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Biomedical subjects

J C Huber

Publications and source records attributed to J C Huber.

At least 109 records · Page 6Linked to original sources
PubMed1994

[Placebo-controlled study of melbrosia in treatment of climacteric symptoms].

In a placebo controlled randomized trial we evaluated the efficacy of melbrosia in women who suffered from severe menopausal symptoms. We could show that there was hardly no difference in the change of biochemical parameters, but we found out that the decrease of menopausal symptoms (headache, urinary incontinence, dry vagina, decreasing vitality) was significant in women who did undergo melbrosia medication compared to those who just took placebo. Due to our investigations we reasoned that melbrosia is especially appropriate to women who do not want and who do not need hormone replacement therapy, but who do suffer from menopausal symptoms.

Adult↗
PubMed1993

[Prolactinoma after craniocerebral trauma].

A female patient, now twenty-four years old, suffered from a severe cerebral contusion in 1983 as a result of a car accident. At the time of the accident, she had a regular menstrual cycle. Since 1985, she has contracted oligomenorrhoea and since 1988 secondary amenorrhoea. In 1988, we diagnosed by CT-scan and NMR-imaging an excessive hyperprolactinaemia caused by a pituitary adenoma. Neither surgical intervention, nor conservative medication could reduce the prolactin level to normal. We suspect, that there is an association between the cranial injury and the appearance of the pituitary tumour.

Adult↗
PubMed1992

[Effect of high performance sports on female menstrual cycle exemplified by windsurfing].

Questionnaires were sent to all female members (n = 60) of the Austrian Funboard Association (funboard = the most athletic windsurfing class). They included questions about the menstrual cycle, physical capacity, libido and performance dependent on the particular cycle phase. There was no significant libido or capacity peak, neither for the windsurfers nor for a normal collective (n = 100); on the other hand there was an evident low during menstruation. A mean length of the menstrual cycle of 26.5 +/- 2.8 days and a bleeding time of 4.4 +/- 1.2 days were found, while metrorrhaghia and dysmenorrhea were less frequent than in the normal collective. One reason for these findings could be that physical activity reduces dysmenorrhea.

Adult↗
PubMed1990

[Contraception in Austria].

952 sexual active women between 15 and 44 years were investigated for their contraceptive behaviour. In 42% the pill was the first choice followed by the condom in 16%. 18% of all sexual active women in this age group did not use any contraceptives. Therefore the rate of unplanned pregnancies was very high: 34% reported about such unplanned pregnancies in their history. The main sources for informations in contraception are the gynecologist and the partner, but not the parents or the newspapers. Nearly half of all women did not know how the pill really works and quite a lot has still the opinion that there are really harmful side effects of oral contraceptives.

Adolescent↗
PubMed1989

[The course of atrial natriuretic peptide, aldosterone and antidiuretic hormone in normal pregnancy].

Atrial natriuretic peptide (ANP), consisting of 28 aminoacids, is a recently discovered cardiac hormone involved in blood-volume homeostasis. Pregnancy is associated with an increase in blood volume expansion, therefore an increase in ANP-concentration would have been expected. To test this hypothesis ANP, Aldosterone and Vasopressin, concentrations of 229 women with normal pregnancies at different gestational ages were measured and compared with values found in a non-pregnant control group of 24 women. Mean plasma ANP was increased during pregnancy, but significant differences were noted only after 36 weeks of gestation. Also plasma aldosterone increased significantly during pregnancy, whilst vasopressin levels showed no significant change compared to the non-pregnant group.

Adolescent↗
PubMed1989

[The development of cycle monitoring in Vienna].

Cycle monitoring is performed by daily determination of LH, estradiol and sonography of the ovaries, up to day 10 of the cycle. Endocrinological disturbances can be detected by this monitoring: a missing LH peak, in spite of a normal estradiol concentration, can be interpreted as a cause of infertility. Also an insufficient growth of the follicles can interfere with fertility. The dissociation between LH peak and estradiol plateau in the serum is still open to debate.

Adult↗
PubMed1988

[Vaginosonographic imaging of the endometrium of postclimacteric females].

Vaginal sonography of the endometrium is a new method of controlling the substitution therapy with oestrogen and progesterone during the postmenopausal period. The advantages of transvaginal ultrasonic diagnosis are that the uterus can be seen from the fornix vaginae, that it is situated at close range, and that the examination can be conducted whether the bladder is filled or not. The differences in thickness and structure of the endometrium, and the limitation to the surrounding myometrium, enable sonographic detection of most of the changes of the endometrium during the postmenopausal period. In our first group of patients, we found an endometrial carcinoma in 2 out of the 60 women with postmenopausal metrorrhagia. The findings were confirmed histologically. Women who have regular bleedings while undergoing hormone therapy during the postmenopausal period, show signs of proliferation in the endometrium under oestrogen therapy and signs of secretion under progesterone therapy.

Climacteric↗
PubMed1988

[Correlation of maternal androgens in early and late pregnancy. A correlation with fetal size and sex].

In the course of prospective investigations blood was withdrawn for steroid analysis in 50 gravidae between 12th and 16th and between 26th and 30th week of gestation. The levels of androstenedione, testosterone, dehydroepiandrosterone sulfate, 17-hydroxyprogesterone and sex hormone binding globuline were determined by radioimmuno-assay evaluating a possible correlation between the androgen values and growth retardation or the sex of the fetus. Neither during the early nor during the late period of pregnancy significant differences concerning the androgen levels could be detected among both sexes. Worth mentioning is the significant decrease of the DHEA-S levels during the late period of gestation, which occurred in both groups, whereas the androstenedione, testosterone and especially the 17-OH-P levels showed a significant increase. The SHBG values almost did not change at all.

17-alpha-Hydroxyprogesterone↗