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Biomedical subjects

J Civatte

Publications and source records attributed to J Civatte.

At least 145 records · Page 8Linked to original sources
PubMed1983

[False forms of Bowen disease of the genital mucosa].

This review deals with the lesions of the genitalia histologically mimicking Bowen's disease, yet behaving like a benign process. The report is based on data from the literature and on 14 personal cases, four of which are described here as examples. Some of the cases, mostly young patients, showed spontaneous regression; in others condylomata acuminata developed on the site of the lesions; in rare instances a "transformation" in lichen planus occurred. For these not really precancerous conditions the at present most widely accepted name is bowenoid papulosis. As far as etiology is concerned, the responsibility of human papilloma virus is generally accepted or considered likely, although there are only very few cases when the virus has really been evidenced. Diagnosis of a pseudo-Bowen's disease can only be made after clinico-pathologic correlation. A careful follow-up is necessary if it has been decided not to destroy the lesion.

Adult↗
PubMed1982

[An epidemic of chancroid. 587 cases (author's transl)].

Between 1973 and 1979, 673 cases of chancroid were diagnosed in the authors' Department at the hôpital Saint-Louis, Paris. Therapeutic results could be assessed in 587 patients of whom 297 were treated with daily intramuscular injections of 1 g streptomycin sulphate and 290 with co-trimoxazole, 4 tablets per day. All patients were completely cured within 10 to 20 days, irrespective of the therapeutic regimen. Needle aspiration, repeated if necessary, of purulent lymph nodes is recommended, as it prevents surgical drainage which would delay healing.

Adult↗
PubMed1982

[Detection and incidence of hepatitis in secondary syphilis. Seventy case-reports (author's transl)].

Biologic hepatitis is common in secondary syphilis. Six cases are reported, in which stereotyped biologic changes were found. These consisted of very high alkaline phosphatase levels and gamma GT levels, with definite inflammation. Cytolysis was moderate or absent. Diagnosis can be established when these biologic anomalies are associated with strongly positive serologic tests for syphilis and rapid recovery under adequate treatment. In these cases, hepatic biopsy is unnecessary.

Hepatitis↗
PubMed1982

[Bacterial endocarditis : lack of diagnostic value of immunological investigations (author's transl)].

To evaluate the diagnostic help afforded by immune determinations in feverish valvular patients, we prospectively determined: total hemolytic complement, cryoglobulin, rheumatoid factor, circulating immune complexes and direct skin immunofluorescence. Twenty patients entered the study, twelve with bacterial endocarditis, six without any bacteremia and two septicemic patients without endocarditis. We detected at least one immune abnormality in 10/12 endocarditis patients: - in 7/11 (64 p. cent) circulating immune complexes; - in 3/12 rheumatoid factor; - in 3/12 positive fluorescence in dermal vessels (IgM-C3); - and in one patient an IgG lupus-like band in the membrane basal zone. We also found circulating immune complexes in 3/4 patients without bacteremia and in 1/2 septicemic patients. We conclude that, in our small prospective study, immune abnormalities are frequent in bacterial endocarditis patients but their diagnostic values is rather limited : their absence do not rule out endocarditis and they can be present in many other febrile disorders.

Adult↗
PubMed1982

[Atopy and associated diseases].

In this study of the literature, the authors review the possible association between atopy and other conditions. The mostly reported observations are related to atopic dermatitis, but there is also some real relationship with respiratory allergy: this is true for mucoviscidosis. Some association are significant and interesting from the pathogenetic point of view: they may be classified under three headings (digestive and renal diseases, immunologic disturbances). Therefore, this study refers to intestinal absorption disturbance, gluten sensitive enteropathy, dermatitis herpetiformis, colic diseases, and also to glomerulopathies, immediate and delayed hypersensitivity deficiency and polymorphonuclear functional deficiency. Other associations do exist, but the low number of cases and the absence of a common pathogenesis allow no conclusion to be drawn (ectodermal anidrotic ectodermal dysplasia, Dubowitz syndrome). Some of them are certainly only fortuitous: this should be more definitely established by later studies. Some diseases may be accompanied by an eczematiform dermatitis (phenylketonuria, anomalies of histidin metabolism). Frequency of associations with alopecia areata and dominant ichthyosis vulgaris is also discussed. This review gives the possibility of emphasizing the absence of statistically significant hematopathic evolution of atopic dermatitis and calls attention on the Wiskott-Aldrich-syndrome as a model for the studies on atopy.

Agammaglobulinemia↗