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Biomedical subjects

J Bernard

Publications and source records attributed to J Bernard.

At least 595 records · Page 33Linked to original sources

[Sylvain Buhot].

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History, 20th Century↗

AIDS agreement.

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France↗

Effect of 3M Coban Self-Adherent Wraps on edema and function of the burned hand: a case study.

Edema and limited function are common acute problems associated with hand burns. This case study examined the effects of 3M Coban Self-Adherent Wraps on edema and function in a 59-year-old male (46% TBSA flame injury) with newly skin grafted dorsally burned hands. At the time of each dressing change, circumferential measurements were taken of both hands and weekly active range of motion and grip strength measurements were recorded. The nine-hole peg test was used to appraise dexterity. During the 4-week study period, there was less edema, greater active range of motion and grip strength, and greater dexterity in the hand with 3M Coban Self-Adherent Wraps as compared with the control hand. This case study suggests that 3M Coban Self-Adherent Wraps were effective in reducing edema in the skin-grafted hand after skin grafting. It further appeared that the reduced edema may have contributed to improved hand function and that 3M Coban Self-Adherent Wraps as a compressive dressing do not impede hand function

Burns↗

Linguistic adaptations during spoken and multimodal error resolution.

Fragile error handling in recognition-based systems is a major problem that degrades their performance, frustrates users, and limits commercial potential. The aim of the present research was to analyze the types and magnitude of linguistic adaptation that occur during spoken and multimodal human-computer error resolution. A semiautomatic simulation method with a novel error-generation capability was used to collect samples of users' spoken and pen-based input immediately before and after recognition errors, and at different spiral depths in terms of the number of repetitions needed to resolve an error. When correcting persistent recognition errors, results revealed that users adapt their speech and language in three qualitatively different ways. First, they increase linguistic contrast through alternation of input modes and lexical content over repeated correction attempts. Second, when correcting with verbatim speech, they increase hyperarticulation by lengthening speech segments and pauses, and increasing the use of final falling contours. Third, when they hyperarticulate, users simultaneously suppress linguistic variability in their speech signal's amplitude and fundamental frequency. These findings are discussed from the perspective of enhancement of linguistic intelligibility. Implications are also discussed for corroboration and generalization of the Computer-elicited Hyperarticulate Adaptation Model (CHAM), and for improved error handling capabilities in next-generation spoken language and multimodal systems.

Computer Simulation↗

[Histomorphometric and biological data on osteoporosis due to immobilization].

The effect on the bones of immobilization was studied by means of quantitative histological methods on 34 biopsies of the iliac crest after different periods of immobilization in 28 patients, 22 of whom were immobilized by medullary lesions. At the same time a biochemical study was carried out on 68 immobilized patients over a 52-week period. This histomorphometric study included measurements of the absolute volume of trabecular bone, the volume of the osteoid matrix, the osteoclastic resorption surfaces, the size of the osteocyte lacunae, the thickness of the iliac cortical zones and the medullary adipose volume. 19 subjects received in addition double labeling with tetracycline with the object of carrying out a histodynamic study of the osteoblastic activity. The decrease in the absolute volume of the trabecular bone reached 33 percent of its original value and continued up to the 25th week, and was followed by stabilization at a value slightly higher than the vertebral fracture limit. Immobilization also led to an increase in the osteoclastic resorption surfaces and, secondarily, to an increase in the periosteocyte lacunae, a thinning of the iliac cortical zones, and a decrease in the volume of the osteoid matrix. Calciura increased as did total hydroxyprolinuria in parallel with an increase in the resorption surfaces. The histological and biochemical changes suggest a histodynamic hypothesis, according to which the longevity of the basic multicellular bone unit increases, leading to a new equilibrium characterized by very slow renewal of the bone.

Adult↗