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Biomedical subjects

J Biermann

Publications and source records attributed to J Biermann.

At least 37 records · Page 2Linked to original sources
PubMed1987

[An eicosapentaenoic acid-rich diet in relation to a reducing diet and physical training].

The effect of a mackerel diet alone or in connection with reducing diet and physical training has been tested during 4 weeks in 49 male patients with cardiovascular diseases undergoing a cure and in 45 males with healthy metabolism. 1st group: 15 persons with healthy metabolism, 240 g/die supplementary mackerel diet, no physical training; 2nd group: 16 cure patients with reducing diet (5,000 kJ/d), no mackerel diet, no physical training; 3rd group: 14 cure patients with reducing diet and a proportion of mackerels of 125 g/d, no physical training; 4th group: 19 cure patients with reducing diet and mackerel diet 125 g/d as well as daily swimming training (20 to 30 min). The decrease of beta-C and Apo B was most distinct in groups 3 and 4 and lay between 21 and 35%. The combination reducing diet with proportion of mackerels proved to be most effectively for the decrease of the atherogenic LDL and was superior to the monotherapies. A significant increase of the HDL (measured in alpha-C and Apo A) took place only in group 4 with simultaneous performance of physical training, alpha-C increased by 31 and Apo A by 8%.

Adult↗
PubMed1986

[Postprandial hyperlipemia, circadian rhythm and the stress test in lipid metabolism].

Functional tests and daily profiles allow more exact insights for the diagnostics and management of the therapy in disturbances of fat metabolism than the momentary establishment of the fasting lipids. Circadian rhythms are reported particularly for lipoproteins rich in triglycerides, triglycerides, HDL fractions, lipolytic and lipogenic enzymes. The postalimentary hypertriglyceridaemia depends upon the distribution and the composition of food as well as upon individual differences (e.g. sex). The connection to the HDL metabolism is of particular importance. The interaction of the lipoprotein fractions in the circadian course has still many open questions. Results with an oil tolerance test are presented and discussed.

Adipose Tissue↗
PubMed1986

[Optimizing therapy of arterial hypertension in a health cure].

On 514 male and female patients (average age 51.9 years) with arterial hypertension I and II according to WHO who had been admitted to cure a check-up of the efficacy of the current antihypertensive therapy and the compliance of the patients was carried out. At the beginning of the cure 15.5% of the hypertensives were normotonic, 30.2% with limiting value and 52.3% hypertonic. The analysis of the habit of intake of antihypertensive drugs revealed that only 48.4% of the patients before the cure had taken their medicaments according to the prescription of the physician. The main cause for unsatisfying results of the therapy is the bad compliance of the hypertensives, in our opinion a sequela of the often existing freedom from symptoms. Further causes we see in the irregularities of the intake of medicaments, particularly during shift-work, in wrong habits of nutrition and in a too passive way of life. At the end of the cure in 64.5% of all patients a normotonic stabilisation of the blood pressure was to be stated, 27.8% had limiting values, in 7.4% no stabilisation of the blood pressure into the normal or borderline region could be achieved. Under cure conditions modes of behaviour furthering the disease and wrong habits of life and eating can be changed. The cure gives good conditions by means of health-educational measures and using the motivation for an active way of life which is present in the patient at the end of the cure better to carry the aims of the medical treatment.

Antihypertensive Agents↗
PubMed1986

[Modification of disordered glucose metabolism by physical training of low intensity].

The effect of a 4-week perseverance training on the blood glucose concentration was investigated in 48 male patients with cardiovascular diseases (average age 50.1 years), in whom a disturbed glucose tolerance and a type II diabetes mellitus, respectively, was existing. According to random criteria the patients were divided into a running, swimming, ergometer and control group. In the training groups the intensiveness of the load was 50-60% VO2 max, the daily duration 20 min with a frequency of 5 times a week. The glucose tolerance test was performed with an oral load of 75 g pure grape sugar before and after the training period. The results of the investigations prove that by means of these relatively low load intensities an amelioration of the glucose tolerance can effectively be achieved.

Blood Glucose↗
PubMed1986

[Triglyceride profile following oil administration].

27 normolipaemic females (average age 33.5 years), 26 normolipaemic males (average age 40.2 years) and 29 male patients with cardiovascular diseases (average age 48.9 years) were examined. In all persons an oral tolerance test with 75% sunflower oil was performed. After 6 and 8 hours the control of the postprandial hypertriglyceridaemia was performed. The average fasting values and the postprandial deviations show a clear degradation--females, males, patients with cardiovascular diseases. Between the size of the triglyceride deviation after load with edible oil and the HDL-cholesterol concentration in the fasting serum there is a significant negative correlation in patients with cardiovascular diseases and in normolipaemic males, which is not to be recognized in the group of the normolipaemic females. The authors are of the opinion that HDL cholesterol is also an indicator for the speed of the destruction of triglyceride-rich lipoproteins. At the end of a 4-week swimming training of 20-30 minutes a day, 6 times a week, in the patients with cardiovascular diseases a significantly improved fat tolerance and thus a round increase of the lipolytic capacity could be proved.

Adult↗
PubMed1985

[The lipoprotein profile of hypertensive patients and its modification by 4 weeks of physical training during spa treatment].

Investigations of the lipoprotein spectre on 47 male patients with hypertension (mean 49.6 years) achieved a higher proportion of vasoaggressive lipoproteins than in 26 male healthy controls. With the exception of the genetically determined and familial forms respectively, we class the hyperlipoproteinaemia and the dyslipoproteinaemia with the acquired metabolic influences for the manifestation and the further development of a hypertension. By general aerobic perseverance training the hypertension as well as the hyperlipoproteinaemia can be positively influenced.

Combined Modality Therapy↗
PubMed1985

[Measurement and control of the intensity of endurance training in patient groups].

In 49 male patients at the age 34-62 years (means = 48.8) during the perseverance training in groups of patients the observation of the intensity aspired for was controlled by means of controls of the heart beat frequency with the help of long-term ECG and self-controls of the pulse rate by the patients. As a result of the long-term ECG controls could be established that the intensity areas aspired for was reached by the preponderant number of the patients or even transgressed, that the judgment of the self-controls of the pulse rate must be performed very critically and in their valuation a subjective and methodically caused measuring error must be taken into consideration. References were given the consideration of which shall lead to an improved observation of the intensity given during the perseverance training in groups of patients.

Adult↗
PubMed1985

[Specificity and sensitivity of lipoprotein lipids in normal persons and cardiovascular patients].

The amplitude of the determination of lipoprotein lipids and cholesterol quotients for the estimation of the atherogenic risk and the risk of myocardial infarction was investigated on 24 normal persons, 21 patients with overcome myocardial infarction, 47 hypertensives and 20 obese patients. Under the methodical conditions the quotient total cholesterol/HDL cholesterol showed the best separating power between normal and atherogenically endangered (increased risk greater than 6.0: specifity 92%, sensitivity 67% for patients with infarction, 57% for hypertensives, and 45% for obese persons). LDL-cholesterol, calculatorily established by means of Friedewald's formula, and the quotient LDL/HDL-cholesterol with circa the same specifity for the groups of patients had a clearly lower sensitivity (patients with infarction 38%, hypertensives 50%, obese 21%). The lower sensitivity of the quotient LDL-/HDL-cholesterol is traced back to methodical insufficiencies (calculation of the LDL-cholesterol from three lipid values). The determination of the quotient total cholesterol/HDL-cholesterol for the description of the atherogenic and coronary risk respectively, is recommended for practice.

Adult↗
PubMed1984

[Change in the concentration of lipoprotein parameters following swimming training in health resort patients].

On 197 patients who were admitted to a sanatorium for the purpose of a heart and circulation cure the influence of a daily swimming training, 20-30 minutes 6 times a week with intensities of about 50-60% VO2 max, on the lipid and lipoprotein spectre, respectively was investigated. In the whole group of patients HDL-cholesterol (HDL-C) did not change. In patients with increased risk n = 40 (initial HDL-C: lower than 0.91 mmol/l) HDL-C significantly increased in the course of the cure. In group I n = 157 (without increase of HDL-C) as well as in group II n = 40 (with increase of HDL-C) LDL-cholesterol significantly decreased. The lipid index after Klimov and the quotient LDL-C/HDL-C decreased at the end of the treatment and they showed the most distinct change in group II. The separation of the lipoproteins by disc electrophoresis and the establishment of their percental distribution resulted in a decrease of the beta-lipoproteins and an increase of the alpha-lipoproteins for the two groups (I and II). The quotient beta-lipoprotein/alpha-lipoprotein also significantly decreased in the two groups. For the apolipoproteins A and B in group II no statistically ascertained changes of concentration were established. At the end of the treatment in group I apolipoprotein B highly significantly decreased, while apolipoprotein A did not change. In accordance with the cholesterol index also the reduction of the apolipoprotein index apo B/A was significant.(ABSTRACT TRUNCATED AT 250 WORDS)

Apolipoproteins↗
PubMed1984

[Changes in heart and circulatory function following 4-weeks' endurance training].

On 144 patients with an average age of 47.1 years who were admitted to a four-week cure for heart and circulation the changed behaviour of heart and circulation at rest and under submaximal load by means of ergometry was assessed according to the variability of the pulse rate, the arterial blood pressure and the maximal volume of oxygen intake (VO2 max). A four-week training in perseverance run--performed according to several training impulses--effects a bradycardization, improvement in the patient's physical health (VO2 max) and a decrease of initially increased systolic and diastolic blood pressure values. A daily perseverance training of 60 min with intensities about 50% VO2 max is the most effective and also well applicable and dosable training impulse for older and less efficient persons during cure. The cardiac volume (size of the heart) does not show an ascertained change after cure.

Blood Pressure↗
PubMed1984

[A new peptide alkaloid from Discaria febrifuga Mart].

On the basis of spectroscopic investigations (1H-NMR, 13C-NMR, UV, IR and MS spectroscopy), elemental analysis and degradation reactions the structure of a new alkaloid discarine G from the bark extract of Discaria febrifuga Mart. is elucidated.

Acetylation↗