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J C Huber

Publications and source records attributed to J C Huber.

135 records · Page 8Linked to original sources
PubMed1982

[Premature rupture of membranes, fetal outcome, management of delivery (author's transl)].

In 764 gravides from totally 1738 women, which delivered 1977 in our hospital, happened a premature rupture of membranes. 319 patients had a spontaneous (SPR), 454 an artificial premature rupture of membranes (APR). Comparing the number of complications, the perinatal situation and the maternal behaviour, so you will find a significant difference between SPR and APR. The fetal outcome of the children, born after APR was better then born after SPR. The same is valuable as for the operative management of delivery. The perinatal morbidity after APR was nearly equal to the situation after normal rupture of membranes. Therefore you can see, that the bad experiences are more valuable for the SPR.

Delivery, Obstetric↗
PubMed1981

[The influence of beta-mimetics on foetal pulmonary maturing (author's transl)].

Amniocentesis was carried out in 99 patients between the 31st to the 32nd gestational week in order to determine lung maturity. We subdivided the patients into 5 groups 11 women were treated with Hexoprenaline, 12 with Ritodrine, 26 with Dexamethason for acceleration of lung maturity, 23 with Dexamethason and beta-mimetics and 27 women were controls. A significant rise of surfactant factor measured by surface tension by means of the Wilhelmy-balance could be demonstrated in the two groups receiving glucocorticoids, whereas in the other groups the rise of surfactant factor corresponded with the usual increase due to age of gestation. But concerning the incidence and intensity of RDS and intensity, the best results were observed in the group with Dexamethason only. Increase of surfactant factor and incidence of RDS in groups with tocolytics and in the controls were similar, therefore we conclude, that beta-mimetics do not have an influence on lung maturity. A relatively high incidence of mild RDS-cases in the group of Dexamethason combined with tocolytics should be a warning to use both drugs routinely together.

Adrenergic beta-Agonists↗
PubMed1981

[The cardiotocogram in a woman's emotional experience: aid to more pleasurable experience of delivery or technological bugbear? (author's transl)].

Immediately after delivery 80 women were asked about her impression of cardiotocography (CTG) during labor. 97% of the primigravidae (PGR) and 83% of the plurigravidae (PLG) believed, that every delivery should be observated by CTG. Only 3% of the PRG an 14% of PLG found it necessary only in complicated delivery. Unnecessary was the fetal heart rate observation found in 3% of the PLG, but not in one case of PRG. Very important for the psychological situation of women under birth is the information about the use of CTG. Our results show the great agreement of the patients about this perinatal observation method.

Emotions↗
PubMedDate not supplied

Estrogen does not induce the calcium-dependent nitric oxide synthase in cultured human uterine endothelial and myometrial smooth muscle cells.

In many tissues, estrogen-induced vasodilatation is mediated, at least in part, by the release of nitric oxide (NO). We determined whether human myometrial endothelial and smooth muscle cells express estrogen receptors (ERs) and whether endothelial NO synthase (eNOS) expression in these cells was affected by 17beta-estradiol (10[-13]-10[-6]M). ER was strongly expressed in myometrial smooth muscle cells but was absent from endothelial cells. Expression of eNOS mRNA was strong in endothelial cells, but weak in muscle cells. 17beta-estradiol administration for 24 or 72 h failed to increase eNOS in both cell types. Thus, an increase of human uterine blood flow by estrogens appears not to be mediated by stimulation of myometrial eNOS expression.

Adult↗
PubMedDate not supplied

[Course of pregnancy of insulin-dependent diabetic patients 1978-1985 at the 1st Vienna University gynecologic clinic].

Perinatal mortality and morbidity in infants of diabetic mothers have declined continuously during the past decades, due to advances in prenatal care, obstetric management and intensive neonatal care. This retrospective study reports on complications during pregnancy and fetal outcome in those insulin-dependent-diabetic (IDDM) pregnancies admitted to our institution from 1978 to 1985. Age, weight, prepregnant weight and weight-gain of those patients are compared with normal uncomplicated pregnancies (of the same period). In the diabetic group we noticed a high incidence of abortion (30%) as well as a high frequency of previous stillbirths (19%). In the majority of cases delivery was achieved by the 38th week of gestation the mean birth weight and length being 3,144 g and 48.5 cm respectively. 22% of the cases were delivered by cesarean section. The diagnosis preeclampsia was made in 15 patients, in 4 cases we observed a placental insufficiency, 11 women presented with premature labor and there was one fetal death. 44 newborns (63.8%) had a birthweight between 2,500 g and 4,000 g, 15 infants were below 2,500 g (21.7%), 10 infants weighed more than 4,000 g (14.5%), 5 of them displayed cushingoid features. 3 cases were complicated by hypoglycemia, 3 infants were dystrophic at birth and there was one major congenital anomaly. The incidence of neonatal respiratory distress syndrome was extremely high, 12 milder cases could be managed without ventilation therapy, 4 severe cases had to be given full respiratory support.

Austria↗
PubMedDate not supplied

[Hepatitis B screening in pregnancy].

At the I. Department of Obstetrics and Gynecology, University of Vienna, between April 1, 1985 and September 30, maternity patients between 24 and 28 weeks of gestation had their blood tested for hepatitis B. Out of 167 patients screened for hepatitis B, three had a positive hepatitis B surface antigen test (1.8%), nineteen a positive anti-hepatitis BsAg test. Two patients were positive for anti-hepatitis BeAg (1.2%), one was positive for hepatitis-BeAg (0.6%). The presence of hepatitis BeAg conveys a higher infant attack rate. Yet even in the absence of the antigen and/or the presence of anti-hepatitis BeAg, infection may lead to a fatal outcome. Also, if the mother is a carrier, risk of acquiring the infection because of chronic exposure is present. Therefore the question and possible need for routine Hepatitis B-screening during pregnancy arises, not only in maternity patients at high risk for hepatitis B.

Adult↗
PubMedDate not supplied

[Significance and incidence of risk factors in pre- and dysmaturity].

Anamnestic and clinical data of 10 654 deliveries were related to premature and dysmature pregnancies. The aim of the study was to get a correlation between special data on the one hand and pre- and dysmaturity on the other hand. The risk of dysmaturity is the highest in gravidae with a gestosisscore of more than 4. The risk of prematurity is the highest in gravidae with bleedings during pregnancy. The most frequent symptom in prematurity was a high cervix-score. It occurred in the prematurity collective in 40.7%. In the dysmaturity collective occurred the abuse of nicotine in 32.9%. Some symptoms have a high prognostic value for a pathological pregnancy, but it was impossible to develop a high risk score following these data. An high specificity was connected with a low sensitivity and vice versa.

Female↗
PubMedDate not supplied

[Antepartum and intrapartum cardiotocographic changes in pregnant women with diabetes mellitus].

In 69 insulin-dependent diabetic patients antepartal as well as intrapartal CTG's were evaluated retrospectively according to Fischer and Hammacher scores, revealing a marked decrease or a lack of decelerations together with a limitation of the oscillation amplitudes in the antepartal CTG. These show a marked increase during the last weeks of pregnancy. Intrapartal decelerations similar to variable dips are far more frequent. The same alterations, though less marked, are in part also found in latent diabetics. Owing to the small number of patients, and to a lack of literature in this field, no definitive conclusion can be drawn yet. Thus, prospective studies will still have to be carried out on a larger scale.

Female↗