[Studies on selected parameters of immunological reactivity in children with neuroblastoma].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to J Bozek.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The tumours of newborn period are usually of disontogenic origin and in some percentage of cases can be diagnosed directly after the child is born. Some of them are urgent for surgery. The authors present 22 own cases operated at the age of 4-28 days of life, in the period 1962-1977. Ten of them were sacro-coccygeal tumours. The indications for surgery were the following: tumours of morphological or clinical malignancies, big tumours disturbing motority of the child, tumours ruptured, bleeding, quickly growing and disturbed renal function. Positive result of the treatment was received in 80%. The authors suggest that cases have to be operated in highly specialized centres devoted to surgical treatment of malignant tumours in children.
The authors present 5 cases of mediastinal neuroblastoma in children with the syndrome of medullar compression. The problems of the diagnosis, the treatment and the prognosis are discussed. The attention is called to the rapidity of neurological signs progression and the diagnostic significance of cerebro-medullar fluid and radiological examinations (thoracic and vertebral X-rays and myelography). The necessity to decompression (laminectomy) as quick as possible is underlined. The authors indicate that these cases must be evaluated and treated in the complex way and the tumour advancement, neurological disorders, appropriate orthopedic supplies and rehabilitation must be considered respectively. The serious prognosis, especially in children above one year of life, is emphasized.
Explore the source record for details and available documents.
The authors present their own clinical material of retinoblastoma in children treated in the Clinical Department of Child Oncology of the National Research Institute of Mother and Child in Warsaw, in the years 1962-1976. Analyses of epidemiological and clinical data of 47 cases was done, and a four-stage classification was established. Case report of bone metastases of retinoblastoma from material is presented with some conclusions concerning treatment and prognosis in cases with bone metastases.
During the years, 1962 through 1975, 27 children with sacrococcygeal teratomas were seen at the Oncological Department of the National Research Institute for Mother and Child in Warsaw. 13 teratomas were benign and 14 were malignant. Surgical removal through a sacral approach was the basis of the treatment. In the presacral tumors with great diameter two-phase method was performed (the first phase--trans-abdominal excision of the tumor and the second phase--excision of remnant tumor's pedicle with coccygeal bone resection). Monodrug chemotherapy (Cyclophosphamide, Actinomycin D) in malignant tumors was without effect. In the group of benign teratomas are alive 11 children, in the group of malignant teratomas only one child survived. Some profits are expected from the multidrug chemotherapy ( Methotrexate , Cyclophosphamide, Actinomycin D) associated with radiotherapy, this can make operable primarily inoperable tumors.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The basic informations concerning pathology and clinical stagging of malignant tumours localized in urinary bladder and prostatic gland are introduction to proper presentation of own material collected and treated in the years 1962-1977. The material consists of 23 cases of rhabdomyosarcoma localized in minor basin. Formerly in the years 1962-1975, the basic form of treatment was surgery with/or radiotherapy. Chemotherapy that was given accidently in special indications as single dose or for a short time. Since 1975, we have started with systematic multidrug chemotherapy (VAC) used as an important part of complex therapy. Finally the authors discuss the place of chemotherapy in complementary treatment on the base of the literature and their own experience.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Introductory data on nephroblastoma occurence in children is followed by a general discussion on the methods of procedure used in treatment of these tumours in the last century. Then the author gives definite indices how to treat the disease surgically. In the description all groups of clinical advancement (promotion) of the neoplasm and the age of children are mentioned. The paper is supplemented by 20 Polish as well as foreign works (bibliographies).
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.