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Biomedical subjects

J C Harvey

Publications and source records attributed to J C Harvey.

At least 55 records · Page 3Linked to original sources
PubMed1992

Ethical issues and controversies in assisted reproductive technologies.

The current ethical issues and controversies concerning in vitro fertilization revolve around micromanipulation of the gametes, cryopreservation of the fertilized ova, selective termination in multiple pregnancies, surrogacy, and gamete donation. At the basis of these ethical issues is the philosophic question of personhood, or the term "human person," and the consideration given to the normal weight that is ascribed to the various forms of living matter that are found in the process of development after human spermatozoa have been placed together with harvested oocytes in the petri dish. The papers of very special importance and special importance written during the past year on these ethical problems are listed and classified. The summaries of their arguments and positions on these problems are enumerated.

Abortion, Induced↗
PubMed1991

Squamous carcinoma of the distal esophagus: a survival study.

A survival study for squamous carcinomas of the distal esophagus treated by the Southern California Permanente Medical Group in the interval of 1954 to 1988 was undertaken. We found radiation therapy and surgery equally efficacious in terms of cure for patients without distant disease and performance status sufficient to tolerate treatment. We did not find survival benefit for patients treated with palliative surgery, and plan less invasive endoscopic means along with chemotherapy and radiation for palliation, reserving surgery for special circumstances.

Adenocarcinoma↗
PubMed1991

Results of multiple pulmonary resections for metastatic osteogenic sarcoma after two decades.

A 20-year follow-up of children who had complete resection of pulmonary metastases from osteogenic sarcoma of the extremities was undertaken. Four of six 10-year survivors survived more than 19 years even with multiple metastases and as many as nine thoracotomies. Fifty percent of the 10-year survivors developed second primary cancers during the second decade of follow-up.

Adolescent↗
PubMed1991

Endobronchial carcinoid and mucoepidermoid carcinoma in children.

Endobronchial neoplastic disease is rarely encountered in patients under 20 years of age. The great majority of these lesions are carcinoids or mucoepidermoid carcinoma. Symptoms are secondary to bronchial irritation and manifest as recurrent pneumonitis, hemoptysis, persistent cough, reactive airway disease, and chest pain. Early bronchoscopy reliably enables identification and may prevent harmful sequelae resulting from delay in diagnosis. Retrospective data from four cases collected from the Tumor Registry in the Southern California Kaiser Permanente Medical Group is presented and a review of the literature is discussed.

Adolescent↗
PubMed1991

Opening doors to the needy. An archdiocese coordinates a physician referral network.

The availability and accessibility of healthcare to those unable to pay is deteriorating rapidly. One place this is clearly apparent is in our nation's capital, where extremes of poverty and wealth abound. In an effort to improve access to healthcare for the poor, homeless, and medically indigent in the Washington, DC, area, the Washington Archdiocese Health Care Network (AHCN) was formed in 1984 under the leadership of Card. James A. Hickey. The AHCN is a coordinating agency that refers people in need to physicians, physical therapy and rehabilitation services, and dentists who have agreed to volunteer their services to this vulnerable population. The formation, operation, and continuation of the AHCN are performed by five members of one steering committee on behalf of the hundreds of volunteers who make it work daily.

Catholicism↗
PubMed1991

Resection of residual mediastinal germ cell masses with the Cavitron ultrasonic surgical aspirator.

Residual mediastinal masses after chemotherapy for germ cell tumors should be resected. Complete excision of bulky residual masses may sometimes be difficult because of problems with exposure in the region of the great vessels and important nerves. Two cases are presented in which the Cavitron ultrasonic surgical aspirator (Valleylab Inc., Surgical Systems Division, Stamford, Conn.) facilitated excision of large masses after intensive chemotherapy. We found that the collapsed pseudocapsule remaining after aspiration of tumor mass allowed early improved exposure and safer dissection from neighboring vessels and neural structures. Complete excisions were accomplished and no viable tumor was found, so that the patients were spared the immediate need for further therapy. Both had uneventful recoveries.

Adult↗
PubMed1991

Squamous carcinoma of the mid-esophagus. A survival study.

A survival study for squamous carcinomas of the mid-esophagus treated by Southern California Permanente Medical Group in the interval of 1954 to 1988 was undertaken. Radiation therapy and surgery were equally efficacious in terms of 5-year survival for patients without distant disease and performance status sufficient to tolerate treatment (11% and 16%, respectively). There was no survival benefit for patients treated with palliative surgery. Less invasive endoscopic means along with chemotherapy and radiation for palliation are recommended except for special circumstances. Optimal treatment combinations remain to be discovered.

Carcinoma, Squamous Cell↗
PubMed1991

Thoracic surgery in the AIDS patient.

AIDS is a syndrome caused by HIV. The virus is spread by homosexual or heterosexual transmission and by infected blood or certain body fluids. Respiratory infections are the commonest cause of death, and diagnosis may be difficult. The fiberoptic bronchoscope (FOB) plays an essential role in diagnosing respiratory infections in AIDS and is important in minimizing the need for open lung biopsies. Various problems require thoracic surgical consultation and treatment. We do not consider it ethical to deny these patients help. There can be no "double standard" in the care of patients in the hospital or in the operating room since any of our patients may have HIV without our knowledge.

Acquired Immunodeficiency Syndrome↗
PubMed1990

Effective palliation for inoperable esophageal cancer using intensive intracavitary radiation.

In a pilot study between May 1988 and May 1989, ten consecutive patients with advanced esophageal cancer were treated with a short intensive course of intraluminal curietherapy without external beam irradiation at the Kaiser Permanente-Los Angeles Medical Center. Nine of ten patients achieved effective palliation comparable to that of standard external beam teletherapy from other series. Most patients had already failed other palliative modalities including chemotherapy, laser debridement, dilation, and electrocautery. The duration of response was generally longer than with these techniques. All patients completed therapy, and tolerance was excellent. Intraluminal irradiation is an attractive, effectual therapeutic alternative, especially in patients with advanced local or distant disease unlikely to tolerate 5 to 7 weeks of external beam therapy.

Aged↗
PubMed1990

Adenocarcinoma of the esophagus: a survival study.

A 35 year review of adenocarcinomas of the esophagus was undertaken. We found the disease to be one of increasing incidence afflicting white males disproportionately. Risk factors remain to be clarified. Radiation therapy in curative doses and complete resection were competitively effective in terms of long-term survival. No survival advantage was found with palliative surgery compared with other means of therapy. Optimal combinations of treatment remain to be discovered.

Adenocarcinoma↗
PubMed1990

Malignant pleural mesothelioma: a survival study.

Ninety-four patients with malignant pleural mesothelioma were treated at Southern California Permanente Medical Group Facilities between 1965 and 1988. This retrospective analysis of survival in these patients is compared according to surgical and/or supportive management. Group I patients received supportive care only, including pleurodesis as needed. This group included the majority of patients. Group II patients were managed largely with debulking procedures including decortication and pleurectomy. Group III patients received extrapleural pneumonectomy. This group included the two long-term survivors of the entire group. This study of survival points out the need for a cooperative protocol as well as the consistent use of proper modern preoperative staging in an attempt to select patients who benefit from extrapleural pneumonectomy.

Adult↗
PubMed1990

Adenocarcinoma arising in Barrett's esophagus.

A review of nine adenocarcinomas of the esophagus arising in Barrett's epithelium was undertaken. We found the disease among white males disproportionately. Risk factors and incidence rate remain to be clarified. Only one patient was in a surveillance program and only he had carcinoma discovered "early." He still survives while only one of the eight whose diagnosis followed investigation of symptoms remains alive.

Adenocarcinoma↗
PubMed1990

Mediastinal hibernoma, a rare tumor.

Hibernoma is an uncommon soft tissue tumor that is derived from the remnants of fetal brown fat. Review of the world medical literature revealed 90 cases, 6 of which were intrathoracic. We present the seventh case of intrathoracic hibernoma; in this case, the hibernoma was within the mediastinum without direct invasion of other structures.

Adolescent↗
PubMed1986

Phenytoin-induced systemic granulomatous vasculitis.

Much has been written about adverse effects accompanying the use of phenytoin. However, the rare occurrence of systemic vasculitis induced by this drug has only been the subject of sporadic case reports and has not truly been characterized as a definitive entity. The high fatality rate of this complication is a proof of its severity. A case of multiorgan necrotizing granulomatous vasculitis related to the use of phenytoin is reported and the clinicopathologic aspects of seven similar cases assembled from the literature are summarized and discussed. The most commonly affected patients are elderly black men who present with skin rash, fever, and, frequently, eosinophilia. Tissue examination discloses systemic vasculitis that is often granulomatous and involves mainly the liver, kidneys, and spleen. Immediate recognition of this diagnosis is stressed, since proper treatment may reverse a fatal clinical course.

Adult↗