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Biomedical subjects

J Battin

Publications and source records attributed to J Battin.

At least 73 records · Page 4Linked to original sources
PubMed1985

[Has prenatal ultrasonic diagnosis modified the prognosis of intestinal atresia? Results of a multicenter study].

A multicentric investigation concerning intestinal atresia diagnosed in french university hospitals from 1979 to 1983, has been done. Out of 96 exploitable cases coming from 8 centers, 28 correspond to intestinal atresias which had subject to prenatal echographic diagnosis: that is 29%. 15 of the 96 atresias were affected with trisomy. 21 which had not been recognised in utero. Concerning the isolated duodenal atresia, not accompanied by any other malformation, the post surgical evolution has been appreciated during the 12 months following the surgical operation. There was no statistically significant difference, in favour of the group of children whose malformation has been recognised in utero, concerning the number of post surgical complications. This result, apparently deceitful, can be explained by the early management of these malformations in specialised centers which have participated in this study.

Down Syndrome↗
PubMed1984

Betaxolol and propranolol in glucagon stimulation of growth hormone.

Both betaxolol and propranolol, beta blockers with different pharmacological properties, increase the reliability of somatotropic testing with glucagon. The combination of glucagon and betaxolol, however, is much better tolerated than that of glucagon and propranolol. The use of a beta 1 cardioselective adrenoceptor block for growth hormone testing is recommended.

Adolescent↗
PubMed1983

Pseudoscleroderma and phenylketonuria.

An infant girl with partial phenylketonuria developed pseudoscleroderma. After six years of follow up, both the neurologic and cutaneous conditions improved under a phenylalanine restricted diet. The probable roles of phenylalanine, tryptophan, tyrosine, and their metabolites may cause both conditions through possible transient hypersensitivity of cutaneous and muscular tissues.

Biopsy↗
PubMed1982

[Echography in gonadal dysgenesis and ovarian dystrophy (author's transl)].

Pelvic ultrasound examination was performed in 28 patients presenting with disorder in the onset of puberty (13 suggesting gonadal dysgenesis and 15, ovarian hyperandrogenism). Results of this investigation were compared with those of coelioscopy, in order to establish the respective value of each technique in the diagnosis of disorders of puberty in girls. In patients with gonadal dysgenesis, echography may show 'residual gonads but coelioscopy remains necessary when results of radiologic investigation are negative, when clinical or hormonal data suggest that ovarian function is present. Ultrasound examination showed one or two enlarged ovaries in all but one patients in whom coelioscopy had shown this abnormality. Pelvic echography is now the first test to be performed in girls with disorders of puberty as it often permits to avoid coelioscopy.

Adolescent↗
PubMed1980

Altered sensitivity to cholchicine and PHA in human cultured cells.

PHA-stimulated lymphocytes cultivated from a pair of human monozygotic twins yielded mostly tetraploid cells when colchicine was not used to arrest the metaphases. The rate of tetraploidy was also enhanced by colchicine in fibroblasts cultured without PHA. In in situ condition, larger than usual cells were observed. Other defects found in parental lymphocyte cultures included C-anaphase cells and increased cell aggregation. These results suggest a membrane mutation resulting in hypersensitivity to PHA and variant response to colchicine.

Cell Aggregation↗
PubMed1979

[Acanthosis nigricans, hirsutism and insulin-resistant diabetes].

Three girls, two of them being monozygotic twins, are affected with acanthosis nigricans and hirsutism, which worsened at the time of their puberty. The first one has primary amenorrhea and the twins complain of spaniomenorrhea. Furthermore, laboratory data concluded to diabetes, hyperinsulinism and resistance to insulin. This rare association of syndromes is not accidental but its significance remains unknown.

Acanthosis Nigricans↗
PubMed1977

[Monosomy 4 p-- (Wolf-Hirschorn's syndrome)].

The phenotype of the 4 p-- syndrome may be clinically distinguished from the one of the 5 p-- syndrome by the presence of fusion abnormalities of the median line. In the case reported, these abnormalities concerned a cleft palate, an iris coloboma and a fistula of the sacrum, in addition to an important hypotrophy and a severe mental retardation associated with epilepsy.

Abnormalities, Multiple↗