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Biomedical subjects

J C Richard

Publications and source records attributed to J C Richard.

28 records · Page 2Linked to original sources

[70 patients operated on for sciatica without herniated disk].

Seventy patients suffering from sciatica were operated in whom no disc herniation was found. In 42 instances, compression of bony origin was found. These cases were either due to general narrowing of the spinal canal with signs in the distribution of several roots with neurological intermittent claudication, or to narrowing of the lateral recess or intervertebral foramen with involvement of only one root. Decompressive surgery was always beneficial for pain. In 20 instances a disc was found to be only bulging; disc excision was performed in 17 of these patients. In 8 instances, no abnormality was found. Some patients were nevertheless cured by disc excision, a single laminectomy being useful. The incidence of additional psychological problems is discussed. It is concluded that the clinical signs should guide the surgeon rather than the radiological findings in decisions for surgical treatment. Patients who have been correctly treated by conservative means for an adequate time should be systematically operated on if they have not shown sufficient clinical improvement.

Adult↗

[Fixation of fractures of the fifth metacarpal (author's transl)].

The authors describe the treatment which they recommend for fractures of the fifth metacarpal. After a brief description of fractures of the proximal end of the diaphysis and of the head of the bone, they study in detail fractures of the neck of the fifth metacarpal. They found that conservative treatment is not very successful but that internal fixation tends to have iatrogenic complications. They recommend a transverse pinning of the bone after reduction by manual traction. Two or three pins are driven from the fifth to the fourth metacarpal through the head and the shaft. This treatment allows early mobilisation.

Bone Nails↗

Amiodarone-like haemodynamic and non-competitive antiadrenergic properties of a benzoyl-indolizine.

1. 2-Ethyl-3-(4-gamma-di-n-butylaminopropoxy-benzoyl)-indolizine hydrochloride (L 9394) induced in the ananesthetized dog a marked and long-lasting decrease in heart rate together with a transient reduction in blood pressure. 2. L 9394 decreased Robinson's index, an effect which suggests that the substance reduces the oxygen requirements of the heart. 3. L 9394 markedly increased coronary arterial blood flow. 4. L 9394 is endowed with non-competitive antiadrenergic properties. 5. L 9394 did not impair cardiac function since cardiac output and stroke volume increased appreciably during the initial phase of action and did not fall below the control values at any time thereafter. 6. The overall haemodynamic properties of L 9394, which were similar to those of amiodarone, are considered to be potentially valuable for the long-term treatment of angina pectoris.

Adrenergic beta-Antagonists↗

[Contribution of computed tomography to the diagnosis of benign tumors of the liver].

Computed tomography is a recently introduced, nonaggressive method of radiological investigation that can contribute to the study of hepatic tumors. Information obtained by using a third generation apparatus in six cases of benign hepatic tumor is reported, and compared with operative findings in five cases. The principal aspects, common to both ultrasonography and computed tomography examinations, are compared within the context of the pathological findings. Computed tomography is of value as a complementary investigation to reduce any possible insufficiency of ultrasonography examinations or to supply supplementary information during pre-operative tests.

Adult↗