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Biomedical subjects

J Bozek

Publications and source records attributed to J Bozek.

At least 19 recordsLinked to original sources
PubMed2004

Dynamically and quasiforbidden transitions in photoionization of open-shell atoms: a combined experimental and theoretical study.

Completely fine-structure-resolved photoelectron spectra produced from sodium atoms selectively excited into the Na* 2p(6)3p (2)P(1/2) and (2)P(3/2) states were obtained using a third generation synchrotron source in conjunction with laser pumping and high-resolution spectrometry. The spectra show dramatically different behaviors. The strong variations observed in the regions of the Na+ 2p(5)3p (1,3)L(J) photolines and the Na+ 2p(5)4p (1,3)L(J) shakeup satellites are explained within a generalized geometrical model, accounting for the intermediate angular momentum coupling in the ionic states.

Journal Article↗
PubMed2002

Experimental link of photoionization of Sc2+ to photorecombination of Sc3+: an application of detailed balance in a unique atomic system.

The principle of microscopic time reversal of physical processes, detailed balance, is widely used and depended upon in the theoretical community as a connection between photorecombination (PR) and photoionization (PI). This paper reports on a novel use of detailed balance and the comparison of experimental results obtained by two very distinct techniques to determine both the metastable fraction of an ion beam and partial Sc3+ PR cross sections and partial Sc2+ PI cross sections for the ground state and for two metastable states. The Sc2+ to Sc3+ system presents a unique opportunity to obtain comprehensive state-selective information by combining results from PR and PI experiments.

Journal Article↗
PubMed2000

Angle-resolved photoelectron spectrometry studies of the autoionization of the 2s(2)2p 2P triply excited state of atomic lithium: experimental results and R-matrix calculations

We have measured the angle-resolved energy dependence of the electrons emitted over the energy range of the triply excited 2s(2)2p 2P lithium resonance using synchrotron radiation. We have also calculated the behavior of the angular distribution parameter beta using the R-matrix approximation. Experimental and theoretical results are in good agreement and show deep minima in the 1s2p (1, 3)P ionic channels. The energy at which the minima occur does not coincide with the resonance energy, but is shifted towards higher energy.

Journal Article↗
PubMed1991

Urinary dopamine/noradrenaline and dopamine/vanillylmandelic acid ratios as a reflection of different biology of adrenergic clones in children's neuroblastic tumors.

The results of calculations of urinary dopamine/noradrenaline (DA/NAd) and dopamine/vanillylmandelic acid (DA/VMA) ratios in 54 untreated children with neuroblastic tumors are reported. Thirteen patients were in the prognostically favorable group (stages I, II, and IV-S and ganglioneuroma [GN]), and 41 had advanced neuroblastoma (stage III and IV). Among patients with ganglioneuroma and favorable neuroblastoma (n = 13), of whom all were survivors, the urinary DA/NAd and DA/VMA ratios exceeded 1.8 in only 2 cases of stage IV-S and stage I, respectively. In the advanced neuroblastoma group, the DA/NAd and DA/VMA ratios exhibited a wide range of values, but among the stage III and IV survivors (n = 10), DA/NAd ratios greater than 1.8 were noted in only 3 patients. The DA/VMA ratio was not greater than 1.8 in those 3 patients. The mean DA/NAd and DA/VMA proportions in the population comprising all survivors were 1.8 +/- 2.7 (mean +/- SD) and 1.1 +/- 0.4, respectively. The same computations carried out in patients who died showed higher values, ie, the mean DA/NAd and DA/VMA ratios were 5.2 +/- 6.3 and 5.6 +/- 10.5, respectively, showing the difference in DA/NAd and DA/VMA ratios between prognostically favorable and unfavorable groups. Of 23 survivors, only 4 had DA/NAd ratios greater than 1.8 (17%), while 24 of 31 children who died (77%) had DA/NAd ratios was greater than 1.8. The reported results suggest dissimilarity in the catecholamine metabolism of adrenergic clones with respect to the stage of advancement of neoplastic disease.

Abdominal Neoplasms↗
PubMed1984

[Preliminary analysis and elaboration of the methods of study of the attitude of parents of children with neoplasms and the methods of psychotherapy and evaluation of physical fitness of these children].

The main purpose of this paper is presentation of chosen methods of reintegration into main stream from the point of psychological, social development and physical capacity, in children with cancer. These methods concern to: investigation of parents' attitude towards children with cancer, group psychological therapy, evaluation of general physical capacity of the children and their locomotion function. There were done preliminary analysis of parents' attitude of children with cancer in diagnostic period. It consists a trial in verification of chosen methods.

Adult↗
PubMed1984

[Preliminary elaboration of diagnostic methods for rhabdomyosarcoma in children].

The material basic for this paper consists of 24 children with soft tissue tumors, aged 1-16 years which were diagnosed in the Clinical Department of Child Oncology of the Institute of Mother and Child Warsaw. The diagnostic methods included: interview, physical examination, radiological examination (including CT), bone marrow punction histological investigation by means of fine needle punction and/or biopsy. These methods were sufficient in making a precise diagnosis and staging. The most frequent was stage III (16 cases). It comes from a fact of late diagnosis caused by non characteristic clinical picture. All common localisation was represented in this group (stage III including a cases of causel localisation in the heart.

Abdominal Neoplasms↗
PubMed1984

[Preliminary elaboration of the method of specimen collection using fine-needle biopsy in the diagnosis of rhabdomyosarcoma in children].

Fine needle punction proposed by Martin and Ellis in 1931, is a safe method of diagnosis by means of cytology making possible tumoral verification. In group of 24 children with RMS treated in Clinical Department of Child Oncology, Institute of Mother and Child Warsaw during last 2 years, fine needle punction was made in 7 cases. Precise diagnosis was possible after cytological examination in 2 cases. Non-precise diagnosis confirming malignant tumor only, was done in 3 cases. In resting 2 cases there were no material for evaluation, by means of cytology. Anyhow there was tissue material for histopathological examination. No complications in our material was observed. Fine needle punction is a safe method but requires personal experience of the surgeon and pathologist who performed cytological examination. Method seems to useful in advanced tumors when surgery is limited. Precise diagnosis is possible in short time, and early treatment can be done.

Adolescent↗
PubMed1984

[Preliminary elaboration of the method of complex treatment of rhabdomyosarcoma].

24 children with rhabdomyosarcoma were treated in Clinical Department of Pediatric Oncology of the Institute of Mother and Child, Warsaw during last 2 years. Complex therapy consisted of surgery, chemotherapy, radiotherapy and rehabilitation. Choice method of the treatment depends of stagging by Intergroup RMS Study. Basic method is surgery (radical excision with margin of neighbouring tissue). Modern multi-drug chemotherapy has changed strategy of the treatment by means of less extended surgery. Radiotherapy in RMS has to be mega-voltage what gives short time of irradiation and less complication. Rehabilitation as a component of complex therapy of RMS has to preserve function of treated organ and in cases after mutilated surgery becomes rehabilitated procedure.

Adolescent↗
PubMed1983

Life endangering tumors in the ENT region in children.

Forty children with life-endangering tumors localized in the ENT region were treated during the last 10 years at two clinics in Poland: the Oncological Clinic in Warsaw and the Otolaryngological Children's Clinic in Lódź. In this group there were 29 malignant tumors at different pathology, and 11 non-malignant tumors that became life-endangering because of their size and localization. These children were treated, dependent on the nature of the tumor, with surgery, chemotherapy and X-ray therapy.

Adolescent↗
PubMed1983

[Methods used in the diagnosis and treatment of rhabdomyosarcoma].

The authors present their own clinical material of 74 cases of rhabdomyosarcoma in children, treated in the years 1962-1980. The analysis consists of generally used methods of diagnosis and treatment. Diagnosis was made on the base of clinical, radiological and pathological examination. Treatment was established after stagging qualification and after actually used methods. The treatment based on surgery, radiotherapy, and simple drug chemotherapy was giving bad prognosis and good results was obtained in single cases only. Significant improvement in the results was obtained after multidrug chemotherapy introduced into combined treatment (40%).

Adolescent↗
PubMed1982

[Role of chemotherapy in the treatment of Wilms' tumor in children].

In the years 1962-1976, 168 children with nephroblastoma (Wilms Tumour) were treated in the Clinical Department of Child Oncology of the Institute of Mother and Child in Warsaw. In 150 cases, independently from surgery and radiotherapy, chemotherapy was performed. Our material was divided into 5 groups: a) without chemotherapy, b) chemotherapy with different drugs, c) chemotherapy with 1 course of Actinomycine D, d) chemotherapy with several courses of Actinomycine D, e) chemotherapy according to SIOP Trial. The results with reccurency free survival are as follows: a) 22,2%, b) 24,1%, c) 28,1%, d) 46,6%, e) 56,6%. In our material the best results were received with SIOP Trial chemotherapy.

Adolescent↗