precocious puberty. Within a 10 year follow up occurred a polyostotic fibrous dysplasia with pathologic bone fractures in cystic areas, and a right exophthalmos induced by a cyst of the large wing of the sphenoid bone. All these lesions led to orthopaedic and neural surgical procedures. The early puberty of central origin (as proved by the LH-RH test) was treated during 7 years by medroxyprogesterone acetate with an excellent result. No peripheral endocrine syndrome was evidenced. This case stresses the multiple problems arising in the disease and the necessity of a long lasting careful follow up.

Child, Preschool↗

[Lichen planus with linear IgG and C3 deposits at the dermal-epidermal junction (author's transl)].

Report of 4 cases of clinically and histologically typical lichen planus with a linear IgG and C3 deposit at the dermal-epidermal junction in involved (4/4) and healthy (2/2) skin, as detected by direct immunofluorescence. Indirect immunofluorescence was negative (3/3). In these 4 cases, the clinical aspect was different: there were no vesiculo-bullous lesions in case 1; case 2 and 3 were of the partly vesicular type with dermal-epidermal separation only in the involved skin; in case 4, bullae were present on both healthy and lesional skin. This suggests that there might exist a broad spectrum ranging from lichen planus without clinical vesiculo-bullous lesions, but with linear IgG and C3 deposits, to lichen planus associated with clinical, histological and immunological symptoms of bullous pemphigoid.

Adult↗

[Mascaró's eccrine syringofibroadenoma. Discussion of a case].

The authors report a case of eccrine syringofibroadenoma. The only difference with the original cases as described by Mascaró in 1963 is that it contains only a few glandular structures. The histologic pattern is also similar to that of the acrosyringeal naevus recently described by Weedon and Lewis, so that it seems needless using a new terminology: these tumors can be considered as examples of eccrine sytingofibroadenoma.

Biopsy↗

[Disseminated actinomycosis presenting with multiple subcutaneous abscesses (author's transl)].

The case report describes a patient hospitalized for multiple subcutaneous abscesses who presented a four-year history of recurrent skin lesions and a fifteen-year history of non specific bronchopulmonary infections requiring segmental resection. The diagnosis of actinomycosis, A. israeli species, was established by culture of surgical drainage material from a thoraco-abdominal wall abscess. Muscle and bone involvement of the right thigh was subsequently demonstrated. There was no evidence of pulmonary infection at the time of hospitalization. Treatment with Penicillin G was curative. A review of the literature is presented together with a summary of thirteen reported cases. Although disseminated actinomycosis has become very rare since the introduction of antibiotic therapy, patients share similar features and a common clinical pattern which are highly evocative of the disease. All patients described had preceding pleuropulmonary disease, characteristically chronic. Evolution of cutaneous lesions was subacute or chronic. In all cases, there was significant delay (months to years) between the initial appearance of skin lesions and subsequent diagnosis. In most cases, actinomycosis had not been suspected. Diagnosis was usually established by isolation and identification of the micro-organism in cultures of purulent material obtained from cutaneous lesions. Despite the probability of hematogenous disease dissemination, pleuro-pulmonary foci were only rarely demonstrated. Prolonged antibiotic therapy was curative in all treated cases.

Abscess↗

[Clinical diagnosis of basal cell epitheliomas of the face (author's transl)].

Basal cell epitheliomas occur most frequently on the face and have very variable appearances: cicatricial and flat, ulcerous, even deep, and nodular, sclerodermiform, or pigmented. A very positive diagnostic finding is small epitheliomatous pearls often grouped together at the periphery of the lesion. Though the effects of these lesions are purely local, as metastases never occur, they frequently have a tendency to relapse.

Basal Cell Carcinoma↗

[Reappearance of soft chancre: comments on the current epidemic in Paris (author's transl)].

A total of 678 cases of soft chancre were treated in one hospital between 1973 and 1979. The majority of the patients were males (97 p. cent), and most of them came originally from Maghreb or Black Africa. Contamination was from prostitution (61 p. cent) or chance acquaintances (29 p. cent). The genital ulceration was often clinically atypical, frequently syphiloid; pain was present in only 59 p. cent of cases, and adenopathy, noted in 63 p. cent of patients, had the appearance of an inflammatory bubo in only 23 p. cent. The present high frequency of soft chancres, and their misleading clinical characteristics, makes it sometimes difficult to establish the clinical differential diagnosis from syphilitic chancre, but confirmation of the latter is supplied by direct examination and culture to search for Ducreys bacillus, this being indispensable for establishing the correct diagnosis. Treatment with sulfamethoxazole trimethopin or streptomycin prevents complications and cures the affection in one or two weeks.

Adolescent↗

[Juvenile spring eruption (author's transl)].

Juvenile spring eruption is seen in early spring and needs a combination of different factors such as light exposure and chilling. It affects mainly boys aged 5-15 or young male adults. It involves the ears in most of the cases and may itch. The helix develops reddish papules, many of which becoming vesicular and later on crusty. Sometimes papular lesions appear on the back of the hands. The lesions heal within 2 weeks without scarring. Recurrences during following springs can be seen. Juvenile spring eruption cannot be reproduced. Histopathology study performed on 2 cases reveals a picture close to erythema mulutiforme and confirms Burckhardt's findings.

Adult↗

[Cowden's disease : multiple hamartomata syndrome (author's transl)].

The third case of Cowden's disease to be discovered in France is reported. The authors emphasize the means for the diagnosis of multiple hamartomata, the typical symptoms and signs in the case reported, and that the family history included a daughter aged 8 years with macrocephaly, and slight mental retardation, who had already been operated upon twice for tonsillectomy.

Facial Neoplasms↗

[Kaposi's disease (author's transl)].

A case of Kaposi's disease is reported with a lesion in the buccal mucosa, and the history, classification, signs and symptoms, and treatment of this disease are described.

Aged↗