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Biomedical subjects

J C Hart

Publications and source records attributed to J C Hart.

At least 55 records · Page 3Linked to original sources
PubMed1977

Structural changes in the outer retinal layers following blunt mechanical non-perforating trauma to the globe: an experimental study.

Structural changes in the external retinal layers of pigs' eyes that had previously been subjected to blunt non-perforating mechanical injuries have been described. Within minutes of trauma fragmentation of the photoreceptor outer segments and damage to the retinal pigment epithelium was recorded in areas of retina adjacent to the missile impact site on the sclera. One week after injury the disrupted photoreceptor outer segments disappeared, and the inner segments came to lie adjacent to the retinal pigment epithelium. Evidence of regeneration of photoreceptor outer segments was noted 2 weeks later.

Animals↗
PubMed1977

Adult toxocariasis. Uniocular retinal lesions in the 20- to 50-year age group.

Uniocular posterior polar lesions thought to be characteristic of suspected adult ocular toxocariasis have been observed in a group of eight patients whose ages ranged from 20 to 50 years. Six patients had positive fluorescent antibody tests for Toxocara species, whereas control serological studies showed that only 4% of healthy adults in the same age group had positive fluorescent antibody responses. All the patients with clearly defined progression of their retinal lesions had positive fluorescent antibody tests. In two patients positive tests reverted to negative within 2 years.

Adult↗
PubMed1976

Ocular toxocariasis in adults.

Human infection by toxocara larvae has been thought to be predominantly a disease of young children, but the percentage of the population with antibodies to this nematode worm has recently been shown to increase with age. Although a definite diagnosis of ocular toxocariasis can be made only by identifying the larva histologically, the evidence in three cases presenting with recent uniocular loss of vision strongly suggests that adults may also be affected. The lesions noted on ophthalmoscopy closely resembled toxocaral granulomata in children. Toxocaral fluorescent antibody tests were positive in each case.

Adult↗
PubMed1975

A programme for collaborative influenza surveillance. A report of a working group of the Public Health Laboratory Service.

A surveillance programme is described which is intended to assess the effects of influenza virus infections on communities at large by collating influenza virus isolations and consultations for respiratory infections from general practices with new claims for sickness benefit and deaths from all causes. Particular importance is attached to relating virus isolations to symptomatic respiratory disease seen in practices of known age and sex structure.

Acute Disease↗
PubMed1975

Retinal opacification after blunt non-perforating concussional injuries to the globe. A clinical and retinal fluorescein angiographic study.

Fluorescein angiographic studies are reported on fifteen patients presenting with retinal opacification after blunt mechanical non-perforating injuries involving the eye. In patients who subsequently regained full visual function and in whom complete resolution of the retinal changes occurred, retinal fluorography carried out less than 24 hours after injury revealed no abnormal features. In cases with more prolonged visual disability, retinal fluorescein examinations may, however, reveal damage to the retinal pigment epithelium before this becomes apparent on routine ophthalmoscopy, or the existence of impaired perfusion through the retinal vessels. It is suggested, therefore, that retinal fluorescein angiography has a role in assessing the visual prognosis in patients presenting with traumatic retinal oedema.

Adolescent↗
PubMed1973

Outbreak in Bristol of conjunctivitis caused by adenovirus type 8, and its epidemiology and control.

In an investigation of an outbreak of adenovirus type 8 infection involving over 40 people it was found that the infection spread initially within the eye hospital, but subsequently involved several family contacts and two local hospitals for mentally subnormal patients. Presumptive diagnosis should be possible before subepithelial opacities have developed provided an adequate history is taken, and had that been done in this outbreak it is reasonable to suppose that many cases could have been prevented.

Adenoviridae↗